Patents Assigned to Tower Laboratories, Ltd.
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Publication number: 20220192990Abstract: Tablets are prepared with friability reducing agents to yield tablets that are more resistant to breakage or crumbling, but with satisfactory hardness. The friability reducing agents include low molecular weight polyethylene glycol as well as similar agents exhibiting at least three percent (3%) hydroxide moieties and a water solubility of at least eighty percent (80%) (w/w %) in room temperature water. The tablets may comprise an active agent and excipient of almost any type, and about 0.1-about 0.5% by weight friability reducing agent. They exhibit a hardness of at least eighty percent (80%) of the same tablet prepared without the friability reducing agent.Type: ApplicationFiled: March 10, 2022Publication date: June 23, 2022Applicant: TOWER LABORATORIES LTDInventors: Allen Rau, Donald Stadolnik, Mevin Corcino, Freddy Acosta
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Publication number: 20210308059Abstract: Tablets are prepared with friability reducing agents to yield tablets that are more resistant to breakage or crumbling, but with satisfactory hardness. The friability reducing agents include low molecular weight polyethylene glycol as well as similar agents exhibiting at least three percent (3%) hydroxide moieties and a water solubility of at least eighty percent (80%) (w/w %) in room temperature water. The tablets may comprise an active agent and excipient of almost any type, and about 0.1-about 0.5% by weight friability reducing agent. They exhibit a hardness of at least eighty percent (80%) of the same tablet prepared without the friability reducing agent.Type: ApplicationFiled: June 10, 2021Publication date: October 7, 2021Applicant: TOWER LABORATORIES LTDInventors: Allen Rau, Donald Stadolnik, Mevin Corcino, Freddy Acosta
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Patent number: 11058642Abstract: Tablets are prepared with friability reducing agents to yield tablets that are more resistant to breakage or crumbling, but with satisfactory hardness. The friability reducing agents include low molecular weight polyethylene glycol as well as similar agents exhibiting at least three percent (3%) hydroxide moieties and a water solubility of at least eighty percent (80%) (w/w %) in room temperature water. The tablets may comprise an active agent and excipient of almost any type, and about 0.1-about 0.5% by weight friability reducing agent. They exhibit a hardness of at least eighty percent (80%) of the same tablet prepared without the friability reducing agent.Type: GrantFiled: April 22, 2013Date of Patent: July 13, 2021Assignee: TOWER LABORATORIES LTDInventors: Allen Rau, Donald Stadolnik, Melvin Corcino, Freddy Acosta
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Patent number: 10022318Abstract: This invention provides an effervescent solid form that dissolves in cold water quickly enough to not disappoint consumers yet not so quickly that the visual interest generated during the effervescent reaction is lost. This performance is achieved by forming effervescent particles that are dense enough to retard dissolution and small enough to not take too long to dissolve. The aim of this invention is to provide a beverage in solid effervescent form that takes between about 30 and about 120 seconds to dissolve in warm water. The granules may carry functional additives such as flavors, vitamins, minerals, sweeteners, colors and drugs. The granules may also be compounded of materials intended to provide relief from skin or topical discomfort, as in the form of a wash or bath additive. The granules may also be formulated to provide cleaning agents, such as ceramic cleaners and denture cleaners.Type: GrantFiled: August 16, 2016Date of Patent: July 17, 2018Assignee: TOWER LABORATORIES, LTD.Inventors: Allen Rau, Nicole Quinn, Donald Stadolnik, Eric Sterner
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Publication number: 20160354306Abstract: This invention provides an effervescent solid form that dissolves in cold water quickly enough to not disappoint consumers yet not so quickly that the visual interest generated during the effervescent reaction is lost. This performance is achieved by forming effervescent particles that are dense enough to retard dissolution and small enough to not take too long to dissolve. The aim of this invention is to provide a beverage in solid effervescent form that takes between about 30 and about 120 seconds to dissolve in warm water. The granules may carry functional additives such as flavors, vitamins, minerals, sweeteners, colors and drugs. The granules may also be compounded of materials intended to provide relief from skin or topical discomfort, as in the form of a wash or bath additive. The granules may also be formulated to provide cleaning agents, such as ceramic cleaners and denture cleaners.Type: ApplicationFiled: August 16, 2016Publication date: December 8, 2016Applicant: TOWER LABORATORIES, LTD.Inventors: ALLEN RAU, NICOLE QUINN, DONALD STADOLNIK, ERIC STERNER
