Patents Assigned to TORCH THERAPEUTICS
  • Method of using a bispecific antibody to conditionally inhibit a receptor signaling complex
    Patent number: 11111305
    Abstract: This invention describes the design of bispecific antibodies that function as conditionally effective therapeutics by binding to a functionally silent epitope on one component of a targeted signaling complex and simultaneously binding to a second protein, whose expression or accessibility is cell- or disease environment-specific, and whose antibody-driven proximity to the signaling complex leads to an alteration of signal transduction.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: September 7, 2021
    Assignee: TORCH THERAPEUTICS
    Inventors: Todd M. Kinsella, Donald G. Payan, Ramesh Bhatt, Kristen Baltgalvis