Abstract: The present invention aims to provide a method for detecting, with high sensitivity and specificity, ovarian clear cell adenocarcinoma, which is highly malignant, among benign and malignant ovarian tumors having various tissue types, and a reagent that can be used for the method. The present invention provides NT-TFPI2, which is a novel processed tissue factor pathway inhibitor 2 polypeptide, as a new detection marker for ovarian clear cell adenocarcinoma. The detection of ovarian clear cell adenocarcinoma is carried out by measuring the amount of NT-TFPI2, or the total amount of NT-TFPI2 and intact TFPI2. The reagent for detecting ovarian clear cell adenocarcinoma contains an antibody that specifically recognizes NT-TFPI2 and intact TFPI2.
Type:
Application
Filed:
November 26, 2015
Publication date:
November 9, 2017
Applicants:
PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY, TOSOH CORPORATION
Abstract: An azine compound represented by the formula (1), a method for its production and an organic electroluminescent device containing it as a constituent component. wherein Ad each independently represents a 1-adamantyl group, etc., p and q are each independently 0 or 1, Ar1 and Ar2 are each independently a single bond (but only when p is 1, or q is 1), or a pyridyl group which may be substituted by a phenyl group, etc., incidentally, Ad groups on Ar1 and Ar2 are each independently bonded to said pyridyl group, etc., Ar2 is each independently a C3-13 heteroaromatic group which may be substituted by a fluorine atom, etc., X1, X2, X3 and X4 are each independently a single bond, etc., m and n are each independently 0, 1 or 2, Z is a nitrogen atom, etc., n+p+q is 1, 2 or 3.
Abstract: A novel MFI zeolite that when used as a catalyst, can be used for a selective catalytic reaction for larger molecules and provides a method for producing the MFI zeolite. The MFI zeolite includes uniform mesopores having a pore distribution curve which a peak-width thereof at half height (hw) is at most 20 nm (hw?20 nm) and a center value (?) of a maximum peak is 10 nm or more and 20 nm or less (10 nm???20 nm), and having a pore volume (pv) of the uniform mesopores of at least 0.05 mL/g (0.05 mL/g?pv); the MFI zeolite has no peak in a range of 0.1° to 3° in powder X-ray diffraction measurement with a diffraction angle represented by 2?; and the MFI zeolite has an average particle diameter (PD) of at most 100 nm (PD?100 nm).
Abstract: To provide an amine catalyst for curing a polyisocyanate which can satisfy both initial moldability before a thermal compression step and high reactivity at the time of thermal compression molding, and an adhesive composition containing it. A catalyst comprising an amine compound (1) represented by the formula (1) and an amine compound (2) represented by the formula (2) is used as an amine catalyst for curing a polyisocyanate compound. wherein each of R1 and R2 which are independent of each other, is a C1-4 hydrocarbon group, and R3 is a C1-4 hydrocarbon group having a hydroxy group or an amino group; wherein each of R4 and R5 which are independent of each other, is a C1-4 hydrocarbon group, R6 is a C1-4 hydrocarbon group or a C1-4 hydrocarbon group having a hydroxy group or an amino group, R7 is a C1-4 hydrocarbon group having a hydroxy group or an amino group, and m is an integer of from 2 to 6.
Abstract: A novel heterocyclic compound for an organic electroluminescent device excellent in long service life and light-emitting characteristics is provided. A cyclic azine compound has at least one substituent (substituent B) selected from a specific group.
Abstract: A resin composition suitable for an optical compensation film, an optical compensation film using the same, which is excellent in the retardation characteristics and wavelength dispersion characteristics, and a production method of an optical compensation film. A resin composition containing, as resin components, from 30 to 99 wt % of a cellulose-based resin represented by the following formula (1) and from 1 to 70 wt % of a cinnamic acid ester copolymer: where each of R1, R2 and R3 independently represents hydrogen or a substituent having a carbon number of 1 to 12.
Abstract: To provide a zirconia sintered body having both excellent translucency and bending strength, specifically a zirconia sintered body having both translucency and strength suitable as a denture for front tooth, and a process for its production. A translucent zirconia sintered body containing more than 4.0 mol % and at most 6.5 mol % of yttria and less than 0.1 wt % of alumina, and having a relative density of at least 99.82%, a total light transmittance of at least 37% and less than 40% to light with a wavelength of 600 nm at a thickness of 1.0 mm, and a bending strength of at least 500 MPa, and a process for its production.
