Patents Assigned to Tosoh Corporation
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Publication number: 20250026784Abstract: An antibody separation method including a step of applying a solution containing an antibody to a column filled with an antibody adsorption material containing an insoluble porous carrier and an Fc-binding protein immobilized on the carrier and adsorbing the antibody onto the antibody adsorption material; and a step of applying a buffer solution to the column and eluting the antibody adsorbed onto the antibody adsorption material with a pH gradient, wherein the pH gradient is a step gradient in which a pH of the buffer solution is lowered in steps, and wherein the magnitude of pH decrease is 0.1 or more and less than 1.Type: ApplicationFiled: November 14, 2022Publication date: January 23, 2025Applicant: TOSOH CORPORATIONInventors: Yuta HAYAKAWA, Naomasa TANIGUCHI, Yosuke TERAO
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Publication number: 20250011590Abstract: There has been a demand for an optical film having excellent glass-range photoelastic coefficient and a polarizing plate which uses this optical film. The present invention provides an optical film which is characterized by containing an ester-based resin that contains 50% by mole or more of a fumaric acid ester residue unit represented by formula (1) and having a negative birefringence, and a photoelasticity regulator having a positive birefringence, and which is also characterized in that the absolute value of the glass-range photoelastic coefficient thereof is 5×10?12 Pa?1 or less. (In the formula, each of R1 and R2 independently represents a linear alkyl group having 1 to 12 carbon atoms, a branched alkyl group having 3 to 12 carbon atoms, or a cyclic alkyl group having 3 to 6 carbon atoms.Type: ApplicationFiled: November 16, 2022Publication date: January 9, 2025Applicant: TOSOH CORPORATIONInventors: Takuya KOMINE, Asuka YOSHIMURA, Takahiro KITAGAWA
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Publication number: 20250002543Abstract: An immunoglobulin-binding protein has an improved chemical stability, especially having an improved alkaline stability, or an immunoglobulin-binding protein capable of allowing antibody elution under mild pH conditions, and an adsorbent on which the protein is immobilized. The alkaline stability or the antibody elution property is improved by including an amino acid sequence which is the same as an amino acid sequence of an immunoglobulin-binding domain of protein L derived from a bacterium belonging to the genus Finegoldia except that the amino acid residue(s) at a particular position(s) of the domain in the amino acid sequence is/are substituted with another particular amino acid residues(s).Type: ApplicationFiled: October 24, 2022Publication date: January 2, 2025Applicant: TOSOH CORPORATIONInventors: Takatoshi HASEMI, Akihiro IWASE, Satoshi ENDO, Toru TANAKA
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Publication number: 20240425620Abstract: The present invention provides a resin which enables the production of an organic field effect transistor element which has excellent resistance to bias stress by being used as a gate insulating film layer for an organic field effect transistor. The present invention provides a resin which comprises a repeating unit represented by Formula (1) and a repeating unit represented by Formula (2), wherein: the repeating unit represented by Formula (2) has a HOMO level of ?6.4 eV or less; and 20% by mole or more of the repeating unit represented by Formula (2) is contained relative to the total amount of the repeating unit represented by Formula (1) and the repeating unit represented by Formula (2).Type: ApplicationFiled: October 24, 2022Publication date: December 26, 2024Applicant: TOSOH CORPORATIONInventors: Yuta IIJIMA, Shohei YUMINO, Takashi FUKUDA, Rei SHIWAKU, Shinya OKU
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Patent number: 12174194Abstract: A method of collecting and detecting a tumor cell contained in a sample in distinction from a contaminant cell is provided. The tumor cell contained in the sample are collected and detected in distinction from the contaminant cell by detecting any of the following polypeptides or a gene encoding the polypeptide present in the sample: (i) a polypeptide containing at least the amino acid sequence of any of six sequences such as TM4SF1 (GenBank No. NP_055035.1) and TNFRSF12A (GenBank No. NP_057723.1); (ii) a polypeptide containing at least an amino acid sequence having a homology of not less than 70% to the amino acid sequence described above; and (iii) a polypeptide containing at least a splicing variant of the amino acid sequence (the amino acid sequence of (i) or (ii) described above).Type: GrantFiled: February 27, 2019Date of Patent: December 24, 2024Assignee: TOSOH CORPORATIONInventors: Yuichi Kumaki, Sayaka Hirai, Makoto Otsuki, Daisuke Miki, Toru Futami
