Patents Assigned to Torrent Pharmaceuticals Limited
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Patent number: 11560357Abstract: The present invention is directed to methods of producing substituted pyrazole based compounds through novel intermediates and unique processes for preparing such intermediates which enables synthesis of final product through commercially viable route of synthesis. The present invention is also directed to novel methods of producing substituted pyrazole based thyroid like compounds, and solid forms of 3-{4-[(7-hydroxy-6-methyl-indan-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-propanoic acid, its pharmaceutical compositions, and methods of preparation thereof.Type: GrantFiled: September 21, 2019Date of Patent: January 24, 2023Assignee: Torrent Pharmaceuticals LimitedInventors: Ramesh Chandra Gupta, Mohan Singaravel, Laxmikant Chhipa, Ashok Kasundra
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Publication number: 20220033358Abstract: The present invention is directed to methods of producing substituted pyrazole based compounds through novel intermediates and unique processes for preparing such intermediates which enables synthesis of final product through commercially viable route of synthesis. The present invention is also directed to novel methods of producing substituted pyrazole based thyroid like compounds, and solid forms of 3-{4-[(7-hydroxy-6-methyl-indan-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-propanoic acid, its pharmaceutical compositions, and methods of preparation thereof.Type: ApplicationFiled: September 21, 2019Publication date: February 3, 2022Applicant: TORRENT PHARMACEUTICALS LIMITEDInventors: Ramesh Chandra GUPTA, Mohan SINGARAVEL, Laxmikant CHHIPA, Ashok KASUNDRA
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Patent number: 10772879Abstract: This invention relates to pharmaceutical formulations comprising 1-(2-thien-2?-yl-2-oxo-ethyl)-3-(methanesulfonyl hydrazine carbonyl) pyridinium, its pharmaceutically acceptable salts, salt-cocrystals and co-crystals, particularly 1-(2-thien-2?-yl-2-oxo-ethyl)-3-5(methanesulfonyl hydrazine carbonyl) pyridinium chloride. The formulations are suitable for oral administration and also comprise a permeability enhancer or a suitable base or a mixture thereof. The formulations of this invention are for treating diseases associated with advanced glycation end products.Type: GrantFiled: April 5, 2016Date of Patent: September 15, 2020Assignee: Torrent Pharmaceuticals LimitedInventors: Chaitanya Dutt, Jaya Abraham, Vivek Mishra, Amit Kesarwani, Ramesh Chandra Gupta, Shailesh Deshpande, Shital Kumar Zambad, Anoop Mathur, Jignesh Kotecha, Sachin Latad, Manish Patel, Anita Chaudhari
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Patent number: 10717727Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.Type: GrantFiled: February 4, 2019Date of Patent: July 21, 2020Assignee: Torrent Pharmaceuticals LimitedInventors: Chaitanya Dutt, Rameshchandra Gupta, Manish Patel, Jaya Abraham, Vivek Mishra, Amit Kesarwani, Shailesh Deshpande, Shital Kumar Zambad, Anoop Mathur, Jignesh Kotecha, Sachin Latad, Anita Chaudhari
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Patent number: 10471005Abstract: Present invention relates to a low dose pharmaceutical composition, preferably oral composition comprising therapeutically effective amount of [(2-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H,5H-10-thia-1,4a-diaza-benzo[a]azulene-3-carbonyl)-amino]-acetic acid (compound A) in the range of 2.5 mg to 60 mg. Present invention also relates to a method of treating inflammatory bowel disease in a mammal by administrating said low dose pharmaceutical composition. Further, present invention relates to a use of the compound A for the preparation of low dose pharmaceutical composition for the treatment of inflammatory bowel disease in a mammal.Type: GrantFiled: February 22, 2017Date of Patent: November 12, 2019Assignee: Torrent Pharmaceuticals LimitedInventors: Chaitanya Dutt, Vijay Chauthaiwale, Ram Gupta, Shitalkumar Zambad, Shailesh Deshpande, Jignesh Kotecha, Ramesh Gupta, Sanjay Srivastava, Laxmikant Chhipa, Jaya Abraham
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Publication number: 20190169175Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.Type: ApplicationFiled: February 4, 2019Publication date: June 6, 2019Applicant: TORRENT PHARMACEUTICALS LIMITEDInventors: Chaitanya DUTT, Rameshchandra GUPTA, Manish PATEL, Jaya ABRAHAM, Vivek MISHRA, Amit KESARWANI, Shailesh DESHPANDE, Shital Kumar ZAMBAD, Anoop MATHUR, Jignesh KOTECHA, Sachin LATAD, Anita CHAUDHARI
