Patents Assigned to Tosoh Corporation
  • Publication number: 20250026784
    Abstract: An antibody separation method including a step of applying a solution containing an antibody to a column filled with an antibody adsorption material containing an insoluble porous carrier and an Fc-binding protein immobilized on the carrier and adsorbing the antibody onto the antibody adsorption material; and a step of applying a buffer solution to the column and eluting the antibody adsorbed onto the antibody adsorption material with a pH gradient, wherein the pH gradient is a step gradient in which a pH of the buffer solution is lowered in steps, and wherein the magnitude of pH decrease is 0.1 or more and less than 1.
    Type: Application
    Filed: November 14, 2022
    Publication date: January 23, 2025
    Applicant: TOSOH CORPORATION
    Inventors: Yuta HAYAKAWA, Naomasa TANIGUCHI, Yosuke TERAO
  • Publication number: 20250011590
    Abstract: There has been a demand for an optical film having excellent glass-range photoelastic coefficient and a polarizing plate which uses this optical film. The present invention provides an optical film which is characterized by containing an ester-based resin that contains 50% by mole or more of a fumaric acid ester residue unit represented by formula (1) and having a negative birefringence, and a photoelasticity regulator having a positive birefringence, and which is also characterized in that the absolute value of the glass-range photoelastic coefficient thereof is 5×10?12 Pa?1 or less. (In the formula, each of R1 and R2 independently represents a linear alkyl group having 1 to 12 carbon atoms, a branched alkyl group having 3 to 12 carbon atoms, or a cyclic alkyl group having 3 to 6 carbon atoms.
    Type: Application
    Filed: November 16, 2022
    Publication date: January 9, 2025
    Applicant: TOSOH CORPORATION
    Inventors: Takuya KOMINE, Asuka YOSHIMURA, Takahiro KITAGAWA
  • Publication number: 20250002543
    Abstract: An immunoglobulin-binding protein has an improved chemical stability, especially having an improved alkaline stability, or an immunoglobulin-binding protein capable of allowing antibody elution under mild pH conditions, and an adsorbent on which the protein is immobilized. The alkaline stability or the antibody elution property is improved by including an amino acid sequence which is the same as an amino acid sequence of an immunoglobulin-binding domain of protein L derived from a bacterium belonging to the genus Finegoldia except that the amino acid residue(s) at a particular position(s) of the domain in the amino acid sequence is/are substituted with another particular amino acid residues(s).
    Type: Application
    Filed: October 24, 2022
    Publication date: January 2, 2025
    Applicant: TOSOH CORPORATION
    Inventors: Takatoshi HASEMI, Akihiro IWASE, Satoshi ENDO, Toru TANAKA
  • Publication number: 20240425620
    Abstract: The present invention provides a resin which enables the production of an organic field effect transistor element which has excellent resistance to bias stress by being used as a gate insulating film layer for an organic field effect transistor. The present invention provides a resin which comprises a repeating unit represented by Formula (1) and a repeating unit represented by Formula (2), wherein: the repeating unit represented by Formula (2) has a HOMO level of ?6.4 eV or less; and 20% by mole or more of the repeating unit represented by Formula (2) is contained relative to the total amount of the repeating unit represented by Formula (1) and the repeating unit represented by Formula (2).
    Type: Application
    Filed: October 24, 2022
    Publication date: December 26, 2024
    Applicant: TOSOH CORPORATION
    Inventors: Yuta IIJIMA, Shohei YUMINO, Takashi FUKUDA, Rei SHIWAKU, Shinya OKU
  • Patent number: 12174194
    Abstract: A method of collecting and detecting a tumor cell contained in a sample in distinction from a contaminant cell is provided. The tumor cell contained in the sample are collected and detected in distinction from the contaminant cell by detecting any of the following polypeptides or a gene encoding the polypeptide present in the sample: (i) a polypeptide containing at least the amino acid sequence of any of six sequences such as TM4SF1 (GenBank No. NP_055035.1) and TNFRSF12A (GenBank No. NP_057723.1); (ii) a polypeptide containing at least an amino acid sequence having a homology of not less than 70% to the amino acid sequence described above; and (iii) a polypeptide containing at least a splicing variant of the amino acid sequence (the amino acid sequence of (i) or (ii) described above).