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Patent number: 9457204Abstract: This invention provides an effervescent solid form that dissolves in cold water quickly enough to not disappoint consumers yet not so quickly that the visual interest generated during the effervescent reaction is lost. This performance is achieved by forming effervescent particles that are dense enough to retard dissolution and small enough to not take too long to dissolve. The aim of this invention is to provide a beverage in solid effervescent form that takes between about 30 and about 120 seconds to dissolve in warm water. The granules may carry functional additives such as flavors, vitamins, minerals, sweeteners, colors and drugs. The granules may also be compounded of materials intended to provide relief from skin or topical discomfort, as in the form of a wash or bath additive. The granules may also be formulated to provide cleaning agents, such as ceramic cleaners and denture cleaners.Type: GrantFiled: August 6, 2009Date of Patent: October 4, 2016Assignee: Tower Laboratories, Ltd.Inventors: Allen Rau, Nicole Quinn, Donald Stadolnik, Eric Sterner
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Patent number: 8956652Abstract: Effervescent tablets, powders and granules are provided which may be dissolved in water to produce an effervescent rehydrating beverage. The effervescent tablet, powder and granule compositions of the invention deliver electrolytes and carbohydrates at levels that provide hypotonic, isotonic or slightly hypertonic solution when dissolved in water, with acceptable taste.Type: GrantFiled: September 15, 2005Date of Patent: February 17, 2015Assignee: Tower Laboratories, Ltd.Inventor: Allen H. Rau
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Publication number: 20140315719Abstract: Tablets are prepared with friability reducing agents to yield tablets that are more resistant to breakage or crumbling, but with satisfactory hardness. The friability reducing agents include low molecular weight polyethylene glycol as well as similar agents exhibiting at least three percent (3%) hydroxide moieties and a water solubility of at least eighty percent (80%) (w/w %) in room temperature water. The tablets may comprise an active agent and excipient of almost any type, and about 0.1-about 0.5% by weight friability reducing agent. They exhibit a hardness of at least eighty percent (80%) of the same tablet prepared without the friability reducing agent.Type: ApplicationFiled: April 22, 2013Publication date: October 23, 2014Applicant: TOWER LABORATORIES, LTD.Inventors: ALLEN RAU, Donald STADOLIK, Melvin CORCINO, Freddy ACOSTA
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Patent number: 8206686Abstract: This invention provides a tablet that effervesces and significantly warms the water that it is dissolved in. The effervescence acts to break up the tablet allowing an exothermic material to rapidly dissolve releasing its heat of solution. The invention is unique in that no organic acid is required to form a conventional effervescent couple.Type: GrantFiled: April 17, 2009Date of Patent: June 26, 2012Assignee: Tower Laboratories, Ltd.Inventor: Allen H. Rau
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Patent number: 8192724Abstract: A water soluble, non-abrasive, effervescent, pharmaceutically acceptable, oral care tablet for use in the oral cavity. The tablet includes a carbon dioxide source, a acid source and a tablet forming material admixed to form a chewable tablet having less than 0.2% water. The carbonate to acid ratio ranges from about 2.33:1 to about 3.33:1, the percent by weight of tablet forming material ranges from about 10% to about 70% of the total tablet weight, and the pH of the tablet when dissolved in water to form a 1.0% by weight aqueous solution ranges from about 5.0 to about 7.0. Also included is a flavor imparting flavor agent in an amount sufficient to mask taste sensations derived from the carbon dioxide source, acid source and binder to provide an abrasive-free texture to the tongue in the oral cavity. Other additives are contemplated.Type: GrantFiled: November 2, 2005Date of Patent: June 5, 2012Assignee: Tower Laboratories, Ltd.Inventor: Allen H. Rau
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Patent number: 8007842Abstract: A composition for providing aromatherapy, and in particular, symptomatic relief of nasal and sinus congestion is provided in unit dosage format. The composition includes a penetrating aromatic vapor whose release from a preparation of warm water is augmented by an effervescent component which reacts in the warm water to promote release of the aromatic fragrance, or sustained over time by tableting or gelatin encapsulation. As the fragrance is inhaled, symptomatic relief is obtained. The composition of matter may be rendered ingestible, so that the warm water containing the composition is consumed following inhalation. In preferred embodiments, the release of the penetrating aromatic fragrance persists over time.Type: GrantFiled: April 13, 2007Date of Patent: August 30, 2011Assignee: Tower Laboratories, Ltd.Inventor: Allen H Rau