Patents Assigned to Tosoh Corporation
  • Patent number: 11439721
    Abstract: To provide an aldehyde scavenger and a method for removing aldehydes by using the same, for quickly and continuously capturing aldehydes. An aldehyde scavenger comprising at least one O-substituted hydroxylamine or at least one chemically acceptable salt thereof, is used against an aldehyde generation source.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: September 13, 2022
    Assignees: TOSOH CORPORATION, Sagami Chemical Research Institute
    Inventors: Yukinori Sudo, Takahiro Masuda, Osamu Kobayashi, Takuri Ozaki, Kenji Hirai
  • Publication number: 20220274952
    Abstract: An object of the present invention is to provide a cyclic azine compound exhibiting both excellent driving voltage characteristics and excellent current efficiency characteristics. The desired cyclic azine compound has a specific structure represented by formula (1).
    Type: Application
    Filed: July 22, 2020
    Publication date: September 1, 2022
    Applicants: TOSOH CORPORATION, SAGAMI CHEMICAL RESEARCH INSTITUTE
    Inventors: Naoki UCHIDA, Hidenori AIHARA, Takuya YAMAGATA, Naoki HAYAKAWA, Natsumi NAKAJIMA, Kazuki HATTORI, Fuminari UEHARA, Yohei ONO, Masaya HIRANO, Yuta MORINAKA, Keisuke NOMURA, Eriko OHTA, Tomohiro SHONO, Kana OIKE, Kazushi HAYASHI, Keiya AOYAGI, Kosuke SATO, Toshiki NISHIURA
  • Patent number: 11427828
    Abstract: The present invention addresses the problem of providing FcRn having improved stability with respect to heat and acids, a method for producing said FcRn, an antibody adsorbent in which said FcRn is used, and an antibody isolation method in which said adsorbent is used. The above problem is solved by substituting an amino acid residue at a specific position in an extracellular region of a human FcRn ? chain and/or a ?2 microglobulin region of a human FcRn ? chain by another specific amino acid.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: August 30, 2022
    Assignee: TOSOH CORPORATION
    Inventors: Yosuke Terao, Naoki Yamanaka, Natsuko Kizu, Satoshi Endo, Seigo Oe
  • Patent number: 11414475
    Abstract: The problem to be addressed by the present invention is to provide improved recombinant Fc?RIIb and Fc?RIIa that do not require refolding and exhibit high productivity and thermal stability, and to provide a method for producing the same. Said problem is solved by improved recombinant Fc?RIIb comprising at least the amino acid residues of the extracellular domain of human Fc?RIIb (No. 43 to No. 215 in UniProt No. P31994), wherein, in said amino acid residues, at least one amino acid substitution has occurred at a position corresponding to No. 82, 94, 98, 104, 105, or 139 in UniProt No. P31994. Said problem is also solved by improved recombinant Fc?RIIa comprising at least the amino acid residues of the extracellular domain of human Fc?RIIa (No. 34 to No. 206 in UniProt No. P12318-1), wherein, in said amino acid residues, at least one amino acid substitution has occurred at a position corresponding to No. 73, 85, 89, 95, 96, or 130 in UniProt No. P12318-1.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: August 16, 2022
    Assignees: TOSOH CORPORATION, SAGAMI CHEMICAL RESEARCH INSTITUTE
    Inventors: Kouta Hatayama, Teruhiko Ide, Hiroyuki Ito, Yosuke Terao, Naoki Yamanaka, Satoshi Endo
  • Patent number: 11407884
    Abstract: To provide a resin composition comprising a cyclic polyolefin and an ethylene polymer, having excellent impact resistance and having high transparency maintained. A resin composition comprising from 5 to 95 parts by weight of a cyclic polyolefin (A) and from 5 to 95 parts by weight of an ethylene polymer (B) which satisfies the following requirements (a) to (d) (the total amount of (A) and (B) is 100 parts by weight): (a) the density is from 930 to 960 kg/m3; (b) MFR is from 0.1 to 15.0 g/10 min; (c) in molecular weight measurement by gel permeation chromatography, two peaks are observed, and the ratio (Mw/Mn) of the weight average molecular weight (Mw) to the number average molecular weight (Mn) is within a range of from 3.0 to 7.0; and (d) a fraction having Mn of at least 100,000 as obtained by molecular weight fractionation, has at least 0.15 long-chain branches per 1,000 carbon atoms of the main chain.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: August 9, 2022
    Assignee: TOSOH CORPORATION
    Inventor: Shimpei Hama
  • Publication number: 20220227636
    Abstract: Provided is at least one of a production method that can obtain AEI zeolite that has a silica-to-alumina molar ratio suitable as a nitrogen oxide-reducing catalyst or a support thereof and that involves a shorter crystallization time and higher yield compared to a typical AEI zeolite production method that does not use crystalline aluminosilicate as a starting material, or an AEI zeolite production method that is expected to be industrially applicable. An AEI zeolite production method includes hydrothermally processing an amorphous composition containing an amorphous silica source, an amorphous alumina source, an alkali source and water, and then crystallizing a raw material composition obtained by mixing an organic structure-directing agent and the amorphous composition.