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: December 24, 2024
    Assignee: TOSOH CORPORATION
    Inventors: Yuichi Kumaki, Sayaka Hirai, Makoto Otsuki, Daisuke Miki, Toru Futami
  • Patent number: 12173398
    Abstract: A Cr—Si sintered body contains Cr and Si. The Cr—Si sintered body contains a crystalline CrSi2 phase and a crystalline Si phase. A content of the Si phase in the Cr—Si sintered body is 40% by mass or more. A relative density of the Cr—Si sintered body relative to a true density of the Cr—Si sintered body is 95% or more. The CrSi2 phase has an average crystal grain size of 40 ?m or less, and the Si phase has an average crystal grain size of 30 ?m or less. A total content of impurities in the Cr—Si sintered body is 200 ppm by mass or less, and the impurities are composed of at least one element selected from the group consisting of Mn, Fe, Mg, Ca, Sr, and Ba.
    Type: Grant
    Filed: March 24, 2021
    Date of Patent: December 24, 2024
    Assignee: TOSOH CORPORATION
    Inventors: Hiroyuki Hara, Masami Mesuda, Ayaka Masuda
  • Publication number: 20240409471
    Abstract: A zirconia powder including 2% by mole or more and 8% by mole or less of a stabilizing element and 50 ppm or less of titanium (Ti) and having an activation energy of 225 kJ/mol or more and 300 kJ/mol or less, which provides a zirconia powder capable of producing a sintered body with high translucency even by pressureless sintering and suitable for industrial production, a method for producing the zirconia powder, a method for producing a calcined body using the zirconia powder, and a method for producing a sintered body using the zirconia powder. Such a powder is produced by a method including adjusting a pH of a raw material solution containing a zirconium source and a stabilizing element source to 3.5 or more and 5.5 or less; heating the raw material solution to produce a zirconia sol solution; mixing the zirconia solution and an alkaline solution; and heat-treating.
    Type: Application
    Filed: November 24, 2022
    Publication date: December 12, 2024
    Applicant: TOSOH CORPORATION
    Inventors: Koji MATSUI, Kenji IMAI, Kohei HOSOI
  • Publication number: 20240400826
    Abstract: There are provided a polyarylene sulfide composition that contains a post-consumer recycled polyamide and a fibrous filler without compromising the intrinsic heat resistance, chemical resistance, flowability and other characteristics of a polyarylene sulfide and a method for producing it. The polyarylene sulfide composition comprises a polyarylene sulfide (A) having a melt viscosity of 100 to 3000 poises as measured under the conditions of a measuring temperature of 315° C. and a load of 10 kg using a capillary rheometer flow tester fitted with a 1-mm diameter and 2-mm long die, 10 to 90 parts by weight of a post-consumer recycled polyamide (B) per 100 parts by weight of the polyarylene sulfide (A) and 20 to 110 parts by weight of a fibrous filler (C) per a total of 100 parts by weight of the polyarylene sulfide (A) and the post-consumer recycled polyamide (B).
    Type: Application
    Filed: October 14, 2022
    Publication date: December 5, 2024
    Applicant: TOSOH CORPORATION
    Inventors: Takeshi HARUNARI, Hiroki INOUE
  • Publication number: 20240407260
    Abstract: Provided are a material for a light receiving element having excellent hole transport characteristics, and an organic light receiving element using the same. A material for a light receiving element is used that includes a compound represented by general formula (1) or general formula (2). Ar2 and Ar3 are preferably cyano groups. Ar and Ar5 are preferably cyano groups.
    Type: Application
    Filed: June 28, 2022
    Publication date: December 5, 2024
    Applicant: TOSOH CORPORATION
    Inventors: Nobumichi ARAI, Takeshi OKADA, Yasuhiro TAKAHASHI, Keisuke NOMURA
  • Publication number: 20240393349
    Abstract: Provided are a method of simply detecting Alzheimer's disease (AD) and a method of simply stratifying AD pathological phases, and a reagent that can be used for the methods, based on the fact that measurement of a protein contained in extracellular vesicles enables detection of Alzheimer's disease and stratification of AD pathological phases.
