Patents Assigned to TONGJI UNIVERSITY SCHOOL OF MEDICINE
  • Lung-targeting nanobodies against pulmonary surfactant protein A and their preparation
    Patent number: 9908934
    Abstract: The present invention relates to pharmaceutical and medical technologies, and more particularly to novel nanobodies against pulmonary surfactant protein A (SP-A) and their preparation methods. The nanobodies of the present invention comprises an amino acid sequence having certain formula. The present invention also relates to nucleic acid sequences encoding the nanobodies, their preparation method and their applications. Immunohistochemistry and in vivo imaging show that the nanobodies of the present inventions have high lung-targeting specificity.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: March 6, 2018
    Assignees: Shanghai Pulmonary Hospital, TONGJI UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Huiping Li, Shanmei Wang
  • Lung-targeting nanobodies against pulmonary surfactant protein A and their preparation
    Patent number: 9228010
    Abstract: The present invention relates to pharmaceutical and medical technologies, and more particularly to novel nanobodies against pulmonary surfactant protein A (SP-A) and their preparation methods. The nanobodies of the present invention comprises an amino acid sequence having certain formula. The present invention also relates to nucleic acid sequences encoding the nanobodies, their preparation method and their applications. Immunohistochemistry and in vivo imaging show that the nanobodies of the present inventions have high lung-targeting specificity.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: January 5, 2016
    Assignee: Shanghai Pulmonary Hospital, Tongji University School of Medicine
    Inventors: Huiping Li, Shanmei Wang
  • LUNG-TARGETING NANOBODIES AGAINST PULMONARY SURFACTANT PROTEIN A AND THEIR PREPARATION
    Publication number: 20140314832
    Abstract: The present invention relates to pharmaceutical and medical technologies, and more particularly to novel nanobodies against pulmonary surfactant protein A (SP-A) and their preparation methods. The nanobodies of the present invention comprises an amino acid sequence having certain formula. The present invention also relates to nucleic acid sequences encoding the nanobodies, their preparation method and their applications. Immunohistochemistry and in vivo imaging show that the nanobodies of the present inventions have high lung-targeting specificity.
    Type: Application
    Filed: August 2, 2013
    Publication date: October 23, 2014
    Applicant: Shanghai Pulmonary Hospital, Tongji University School of Medicine
    Inventors: Huiping Li, Shanmei Wang