    Type: Application
    Filed: May 27, 2020
    Publication date: July 21, 2022
    Applicant: TOSOH CORPORATION
    Inventors: Tomoya ISHIKAWA, Yoshitaka YAMASAKI
  • Publication number: 20220213356
    Abstract: The purpose is to provide a resin composition and a film for lid material which excel in sealability and adhesiveness to plastic containers, especially containers made of polyethylene terephthalate, polylactic acid, polystyrene, or polypropylene, and are suitably usable as sealant layers of lid materials for containers. Provided is a resin composition including: an ethylene-vinyl acetate copolymer (A) by 60-95 parts by weight, the ethylene-vinyl acetate copolymer (A) having a vinyl acetate content (VA) of 3-13% by weight, and having a ratio Qw between a weight-average molecular weight (Mw) and a number-average molecular weight (Mn) of 1.5-4.5; and a tackifier resin (B) by 5-40 parts by weight, where a total amount of (A) and (B) is 100 parts by weight.
    Type: Application
    Filed: March 18, 2020
    Publication date: July 7, 2022
    Applicant: TOSOH CORPORATION
    Inventors: Takashi HEMMI, Isao MORISHITA, Shingo KOUDA
  • Publication number: 20220212999
    Abstract: There is provided a raw material for a zirconia sintered body formed by pressureless sintering and having a high fracture toughness value measured by an SEPB method, a sintered body formed from the raw material, and a method for producing at least one of the raw material and the sintered body. Also provided is a sintered body that includes zirconia that contains a stabilizer and having a monoclinic fraction of 0.5% or more. Such a sintered body is produced by a method including using a powder that contains a stabilizer and zirconia with a monoclinic fraction of more than 70%, wherein monoclinic zirconia has a crystallite size of more than 23 nm and 80 nm or less.
    Type: Application
    Filed: April 6, 2020
    Publication date: July 7, 2022
    Applicant: TOSOH CORPORATION
    Inventors: Koji MATSUI, Kohei HOSOI
  • Publication number: 20220212933
    Abstract: To provide a sodium transition metal polyanion suitable as a cathode active material of a sodium secondary battery, and a simple method for producing it. A sodium transition metal polyanion, which has a purity of 90 mass % or higher, has a crystallite size of 90 ? or longer and 400 ? or shorter, and is represented by the formula Na3-xMPO4CO3 (M is at least one member selected from the group consisting of Fe, Mn, Ni and Co, and 0?x?2).
