Abstract: A blood clarification device wherein a means for measuring blood pressure comprises (a) a needle-detector which is much thinner than the puncture needle and capable of being smoothly inserted into a blood vessel from outside through an inner aperture of the puncture needle, (b) an insertion aperture, for allowing fluid-tight insertion of the needle-detector, positioned on a wall of the blood supply passage in the vicinity of the puncture needle, and (c) a pressure transducer for detecting the blood pressure inside the blood vessel transmitted thereto via the needle-detector. In a blood clarification apparatus of the present invention, blood pressure inside a blood vessel is transmitted to a pressure transducer via a needle-detector during dialysis/filtration operation and blood pressure of a patient is detected continuously and automatically by the pressure transducer.

Abstract: A hemodiafiltration system which enables concurrent performance, in a single system, of hemodialysis and hemofiltration includes a dialyzer, consisting of a casing and at least one semipermeable membrane accommodated therein for dialyzing and purifying body fluid such as blood, plasma, etc., through contacting of the body fluid and dialyzate via the semipermeable membrane, and pumps for causing the dialyzate to flow through the dialyzer. A controller repeatedly changes the difference between the inflow amount of the dialyzate into the dialyzer per unit time and the outflow amount of the same from the dialyzer per unit time from a positive value to a negative value and then from negative to positive, whereby the repeated operation of taking or sucking out aqueous component or constituent and accompanying waste molecules from the body fluid followed by infusing or forcing a compensatory amount of dialyzate into the body fluid is made possible.