    Type: Application
    Filed: September 8, 2022
    Publication date: November 28, 2024
    Applicants: TOSOH CORPORATION, JAPANESE FOUNDATION FOR CANCER RESEARCH
    Inventors: Kohei YUYAMA, Yukifusa IGETA, Koji UEDA
  • Publication number: 20240382928
    Abstract: It is an object of the present disclosure to provide a YFl-type zeolite with a small difference in desorption starting temperature due to hydrothermal durability treatment, a method for producing the YFl-type zeolite, a hydrocarbon adsorbent containing the YFl-type zeolite and a hydrocarbon adsorption method using the YFl-type zeolite The YFl-type zeolite is characterized in that the ratio of the mass of extra-framework aluminum to the mass of contained aluminum is 0% by mass or more and 28% by mass or less.
    Type: Application
    Filed: May 31, 2022
    Publication date: November 21, 2024
    Applicant: TOSOH CORPORATION
    Inventors: Ryo MITSUHASHI, Naoto NAKAZAWA, Toyohiro USUI
  • Publication number: 20240376012
    Abstract: Provided is a powder composition that includes, as a matrix, a zirconia having a high content of a stabilizing element and that can provide, through short-time sintering, a sintered body satisfying translucency and mechanical strength required for dental prosthetic materials, in particular, prosthetic anterior teeth. Provided is a powder composition including two or more stabilized zirconias having different contents of a stabilizing element, in which the powder composition has a content of the stabilizing element of more than 4.0 mol % and 5.8 mol % or less, a rate of change in thermal shrinkage rate per unit temperature at 1,300° C. is 0.07% C?1 or less, and the contents of the stabilizing element of the stabilized zirconias are each 8.0 mol % or less.
    Type: Application
    Filed: September 15, 2022
    Publication date: November 14, 2024
    Applicant: TOSOH CORPORATION
    Inventors: Sho AZECHI, Yuya HIGUCHI, Hiroyuki FUJISAKI, Hitoshi NAGAYAMA, Kiyotaka KAWAMURA
  • Patent number: 12134677
    Abstract: The present invention relates to a hydrophilizing agent for producing a self-emulsifying polyisocyanate composition, the hydrophilizing agent comprising an anionic compound represented by the following formula (1): wherein X represents a sulfo group or a hydroxysulfonyloxy group, R1 represents a straight-chain or branched alkylene group, and R2 represents a straight-chain or branched alkyl group; the total number of carbon atoms included in R1 and R2 is 6 or more and less than 14, and one or two or more carbon atoms in the groups R1 and R2 are optionally replaced with an oxygen atom(s).
    Type: Grant
    Filed: February 26, 2019
    Date of Patent: November 5, 2024
    Assignees: TOSOH CORPORATION, SAGAMI CHEMICAL RESEARCH INSTITUTE
    Inventors: Motomu Kita, Shimou Chinson, Munenori Inoue, Masahiro Nagaoka, Hiroaki Adachi, Aki Maeda
  • Patent number: 12134584
    Abstract: Disclosed is a coating layer-bonded continuous ceramic fiber formed from a continuous ceramic fiber having a coating layer of a metal compound with a thickness of 50 nm or less on the surface. Also disclosed is a ceramic matrix composite material having the above-described coating layer-bonded continuous ceramic fiber.
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: November 5, 2024
    Assignee: TOSOH CORPORATION
    Inventors: Isao Yamashita, Yushi Nawata
  • Publication number: 20240359375
    Abstract: A metal member-polyarylene sulfide resin member composite having an air-tight joint between the metal member and the polyarylene sulfide resin member and a method for its production are provided. A metal member-polyarylene sulfide resin member composite comprising a metal member and a polyarylene sulfide member which is obtained by injection molded direct joining, wherein the polyarylene sulfide member is made of a polyarylene sulfide resin composition which satisfies all of the following (1) to (3): (1) it has a melt crystallization peak temperature of at least 200° C. and at most 230° C., (2) it has an MFR of at least 20 g/10 minutes and at most 150 g/10 minutes, and (3) it comprises 100 parts by weight of a polyarylene sulfide resin (A), from 5 to 25 parts by weight of a modified ethylene copolymer (B) and from 10 to 120 parts by weight of glass fiber (C).