    Type: Application
    Filed: May 27, 2020
    Publication date: July 7, 2022
    Applicants: SAGAMI CHEMICAL RESEARCH INSTITUTE, TOSOH CORPORATION
    Inventors: Masaki OKADA, Kennichi TAKAHASHI, Ryoji TANAKA
  • Patent number: 11377725
    Abstract: An oxide sintered body containing indium, hafnium, tantalum, and oxygen as constituent elements, in which when indium, hafnium, and tantalum are designated as In, Hf, and Ta, respectively, the atomic ratio of Hf/(In+Hf+Ta) is equal to 0.002 to 0.030, and the atomic ratio of Ta/(In+Hf+Ta) is equal to 0.0002 to 0.013.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: July 5, 2022
    Assignee: TOSOH CORPORATION
    Inventors: Ryo Akiike, Yuya Tsuchida, Hideto Kuramochi
  • Patent number: 11371982
    Abstract: The purpose of the present invention is to provide a method for accurately predicting a cancer patient prognosis based on a count of desired cells for which expression of a leukocyte marker and an epithelial marker is hardly exhibited by detecting those cells. Provided is a method for diagnosing an overall survival prognosis for a patient suffering from cancer, the method including: a step of obtaining a concentrated solution containing desired cells by pre-treating a biological sample obtained from the patient; a step of optically detecting the concentrated cells; and a step of detecting the desired cells from the detected image, wherein an association is made with the overall survival prognosis diagnosis by counting the detected desired cells, and wherein the desired cells are cells confirmed by the existence of a cell nucleus and in which expression of a leukocyte marker and an epithelial marker is hardly exhibited.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: June 28, 2022
    Assignees: TOSOH CORPORATION, TOKYO METROPOLITAN GOVERNMENT
    Inventors: Yasuyuki Akiyama, Atsushi Morimoto, Toru Futami, Fumiaki Koizumi, Takeshi Sawada
  • Publication number: 20220193644
    Abstract: CHA-type zeolite in which the molar ratio of silica to alumina is less than 13, and the content of sodium is 100 ppm or more and 2000 ppm or less is provided. Such a CHA-type zeolite is obtained by a manufacturing method including obtaining a crystallized product by crystallizing a composition which includes a structure-directing agent source containing at least N,N,N-trialkylcyclohexylammonium cation, an alumina source, a silica source, a sodium source, and water and in which the molar ratio of silica to alumina is 20 or less and in which the molar ratio of potassium to sodium is less than 0.05, removing N,N,N-trialkylcyclohexylammonium cation from the crystallized product, and contacting the crystallized product with an ammonium-salt-containing solution having an ammonium concentration of 1 mass percent or more.
    Type: Application
    Filed: December 16, 2021
    Publication date: June 23, 2022
    Applicant: TOSOH CORPORATION
    Inventors: Yoshitaka YAMASAKI, Tomoya ISHIKAWA, Keita NAKAO, Takuya OKADA, Yusuke NARAKI
  • Publication number: 20220178932
    Abstract: An object of the invention is to provide a method for detecting cancer in a simple and highly accurate manner, and a reagent that can be used in the method. A method for detecting cancer (excluding renal cell cancer), which comprises measuring the level of Azurocidin (AZU1) in a sample, in which it is determined that cancer is detected when a measured value exceeds a preset reference value. The cancer is preferably selected from the group consisting of stomach cancer, breast cancer, colorectal cancer, and lung cancer. A reagent containing an antibody that specifically recognizes AZU1 is used in detecting cancer (excluding renal cell cancer).
    Type: Application
    Filed: April 15, 2020
    Publication date: June 9, 2022
    Applicants: JAPANESE FOUNDATION FOR CANCER RESEARCH, OSAKA UNIVERSITY, TOSOH CORPORATION
    Inventors: Koji UEDA, Naomi OHNISHI, Kazutake TSUJIKAWA, Norio NONOMURA, Motohide UEMURA, Kentaro JINGUSHI, Norihisa OHTAKE, Yasutoshi KAWAI
  • Publication number: 20220162127
    Abstract: Provided is at least one of a zirconia sintered body and a method for producing the same. The zirconia sintered body can be used in a wide range of applications compared with ceramic joined bodies of the related art that include transparent zirconia. A zirconia sintered body includes a transparent zirconia portion and an opaque zirconia portion, wherein the zirconia sintered body has a biaxial flexural strength of greater than or equal to 300 MPa.
    Type: Application
    Filed: March 24, 2020
    Publication date: May 26, 2022
    Applicant: TOSOH CORPORATION
    Inventors: Takeshi ITO, Shoichi YAMAUCHI, Isao YAMASHITA
  • Publication number: 20220153582
    Abstract: A sputtering target for a gallium nitride thin film, which has a low oxygen content, a high density and a low resistivity. A gallium nitride powder having powder physical properties of a low oxygen content and a high bulk density is used and hot pressing is conducted at high temperature in high vacuum to prepare a gallium nitride sintered body having a low oxygen content, a high density and a low resistivity.
    Type: Application
    Filed: February 1, 2022
    Publication date: May 19, 2022
    Applicant: TOSOH CORPORATION
    Inventors: Masami MESUDA, Hideto KURAMOCHI
  • Publication number: 20220149258
    Abstract: Provided is a silicide-based alloy material with which environmental load can be reduced and high thermoelectric conversion performance can be obtained. Provided is a silicide-based alloy material including silicon and ruthenium as main components, in which when the contents of silicon and ruthenium are denoted by Si and Ru, respectively, the atomic ratio of the devices constituting the alloy material satisfies the following: 45 atm %?Si/(Ru+Si)?70 atm % 30 atm %?Ru/(Ru+Si)?55 atm %.
