Abstract: The invention provides structures and methods that allow polymers of any length, including nucleic acids, to be stretched into a long, linear conformation for further analysis.
Abstract: A chamber in which an agent, like genomic DNA, may be harvested and optionally manipulated rapidly (e.g., on the order of a few hours), without shearing or fragmentation.
Type:
Grant
Filed:
January 8, 2008
Date of Patent:
April 7, 2015
Assignee:
Toxic Report LLC
Inventors:
Vishal Patil, Emilia Mollova, Rudolf Gilmanshin
Abstract: The invention provides devices and methods for improving labeling of nucleic acids including intercalation of nucleic acids using for example mono intercalators such as mono cyanine intercalators.