Patents Assigned to TOYO UNIVERSITY
  • Patent number: 11559512
    Abstract: This application provides a composition for preventing, alleviating and/or treating a heat illness, or cytotoxicity of cells such as vascular endothelial cells caused by load of heat stress and/or aberration associated with the production and release of a fever-inducing inflammatory cytokine(s) from blood cells caused by load of heat stress in a subject, comprising at least one substance selected from the group consisting of auraptene, tangeretin, and medium chain fatty acid as an active ingredient.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: January 24, 2023
    Assignee: TOYO UNIVERSITY
    Inventor: Kazunori Kato
  • Patent number: 11427489
    Abstract: [Problem] A carrier for retaining anammox bacteria, an anammox bacteria-adhered particle, and a wastewater treatment apparatus are provided that can remarkably reduce the start-up period for obtaining a nitrogen removal speed of 1 kg-N/m3/day. [Solution] A carrier for retaining anammox bacteria includes carbon particles. The carbon particles are desirably graphite particles, particularly isotropic graphite particles. The carbon particles desirably have a zeta potential of ?35 mV to 0 mV and an average particle size of 2 ?m to 1000 ?m.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: August 30, 2022
    Assignees: TOYO UNIVERSITY, TOYO TANSO CO.. LTD.
    Inventors: Tatsuo Sumino, Satoshi Sakuma, Tetsuro Tojo, Ai Ishikawa, Tomoya Nakazono, Masatoshi Takeshita
  • Publication number: 20220271297
    Abstract: Provided is a fuel cell catalyst composition comprising a C12A7:X? inorganic material having a structure in which oxygen anions of C12A7 are replaced by halogen (X) anions, or comprising a C12A7:X?-based inorganic material which is a C12A7:X? partially converted to electride. A fuel cell comprising the fuel cell catalyst composition in a catalyst layer is also provided. Also provided is a method of producing a fuel cell catalyst composition, comprising a step of heat-treating C12A7:X? at temperature of 1000-1300° C. for at least 20 hours under a nitrogen atmosphere.
    Type: Application
    Filed: July 1, 2020
    Publication date: August 25, 2022
    Applicant: TOYO UNIVERSITY
    Inventor: Noboru WADA
  • Patent number: 10765637
    Abstract: Provided is a composition which can be utilized for drug delivery systems that can penetrate the blood brain barrier, and has low cytotoxicity. A nanoparticle composition comprises nanoparticles to the surface of which a first substance and a second substance each having specificity to a tumor cell are bound, wherein the first substance having specificity to the tumor cell is a peptide comprising an amino acid sequence of arginine-glycine-aspartic acid, and wherein the second substance having specificity to the tumor cell is an iron-binding protein, and wherein the nanoparticles each comprise an outer layer and vesicles enveloped by the outer layer and the nanoparticles each comprise, as membrane components, a PEGylated phospholipid, a fatty acid with a melting point of 30° C. or more, and a non-PEGylated phospholipid.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: September 8, 2020
    Assignee: TOYO UNIVERSITY
    Inventors: Toru Maekawa, Sakthikumar Dasappan Nair, Sheikh Mohamed Mohamed, Srivani Veeranarayanan
  • Publication number: 20190359722
    Abstract: Provided is an antibody specific to EPHA2. A monoclonal antibody specifically binding to EPHA2, comprising a heavy chain variable region consisting of the amino acid sequence as set forth in SEQ ID NO: 20 and a light chain variable region consisting of the amino acid sequence as set forth in SEQ ID NO: 22, or a functional fragment of the monoclonal antibody specifically binding to EPHA2, and a monoclonal antibody specifically binding to EPHA2, comprising a heavy chain variable region consisting of the amino acid sequence as set forth in SEQ ID NO: 15 and a light chain variable region consisting of the amino acid sequence as set forth in SEQ ID NO: 18, or a functional fragment of the monoclonal antibody specifically binding to EPHA2.