Abstract: Provided are: a polyethylene laminate that exhibits excellent flexibility, barrier properties, and cleanliness (a low occurrence of fine particles), that does not deform even after sterilization treatment at 121° C., and that maintains high transparency; and a medical container using same. The medical container is configured by layering: an outer layer and an inner layer that comprise from 20 to 80 wt % of a high-density polyethylene (A) having specific properties, from 0 to 50 wt % of a linear low-density polyethylene (B1), and from 5 to 40 wt % of an ethylene-based polymer (C); and an intermediate layer that comprises from 10 to 40 wt % of the high-density polyethylene (A) and from 60 to 90 wt % of the linear low-density polyethylene (B1).
Abstract: To provide a catalyst composition excellent in cell openness properties and initial curing properties, and a method for producing a polyurethane resin using the same. A catalyst composition comprising an amine compound (A) of the formula (1), a hydroxy acid (B) of the formula (2) and a tertiary amine compound (C) is used for the production of a polyurethane resin. [Each of R1 and R2 which are independent of each other, is a methyl group or an ethyl group, R3 is a C2-4 linear or branched alkyl group, R4 is a C1-18 bivalent hydrocarbon residue, m is an integer of from 1 to 3, and n is an integer of from 1 to 6.
Abstract: Provided are: an Fc-binding protein having improved stability, particularly to heat and acid; a method for producing the protein; an antibody adsorbent using the protein; and a method for separating the antibodies using the adsorbent. Specifically provided are: an Fc-binding protein having improved stability to heat and acid, achieved by substituting an amino-acid residue in a specific position in the extracellular region of human FcyRIIIa with another specific amino acid; a method for producing the protein; an antibody adsorbent using the protein; and a method for separating the antibodies using the adsorbent.
Abstract: To provide a water-soluble polythiophene used as an electrically conductive material, and its production method. A polythiophene comprising at least one type of structural units selected from the group consisting of structural units represented by the formula (1), structural units represented by the formula (2), structural units represented by the formula (3), structural units represented by the formula (4), structural units represented by the formula (5) and structural units represented by the formula (6). The polythiophene is obtained by polymerizing at least one thiophene compound selected from the group consisting of a thiophene compound represented by the formula (15), a thiophene compound represented by the formula (16) and a thiophene compound represented by the formula (17) in water or an alcohol solvent in the presence of an oxidizing agent.
Abstract: Provided are: an isocyanate composition for producing a flexible foam that has good vibration absorption as a result of having a low rebound resilience rate and a low hysteresis loss rate even in a low-density area; a composition for forming a flexible foam in which the isocyanate composition is used; and a flexible foam production method in which the composition for forming a flexible foam is used. The composition for forming a flexible foam has a low hysteresis loss rate and high durability in a high hardness range and in a low density range. The flexible foam production method uses this composition for forming a flexible foam. The flexible foam production method does not cause odor problems or the like, maintains the durability required of a flexible foam even when the density thereof is reduced, and achieves good riding comfort properties and high safety.
Abstract: The purpose of the present invention is to provide a sintered oxide to be used for a sputtering target, whereby little abnormal discharge occurs even during high-power film-deposition and no cracking occurs in the target. A sintered oxide having zinc, aluminum, titanium and oxygen, as constituent elements, characterized in that when the contents of zinc, aluminum and titanium are represented by Zn, Al, and Ti, respectively, the atomic ratios of the elements constituting the sintered oxide are Al/(Zn+Al+Ti)=0.035 to 0.050 and Ti/(Zn+Al+Ti)=0.05 to 0.20, and the average grain size of crystal grains having a Zn2TiO4 crystal phase as the matrix phase in the sintered oxide, is at most 5 ?m.
Abstract: To provide a novel amine compound which is especially suitable for a hole transport material for organic EL devices, and an organic EL device which employs such an amine compound and is excellent in the driving voltage, luminous efficiency and device lifetime An amine compound represented by the formula (1): (wherein X is a sulfur atom or an oxygen atom, each of R1 to R10 which are independent of one another, is a hydrogen atom, a deuterium atom or a phenyl group, and each of Ar1 and Ar2 which are independent of each other, is a C6-18 aromatic hydrocarbon group, a dibenzothienyl group or a dibenzofuranyl group, which, each independently, may have a substituent consisting of a methyl group, a methoxy group, a dibenzothienyl group, a dibenzofuranyl group or a 9-carbazolyl group.).
