Patents Assigned to Total Synthesis, Ltd.
  • Transition metal complexes of N-heterocyclic carbenes, method of preparation and use in transition metal catalyzed organic transformations
    Patent number: 7250510
    Abstract: The present invention relates to catalysts of transition metal complexes of N-heterocyclic carbenes, their methods of preparation and their use in chemical synthesis. The synthesis, ease-of-use, and activity of the compounds of the present invention are substantial improvements over in situ catalyst generation. Further, the transition metal complexes of N-heterocyclic carbenes of the present invention may be used as precatalysts in metal-catalyzed cross-coupling reactions.
    Type: Grant
    Filed: August 23, 2006
    Date of Patent: July 31, 2007
    Assignee: Total Synthesis, Ltd.
    Inventors: Michael G. Organ, Christopher J. O'Brien, Assam (Eric) B. Kantchev
  • Transition metal complexes of N-heterocyclic carbenes, method of preparation and use in transition metal catalyzed organic transformations
    Publication number: 20070073055
    Abstract: The present invention relates to catalysts of transition metal complexes of N-heterocyclic carbenes, their methods of preparation and their use in chemical synthesis. The synthesis, ease-of-use, and activity of the compounds of the present invention are substantial improvements over in situ catalyst generation. Further, the transition metal complexes of N-heterocyclic carbenes of the present invention may be used as precatalysts in metal-catalyzed cross-coupling reactions.
    Type: Application
    Filed: August 23, 2006
    Publication date: March 29, 2007
    Applicant: Total Synthesis, Ltd.
    Inventors: Michael Organ, Christopher O'Brien, Assam (Eric) Kantchev