    Type: Application
    Filed: January 15, 2020
    Publication date: May 12, 2022
    Applicant: TOSOH CORPORATION
    Inventors: Yoichiro KODA, Ryo AKIIKE, Hideto KURAMOCHI
  • Publication number: 20220135401
    Abstract: Provided is a core/shell composite that includes a core portion containing a heat resistant material selected from an inorganic oxide, a ceramic, a mineral and the like and having rigidity, and at least one layer of shell portion containing a hydrogen absorbing/desorbing metal covering the entire or a part of the core portion. The heat resistant material contained in the core portion has a melting point higher than the highest melting point among the hydrogen absorbing/desorbing metal contained in the shell portion. In a method for producing the core/shell composite, the core portion is covered with the shell portion by deposition in the absence of oxygen.
    Type: Application
    Filed: February 20, 2020
    Publication date: May 5, 2022
    Applicant: TOSOH CORPORATION
    Inventor: Atsushi MIYAZAWA
  • Publication number: 20220106480
    Abstract: This invention has an object to provide: a resin composition excellent in impact resistance, flexibility, and recyclability obtained as a result of blending a specific ethylene-vinyl acetate copolymer composition with a brittle resin, a recycled resin, or a composite resin including two or more kinds of different resins mixed therein; and a molded article produced with use of the resin composition. The resin composition includes: a thermoplastic resin (A) in an amount of not less than 1 weight % and not more than 99 weight %; and an ethylene-vinyl acetate copolymer composition (B) in an amount of not less than 1 weight % and not more than 99 weight %, the ethylene-vinyl acetate copolymer composition (B) including two or more kinds of ethylene-vinyl acetate copolymers having different vinyl acetate contents, the total amount of (A) and (B) being 100 weight %.
    Type: Application
    Filed: January 20, 2020
    Publication date: April 7, 2022
    Applicant: TOSOH CORPORATION
    Inventors: Daisuke KUGIMOTO, Daisuke KAWATO, Shingo KOUDA
  • Patent number: 11291979
    Abstract: Provided is a ?-zeolite that has an SiO2/Al2O3 ratio of less than 20 but yet is comparable or superior in heat resistance to conventional ?-zeolites having SiO2/Al2O3 ratio of 20 or greater. This ?-zeolite is characterized in that: in powder X-ray diffractometry using a CuK?-ray as a ray source, the full width at half maximum of a powder X-ray diffraction peak on the (302) plane is 0.15-0.50 inclusive; and the molar ratio of silica to alumina is less than 20.0. Preferably, the ?-zeolite is obtained by a production method which comprises a crystallization step for crystallizing a composition comprising an alumina source, a silica source, an alkali source, a tetraethylammonium cation source and water, characterized in that the composition contains potassium and the molar ratio of potassium to silica exceeds 0.04.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: April 5, 2022
    Assignee: TOSOH CORPORATION
    Inventors: Ning Chen, Yusuke Naraki
  • Publication number: 20220056006
    Abstract: A method of stabilizing perfluoro(2-methylene-4-methyl-1,3-dioxolane) (hereinafter simply referred to as a “stabilization method”), including incorporating at least one selected from the group consisting of a hydroxy group-containing fluoroaromatic compound represented by General Formula (1) below and a hydroxy group-containing fluoroaromatic compound represented by General Formula (2) below into a composition containing perfluoro(2-methylene-4-methyl-1,3-dioxolane): (in the formula, R1 to R6 each independently represent one selected from the group consisting of a fluorine atom, a perfluoroalkyl group and a hydroxy group, and at least one of R1 to R6 is a hydroxy group); (in the formula, R7 to R14 each independently represent one selected from the group consisting of a fluorine atom, a perfluoroalkyl group and a hydroxy group, and at least one of R7 to R14 is a hydroxy group).
    Type: Application
    Filed: December 20, 2019
    Publication date: February 24, 2022
    Applicants: TOSOH CORPORATION, TOSOH FINECHEM CORPORATION
    Inventors: Hideki MIYAUCHI, Shota NISHIDA, Daisuke INOUE, Yusuke SHIGETA, Norihisa KONDO, Makoto WATANABE, Shohei YUMINO, Tomoya SHIMONO