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Patent number: 12173398Abstract: A Cr—Si sintered body contains Cr and Si. The Cr—Si sintered body contains a crystalline CrSi2 phase and a crystalline Si phase. A content of the Si phase in the Cr—Si sintered body is 40% by mass or more. A relative density of the Cr—Si sintered body relative to a true density of the Cr—Si sintered body is 95% or more. The CrSi2 phase has an average crystal grain size of 40 ?m or less, and the Si phase has an average crystal grain size of 30 ?m or less. A total content of impurities in the Cr—Si sintered body is 200 ppm by mass or less, and the impurities are composed of at least one element selected from the group consisting of Mn, Fe, Mg, Ca, Sr, and Ba.Type: GrantFiled: March 24, 2021Date of Patent: December 24, 2024Assignee: TOSOH CORPORATIONInventors: Hiroyuki Hara, Masami Mesuda, Ayaka Masuda
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Publication number: 20240409471Abstract: A zirconia powder including 2% by mole or more and 8% by mole or less of a stabilizing element and 50 ppm or less of titanium (Ti) and having an activation energy of 225 kJ/mol or more and 300 kJ/mol or less, which provides a zirconia powder capable of producing a sintered body with high translucency even by pressureless sintering and suitable for industrial production, a method for producing the zirconia powder, a method for producing a calcined body using the zirconia powder, and a method for producing a sintered body using the zirconia powder. Such a powder is produced by a method including adjusting a pH of a raw material solution containing a zirconium source and a stabilizing element source to 3.5 or more and 5.5 or less; heating the raw material solution to produce a zirconia sol solution; mixing the zirconia solution and an alkaline solution; and heat-treating.Type: ApplicationFiled: November 24, 2022Publication date: December 12, 2024Applicant: TOSOH CORPORATIONInventors: Koji MATSUI, Kenji IMAI, Kohei HOSOI
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Publication number: 20240400826Abstract: There are provided a polyarylene sulfide composition that contains a post-consumer recycled polyamide and a fibrous filler without compromising the intrinsic heat resistance, chemical resistance, flowability and other characteristics of a polyarylene sulfide and a method for producing it. The polyarylene sulfide composition comprises a polyarylene sulfide (A) having a melt viscosity of 100 to 3000 poises as measured under the conditions of a measuring temperature of 315° C. and a load of 10 kg using a capillary rheometer flow tester fitted with a 1-mm diameter and 2-mm long die, 10 to 90 parts by weight of a post-consumer recycled polyamide (B) per 100 parts by weight of the polyarylene sulfide (A) and 20 to 110 parts by weight of a fibrous filler (C) per a total of 100 parts by weight of the polyarylene sulfide (A) and the post-consumer recycled polyamide (B).Type: ApplicationFiled: October 14, 2022Publication date: December 5, 2024Applicant: TOSOH CORPORATIONInventors: Takeshi HARUNARI, Hiroki INOUE
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Publication number: 20240407260Abstract: Provided are a material for a light receiving element having excellent hole transport characteristics, and an organic light receiving element using the same. A material for a light receiving element is used that includes a compound represented by general formula (1) or general formula (2). Ar2 and Ar3 are preferably cyano groups. Ar and Ar5 are preferably cyano groups.Type: ApplicationFiled: June 28, 2022Publication date: December 5, 2024Applicant: TOSOH CORPORATIONInventors: Nobumichi ARAI, Takeshi OKADA, Yasuhiro TAKAHASHI, Keisuke NOMURA
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Publication number: 20240393349Abstract: Provided are a method of simply detecting Alzheimer's disease (AD) and a method of simply stratifying AD pathological phases, and a reagent that can be used for the methods, based on the fact that measurement of a protein contained in extracellular vesicles enables detection of Alzheimer's disease and stratification of AD pathological phases.Type: ApplicationFiled: September 8, 2022Publication date: November 28, 2024Applicants: TOSOH CORPORATION, JAPANESE FOUNDATION FOR CANCER RESEARCHInventors: Kohei YUYAMA, Yukifusa IGETA, Koji UEDA
