Abstract: In a particle counting system for sensing and counting particles, a sample fluid is drawn through an orifice from a sample chamber into a substantially enclosed fluid passage at a selected rate sufficient to maintain the pressure in the substantially closed fluid passage at a predetermined pressure level if the orifice and the substantially closed fluid passage are free from leaks and clogs. A sensor detects the actual pressure in the substantially closed fluid passage. The actual pressure is compared to the predetermined pressure level to identify clogs or leaks in the particle counting system. If a clog is identified, an automatic clog removal sequence is inititiated for dislodging or otherwise removing the clog from the particle counting system. The particle counting system is tested to determine if the clog has indeed been removed.