    Type: Application
    Filed: August 3, 2022
    Publication date: October 31, 2024
    Applicant: TOSOH CORPORATION
    Inventor: Takeshi HARUNARI
  • Patent number: 12110304
    Abstract: Provided are a divalent phosphazenium salt which is neutral and is excellent in thermal stability and aldehyde scavenging ability, and a method for producing the same. Also provided are a polyalkylene oxide composition having a volatile aldehyde amount reduced, having generation of odor and turbidity suppressed and being excellent in urethanization reactivity, and a method for producing such a polyalkylene oxide composition, as well as a polyurethane-forming composition containing the polyalkylene oxide composition. A divalent phosphazenium salt having a specific structure. Also, a polyalkylene oxide composition comprising a divalent phosphazenium salt having a specific structure and a polyalkylene oxide, a method for producing the same, and a polyurethane-forming composition containing the same.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: October 8, 2024
    Assignee: TOSOH CORPORATION
    Inventors: Yoshiaki Inoue, Toshihide Yamamoto, Katsuaki Mori
  • Patent number: 12104007
    Abstract: An allophanate group-containing polyisocyanate composition that contributes to the formation of a polyurethane resin with fewer bubbles is provided. Disclosed is an allophanate group-containing polyisocyanate composition (C) including a reaction product of diphenylmethane diisocyanate (A) and a hydroxyl group-containing compound (B), wherein the hydroxyl group-containing compound (B) includes a hydroxyl group-containing polymethylsiloxane compound (B-1) in an amount of 1 ppm or more and 300 ppm or less.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: October 1, 2024
    Assignee: TOSOH CORPORATION
    Inventors: Mitsushige Ikemoto, Futoshi Oota
  • Patent number: 12101991
    Abstract: Provided are (i) a solution for forming an organic semiconductor layer which solution has excellent coating property, (ii) an organic semiconductor which is produced with use of the solution and which has high heat resistance, (iii) a layer which contains the organic semiconductor, and (iv) an organic thin film transistor which exhibits high electrical properties. A composition containing: an organic semiconductor; and a polymer (1) having at least one unit selected from the group consisting of units represented by formulae (1-a), (1-b) and (1-c) given below. A composition containing the organic semiconductor, the polymer (1) and an organic solvent can be suitably used as a solution for forming an organic semiconductor layer.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: September 24, 2024
    Assignee: TOSOH CORPORATION
    Inventors: Takahiro Mori, Takashi Fukuda
  • Publication number: 20240308195
    Abstract: A stretched polyethylene film for lamination, which comprises a polyethylene (A) having a weight average molecular weight (Mw) as measured by gel permeation chromatography of from 70,000 to 250,000, a proportion of fractions with a molecular weight of 10,000 or less of 8 wt % or less, and a density as measured in accordance with JIS K6922-1 (1997) of from 945 to 980 kg/m3, and has at least one peak in a range of 135° C. or higher in an endothermic curve as measured by differential scanning calorimetry, the film having high recyclability and excellent in heat resistance.
    Type: Application
    Filed: February 18, 2022
    Publication date: September 19, 2024
    Applicant: TOSOH CORPORATION
    Inventors: Shingo KOUDA, Shoji NISHIO, Kenichi SUZUKI
  • Publication number: 20240301197
    Abstract: In regard to a conventionally known resin composition for an antistatic hard coating to which an ionic liquid is added and an antistatic hard coating using it, there is a problem that it is difficult to achieve both an antistatic ability and high hardness. In order to solve the problem, used is a resin composition for an ultraviolet curing hard coating, the resin composition containing: an electrically conductive polymer that contains polythiophene (A) including at least two structural units represented by a specific general formula; an ultraviolet curable resin (B); and a solvent (C).
    Type: Application
    Filed: March 4, 2024
    Publication date: September 12, 2024
    Applicant: TOSOH CORPORATION
    Inventors: Haruka AOKI, Sadayoshi HAYASHI, Hirokazu YANO, Hirofumi MIYAKE