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Publication number: 20240382928Abstract: It is an object of the present disclosure to provide a YFl-type zeolite with a small difference in desorption starting temperature due to hydrothermal durability treatment, a method for producing the YFl-type zeolite, a hydrocarbon adsorbent containing the YFl-type zeolite and a hydrocarbon adsorption method using the YFl-type zeolite The YFl-type zeolite is characterized in that the ratio of the mass of extra-framework aluminum to the mass of contained aluminum is 0% by mass or more and 28% by mass or less.Type: ApplicationFiled: May 31, 2022Publication date: November 21, 2024Applicant: TOSOH CORPORATIONInventors: Ryo MITSUHASHI, Naoto NAKAZAWA, Toyohiro USUI
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Publication number: 20240376012Abstract: Provided is a powder composition that includes, as a matrix, a zirconia having a high content of a stabilizing element and that can provide, through short-time sintering, a sintered body satisfying translucency and mechanical strength required for dental prosthetic materials, in particular, prosthetic anterior teeth. Provided is a powder composition including two or more stabilized zirconias having different contents of a stabilizing element, in which the powder composition has a content of the stabilizing element of more than 4.0 mol % and 5.8 mol % or less, a rate of change in thermal shrinkage rate per unit temperature at 1,300° C. is 0.07% C?1 or less, and the contents of the stabilizing element of the stabilized zirconias are each 8.0 mol % or less.Type: ApplicationFiled: September 15, 2022Publication date: November 14, 2024Applicant: TOSOH CORPORATIONInventors: Sho AZECHI, Yuya HIGUCHI, Hiroyuki FUJISAKI, Hitoshi NAGAYAMA, Kiyotaka KAWAMURA
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Patent number: 12134677Abstract: The present invention relates to a hydrophilizing agent for producing a self-emulsifying polyisocyanate composition, the hydrophilizing agent comprising an anionic compound represented by the following formula (1): wherein X represents a sulfo group or a hydroxysulfonyloxy group, R1 represents a straight-chain or branched alkylene group, and R2 represents a straight-chain or branched alkyl group; the total number of carbon atoms included in R1 and R2 is 6 or more and less than 14, and one or two or more carbon atoms in the groups R1 and R2 are optionally replaced with an oxygen atom(s).Type: GrantFiled: February 26, 2019Date of Patent: November 5, 2024Assignees: TOSOH CORPORATION, SAGAMI CHEMICAL RESEARCH INSTITUTEInventors: Motomu Kita, Shimou Chinson, Munenori Inoue, Masahiro Nagaoka, Hiroaki Adachi, Aki Maeda
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Patent number: 12134584Abstract: Disclosed is a coating layer-bonded continuous ceramic fiber formed from a continuous ceramic fiber having a coating layer of a metal compound with a thickness of 50 nm or less on the surface. Also disclosed is a ceramic matrix composite material having the above-described coating layer-bonded continuous ceramic fiber.Type: GrantFiled: March 24, 2020Date of Patent: November 5, 2024Assignee: TOSOH CORPORATIONInventors: Isao Yamashita, Yushi Nawata
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Publication number: 20240359375Abstract: A metal member-polyarylene sulfide resin member composite having an air-tight joint between the metal member and the polyarylene sulfide resin member and a method for its production are provided. A metal member-polyarylene sulfide resin member composite comprising a metal member and a polyarylene sulfide member which is obtained by injection molded direct joining, wherein the polyarylene sulfide member is made of a polyarylene sulfide resin composition which satisfies all of the following (1) to (3): (1) it has a melt crystallization peak temperature of at least 200° C. and at most 230° C., (2) it has an MFR of at least 20 g/10 minutes and at most 150 g/10 minutes, and (3) it comprises 100 parts by weight of a polyarylene sulfide resin (A), from 5 to 25 parts by weight of a modified ethylene copolymer (B) and from 10 to 120 parts by weight of glass fiber (C).Type: ApplicationFiled: August 3, 2022Publication date: October 31, 2024Applicant: TOSOH CORPORATIONInventor: Takeshi HARUNARI