Abstract: To provide a heterogeneous catalyst that exhibits high activity and high selectivity, specifically a catalyst suitable for oxychlorination to produce 1,2-dichloroethane from ethylene, and a catalyst system. Provided are: a heterogeneous catalyst supported on a porous carrier, characterized in that the integral value of the hysteresis occurring between an adsorption isotherm and a desorption isotherm by a gas adsorption method, is at most 19% to the total integral value of the adsorption isotherm; and a catalyst system for producing 1,2-dichloroethane, which comprises this catalyst and a diluent having a spherical shape, circular cylindrical shape or hollow cylindrical shape.
Abstract: To provide opaque quartz glass having no water absorbing properties and being excellent in infrared light shielding properties, and a method for its production. In the production of opaque quartz glass of the present invention, a fine amorphous silica powder and a pore forming agent are mixed, then molded and heated at a predetermined temperature, to obtain opaque quartz glass wherein contained pores are closed pores, the average pore size of pores is from 5 to 20 ?m, and the content density of pores is high, whereby the heat shielding properties are high.
Abstract: The present invention provides a composition that includes a silicotitanate that has a sitinakite structure, the composition having higher cesium adsorptivity than conventional compositions. The present invention also provides a production method for the composition that includes a silicotitanate that has a sitinakite structure. The production method does not require the use of hazardous or deleterious materials, can generate a product using a compound that is easily acquired, and can use a general-purpose autoclave. Also provided is a silicotitanate composition that has higher strontium adsorptivity than the present invention. Provided is a silicotitanate composition that contains niobium and a silicotitanate that has a sitinakite structure, the composition having at least two or more diffraction peaks selected from the group consisting of 2?=8.8°±0.5°, 2?=10.0°±0.5°, and 2?=29.6°±0.5°.
Abstract: The invention relates to: a ?-type iron silicate which has a fluorine content not more than 400 ppm by weight on a dry basis and in which the crystal grains have a truncated square bipyramidal morphology in an examination with a scanning electron microscope and the whole or part of the iron is contained in the ?-type framework structure, and a process for producing the iron silicate; anther ?-type iron silicate, and a process for producing the iron silicate; and a nitrogen oxide removal catalyst containing the other ?-type iron silicate, a process for producing the catalyst, and a method for nitrogen oxide removal with the catalyst.
Type:
Grant
Filed:
December 21, 2010
Date of Patent:
June 13, 2017
Assignee:
TOSOH CORPORATION
Inventors:
Yusuke Naraki, Keisuke Tokunaga, Ko Ariga
Abstract: A compound useful for the manufacture of a Group 5 metal oxide film is provided. The compound is a Group 5 metal oxo-alkoxo complex represented by the following formula (A), and after preparing a film-forming material solution containing the compound and an organic solvent, a Group 5 metal oxide film can be manufactured using the film-forming material solution: M?(?4-O)?(?3-O)?(?-O)?(?-ORA)?(ORA)?(RAOH)?X?Y???(A) (wherein M represents a niobium atom, etc.; RA represents an alkyl group; X represents an alkylenedioxy group; Y represents a carboxy group, etc.; ? represents an integer of 3 to 10; ? represents 0 or 1; ? represents an integer of 0 to 8; ? represents an integer of 2 to 9; ? represents an integer of 0 to 6; ? represents an integer of 6 to 16; ? represents an integer of 0 to 4; ? represents an integer of 0 to 2; and ? represents an integer of 0 to 6).
Type:
Grant
Filed:
December 27, 2013
Date of Patent:
May 30, 2017
Assignees:
TOSOH CORPORATION, Sagami Chemical Research Institute
Abstract: A zirconia sintered body is provided having a color tone equivalent to the color tone guides of various natural teeth and having the same aesthetics as a natural front tooth. The present invention provides a colored translucent zirconia sintered body comprising zirconia containing greater than 4.0 mol % and not greater than 6.5 mol % of yttria, less than 0.25 mol % of erbia, less than 2,000 ppm of iron oxide in terms of Fe2O3, less than 0.01 wt. % of cobalt oxide in terms of CoO, and less than 0.1 wt. % of alumina; the zirconia sintered body having a relative density of not less than 99.90%, a total light transmittance of not less than 25% and less than 40% for light having a wavelength of 600 nm at a sample thickness of 1.0 mm, and a strength of not less than 500 MPa.