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Patent number: 10292948Abstract: Disclosed herein are pharmaceutical compositions for nasal administration comprising tapentadol, their preparation and their use in the treatment of pain.Type: GrantFiled: January 10, 2018Date of Patent: May 21, 2019Assignee: Torrent Pharmaceuticals LimitedInventors: Jaya Abraham, Vivek Mishra, Vipul Mittal, Kiran Chaudhari
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Publication number: 20190127381Abstract: Provided herein are novel fused pyrimidinone derivatives of Formula I and synthetic intermediates that are useful in preparing the compounds of formula (I). Further provided herein is a method for preparation of a compound of formula (I) or intermediates, a pharmaceutical composition comprising a compound of formula (I), and use of a compound of formula (I).Type: ApplicationFiled: April 25, 2017Publication date: May 2, 2019Applicant: TORRENT PHARMACEUTICALS LIMITEDInventors: Chaitanya DUTT, Deepa JOSHI, Milind RODE, Sanjay SRIVASTAVA, Davinder TULI, Ramesh Chandra GUPTA, Deepak RAI, Prashant JAMADARKHANA, Shailesh DESHPANDE, Vivek MISHRA, Jaya ABRAHAM
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Patent number: 10233175Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.Type: GrantFiled: April 5, 2016Date of Patent: March 19, 2019Assignee: Torrent Pharmaceuticals LimitedInventors: Chaitanya Dutt, Rameshchandra Gupta, Manish Patel, Jaya Abraham, Vivek Mishra, Amit Kesarwani, Shailesh Deshpande, Shital Kumar Zambad, Anoop Mathur, Jignesh Kotecha, Sachin Latad, Anita Chaudhari
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Patent number: 10227361Abstract: The present invention relates to novel fused Imidazobenzothiazole derivatives, their pharmaceutically acceptable salts, and their isomers, stereoisomers, atropisomers, conformers, tautomers, polymorphs, hydrates, solvates and N-oxide. The present invention also encompasses pharmaceutically acceptable compositions of said compounds and process for preparing novel compounds. The invention further relates to the use of the above-mentioned compounds for the preparation of medicament for use as pharmaceuticals.Type: GrantFiled: January 3, 2018Date of Patent: March 12, 2019Assignee: Torrent Pharmaceuticals LimitedInventors: Pundlik Shinde, Sanjay Srivastava, Davindar Tuli, Deepak Rai, Prashant Gj, Shailesh Deshpande, Rameshchandra Gupta, Vijay Chauthaiwale, Chaitanya Dutt
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Patent number: 10206923Abstract: Present invention relates to a stable pharmaceutical composition comprising intimate mixture of alogliptin and metformin, and suitable pharmaceutically acceptable excipient/s; wherein metformin is present in about 3.3 parts or more parts by weight relative to 100 parts by weight of the total weight of part comprising alogliptin. Invention also encompasses various processes of preparing said pharmaceutical composition and its use in improving glycemic control in adults with type 2 diabetes mellitus.Type: GrantFiled: August 17, 2016Date of Patent: February 19, 2019Assignee: Torrent Pharmaceuticals LimitedInventors: Jaya Abraham, Suryakant Navale, Pradip Mukhopadhyay, Muzaffar Madny
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Publication number: 20180235966Abstract: Present invention relates to a stable pharmaceutical composition comprising intimate mixture of alogliptin and metformin, and suitable pharmaceutically acceptable excipient/s; wherein metformin is present in about 3.3 parts or more parts by weight relative to 100 parts by weight of the total weight of part comprising alogliptin. Invention also encompasses various processes of preparing said pharmaceutical composition and its use in improving glycemic control in adults with type 2 diabetes mellitus.Type: ApplicationFiled: August 17, 2016Publication date: August 23, 2018Applicant: TORRENT PHARMACEUTICALS LIMITEDInventors: Jaya ABRAHAM, Suryakant NAVALE, Pradip MUKHOPADHYAY, Muzaffar MADNY
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Publication number: 20180193290Abstract: Disclosed herein are pharmaceutical compositions for nasal administration comprising tapentadol, their preparation and their use in the treatment of pain.Type: ApplicationFiled: January 10, 2018Publication date: July 12, 2018Applicant: Torrent Pharmaceuticals LimitedInventors: Jaya ABRAHAM, Vivek MISHRA, Vipul MITTAL, Kiran CHAUDHARI
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Publication number: 20180127437Abstract: The present invention relates to novel fused Imidazobenzothiazole derivatives, their pharmaceutically acceptable salts, and their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates, solvates and N-oxide. The present invention also encompasses pharmaceutically acceptable compositions of said compounds and process for preparing novel compounds. The invention further relates to the use of the above-mentioned compounds for the preparation of medicament for use as pharmaceuticals.Type: ApplicationFiled: January 3, 2018Publication date: May 10, 2018Applicant: TORRENT PHARMACEUTICALS LIMITEDInventors: Pundlik SHINDE, Sanjay SRIVASTAVA, Davindar TULI, Deepak RAI, Prashant GJ, Shailesh DESHPANDE, Rameshchandra GUPTA, Vijay CHAUTHAIWALE, Chaitanya DUTT