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Patent number: 12110304Abstract: Provided are a divalent phosphazenium salt which is neutral and is excellent in thermal stability and aldehyde scavenging ability, and a method for producing the same. Also provided are a polyalkylene oxide composition having a volatile aldehyde amount reduced, having generation of odor and turbidity suppressed and being excellent in urethanization reactivity, and a method for producing such a polyalkylene oxide composition, as well as a polyurethane-forming composition containing the polyalkylene oxide composition. A divalent phosphazenium salt having a specific structure. Also, a polyalkylene oxide composition comprising a divalent phosphazenium salt having a specific structure and a polyalkylene oxide, a method for producing the same, and a polyurethane-forming composition containing the same.Type: GrantFiled: March 5, 2019Date of Patent: October 8, 2024Assignee: TOSOH CORPORATIONInventors: Yoshiaki Inoue, Toshihide Yamamoto, Katsuaki Mori
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Patent number: 12104007Abstract: An allophanate group-containing polyisocyanate composition that contributes to the formation of a polyurethane resin with fewer bubbles is provided. Disclosed is an allophanate group-containing polyisocyanate composition (C) including a reaction product of diphenylmethane diisocyanate (A) and a hydroxyl group-containing compound (B), wherein the hydroxyl group-containing compound (B) includes a hydroxyl group-containing polymethylsiloxane compound (B-1) in an amount of 1 ppm or more and 300 ppm or less.Type: GrantFiled: July 24, 2019Date of Patent: October 1, 2024Assignee: TOSOH CORPORATIONInventors: Mitsushige Ikemoto, Futoshi Oota
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Patent number: 12101991Abstract: Provided are (i) a solution for forming an organic semiconductor layer which solution has excellent coating property, (ii) an organic semiconductor which is produced with use of the solution and which has high heat resistance, (iii) a layer which contains the organic semiconductor, and (iv) an organic thin film transistor which exhibits high electrical properties. A composition containing: an organic semiconductor; and a polymer (1) having at least one unit selected from the group consisting of units represented by formulae (1-a), (1-b) and (1-c) given below. A composition containing the organic semiconductor, the polymer (1) and an organic solvent can be suitably used as a solution for forming an organic semiconductor layer.Type: GrantFiled: December 19, 2019Date of Patent: September 24, 2024Assignee: TOSOH CORPORATIONInventors: Takahiro Mori, Takashi Fukuda
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Publication number: 20240308195Abstract: A stretched polyethylene film for lamination, which comprises a polyethylene (A) having a weight average molecular weight (Mw) as measured by gel permeation chromatography of from 70,000 to 250,000, a proportion of fractions with a molecular weight of 10,000 or less of 8 wt % or less, and a density as measured in accordance with JIS K6922-1 (1997) of from 945 to 980 kg/m3, and has at least one peak in a range of 135° C. or higher in an endothermic curve as measured by differential scanning calorimetry, the film having high recyclability and excellent in heat resistance.Type: ApplicationFiled: February 18, 2022Publication date: September 19, 2024Applicant: TOSOH CORPORATIONInventors: Shingo KOUDA, Shoji NISHIO, Kenichi SUZUKI
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Publication number: 20240301197Abstract: In regard to a conventionally known resin composition for an antistatic hard coating to which an ionic liquid is added and an antistatic hard coating using it, there is a problem that it is difficult to achieve both an antistatic ability and high hardness. In order to solve the problem, used is a resin composition for an ultraviolet curing hard coating, the resin composition containing: an electrically conductive polymer that contains polythiophene (A) including at least two structural units represented by a specific general formula; an ultraviolet curable resin (B); and a solvent (C).Type: ApplicationFiled: March 4, 2024Publication date: September 12, 2024Applicant: TOSOH CORPORATIONInventors: Haruka AOKI, Sadayoshi HAYASHI, Hirokazu YANO, Hirofumi MIYAKE