Abstract: The invention relates to a foolproofing device (12) equipped with pins (14-1 and 14-2) placed around the neck of a container (10), the container containing a product for pharmaceutical, medical or other use intended to be used by an extraction system (30) screwed onto a threaded support which may be the neck of the container itself or a sleeve (16) placed on the neck of the container, the screwing operation and thus the use of the product by the extraction system being possible only if the notches (34-1 and 34-2) of the extraction system coincide with the pins of the foolproofing device. According to a main characteristic of the invention, the foolproofing device (12) is characterized in that it is integral with the threaded support (16) of the container by means of connecting parts (18) between the foolproofing device and the threaded support, the connecting parts being broken when the extraction system coinciding with the foolproofing device is screwed onto the threaded support of the container.