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Patent number: 9963463Abstract: The present invention relates to novel indanyl urea derivatives of formula (I): their pharmaceutically acceptable salts, and their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the compounds for the preparation of medicament for use as pharmaceuticals.Type: GrantFiled: August 27, 2015Date of Patent: May 8, 2018Assignee: Torrent Pharmaceuticals LimitedInventors: Milind Rode, Sanjay Srivastava, Davindar Tuli, Deepak Rai, Prashant Gj, Shailesh Deshpande, Rameshchandra Gupta, Vijay Chauthaiwale, Chaitanya Dutt
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Publication number: 20180118728Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.Type: ApplicationFiled: April 5, 2016Publication date: May 3, 2018Applicant: TORRENT PHARMACEUTICALS LIMITEDInventors: Chaitanya DUTT, Rameshchandra GUPTA, Manish PATEL, Jaya ABRAHAM, Vivek MISHRA, Amit KESARWANI, Shailesh DESHPANDE, Shital Kumar ZAMBAD, Anoop MATHUR, Jignesh KOTECHA, Sachin LATAD, Anita CHAUDHARI
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Publication number: 20180110763Abstract: This invention relates to pharmaceutical formulations comprising 1-(2-thien-2?-yl-2-oxo-ethyl)-3-(methanesulfonyl hydrazine carbonyl) pyridinium, its pharmaceutically acceptable salts, salt-cocrystals and co-crystals, particularly 1-(2-thien-2?-yl-2-oxo-ethyl)-3-5(methanesulfonyl hydrazine carbonyl) pyridinium chloride. The formulations are suitable for oral administration and also comprise a permeability enhancer or a suitable base or a mixture thereof.Type: ApplicationFiled: April 5, 2016Publication date: April 26, 2018Applicant: TORRENT PHARMACEUTICALS LIMITEDInventors: Chaitanya DUTT, Jaya ABRAHAM, Vivek MISHRA, Amit KESARWANI, Ramesh Chandra GUPTA, Shailesh DESHPANDE, Shital Kumar ZAMBAD, Anoop MATHUR, Jignesh KOTECHA, Sachin LATAD, Manish PATEL, Anita CHAUDHARI
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Patent number: 9908898Abstract: The present invention relates to novel fused Imidazobenzothiazole derivatives, their pharmaceutically acceptable salts, and their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates, solvates and N-oxide. The present invention also encompasses pharmaceutically acceptable compositions of said compounds and process for preparing novel compounds. The invention further relates to the use of the above-mentioned compounds for the preparation of medicament for use as pharmaceuticals.Type: GrantFiled: March 24, 2015Date of Patent: March 6, 2018Assignee: Torrent Pharmaceuticals LimitedInventors: Pundlik Shinde, Sanjay Srivastava, Davindar Tuli, Deepak Rai, Prashant Gj, Shailesh Deshpande, Rameshchandra Gupta, Vijay Chauthaiwale, Chaitanya Dutt
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Publication number: 20170247390Abstract: The present invention relates to novel indanyl urea derivatives, their pharmaceutically acceptable salts, and their isomers, stereoisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the compounds for the preparation of medicament for use as pharmaceuticals.Type: ApplicationFiled: August 27, 2015Publication date: August 31, 2017Applicant: TORRENT PHARMACEUTICALS LIMITEDInventors: Milind RODE, Sanjay SRIVASTAVA, Davindar TULI, Deepak RAI, Prashant GJ, Shailesh DESHPANDE, Rameshchandra GUPTA, Vijay CHAUTHAIWALE, Chaitanya DUTT
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Publication number: 20170157129Abstract: Present invention relates to a low dose pharmaceutical composition, preferably oral composition comprising therapeutically effective amount of [(2-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H,5H-10-thia-1,4a-diaza-benzo[a]azulene-3-carbonyl)-amino]-acetic acid (compound A) in the range of 2.5 mg to 60 mg. Present invention also relates to a method of treating inflammatory bowel disease in a mammal by administrating said low dose pharmaceutical composition. Further, present invention relates to a use of the compound A for the preparation of low dose pharmaceutical composition for the treatment of inflammatory bowel disease in a mammal.Type: ApplicationFiled: February 22, 2017Publication date: June 8, 2017Applicant: TORRENT PHARMACEUTICALS LIMITEDInventors: Chaitanya DUTT, Vijay CHAUTHAIWALE, Ram GUPTA, Shitalkumar ZAMBAD, Shailesh DESHPANDE, Jignesh KOTECHA, Ramesh GUPTA, Sanjay SRIVASTAVA, Laxmikant CHHIPA, Jaya ABRAHAM