    Type: Application
    Filed: January 22, 2018
    Publication date: November 28, 2019
    Applicant: TOYO UNIVERSITY
    Inventors: Kazunori KATO, Toshinori AGATSUMA, Jun HASEGAWA
  • Publication number: 20190099382
    Abstract: Provided is a composition which can be utilized for drug delivery systems that can penetrate the blood brain barrier, and has low cytotoxicity. A nanoparticle composition comprises nanoparticles to the surface of which a first substance and a second substance each having specificity to a tumor cell are bound, wherein the first substance having specificity to the tumor cell is a peptide comprising an amino acid sequence of arginine-glycine-aspartic acid, and wherein the second substance having specificity to the tumor cell is an iron-binding protein, and wherein the nanoparticles each comprise an outer layer and vesicles enveloped by the outer layer and the nanoparticles each comprise, as membrane components, a PEGylated phospholipid, a fatty acid with a melting point of 30° C. or more, and a non-PEGylated phospholipid.
    Type: Application
    Filed: March 23, 2017
    Publication date: April 4, 2019
    Applicant: TOYO UNIVERSITY
    Inventors: Toru MAEKAWA, Sakthikumar DASAPPAN NAIR, Sheikh Mohamed MOHAMED, Srivani VEERANARAYANAN
  • Patent number: 10172542
    Abstract: A motor performance evaluation apparatus 100 for evaluating motor performance of a subject, including: an acquisition unit 131 configured to acquire drawing stroke information including position information and time information on drawing stroke of the subject copying a predetermined single-stroke drawn figure; a detection unit 132 configured to detect a fall count indicating the number of times a drawing acceleration of the subject changes from a positive value to a negative value, based on the drawing stroke information; and an evaluation unit 133 configured to evaluate the motor performance of the subject, based on the fall count.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: January 8, 2019
    Assignee: TOYO UNIVERSITY
    Inventor: Hideo Kawaguchi
  • Publication number: 20160183848
    Abstract: A motor performance evaluation apparatus 100 for evaluating motor performance of a subject, including: an acquisition unit 131 configured to acquire drawing stroke information including position information and time information on drawing stroke of the subject copying a predetermined single-stroke drawn figure; a detection unit 132 configured to detect a fall count indicating the number of times a drawing acceleration of the subject changes from a positive value to a negative value, based on the drawing stroke information; and an evaluation unit 133 configured to evaluate the motor performance of the subject, based on the fall count.
    Type: Application
    Filed: December 28, 2015
    Publication date: June 30, 2016
    Applicant: TOYO UNIVERSITY
    Inventor: Hideo KAWAGUCHI
  • Publication number: 20120025196
    Abstract: An organic thin film transistor includes an organic semiconductor layer, a source electrode and a drain electrode which are separated from each other and are individually in contact with the organic semiconductor layer, a gate insulating film which is in contact with the organic semiconductor layer between the source and drain electrodes, and a gate electrode which is opposed to the organic semiconductor layer and is in contact with the gate insulating film. In the organic thin film transistor, a high-concentration region of the organic semiconductor layer which is located near the source electrode has an impurity concentration set higher than an impurity concentration of a low-concentration region of the organic semiconductor layer, the low-concentration region being located near the gate electrode in the thickness direction of the organic semiconductor layer between the source and drain electrodes.
    Type: Application
    Filed: January 18, 2010
    Publication date: February 2, 2012
    Applicant: TOYO UNIVERSITY
    Inventors: Yasuo Wada, Toru Toyabe, Ken Tsutsui
  • Patent number: 8038849
    Abstract: A process for producing a carbon-particle structure, including the step of irradiating opaque carbon dioxide at and/or near its critical point, as light is scattered, with a UV-wavelength laser beam to produce a carbon-particle structure.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: October 18, 2011
    Assignee: Toyo University Educational Foundation
    Inventors: Toru Maekawa, Yoshikazu Yoshida, Takahiro Fukuda
  • Publication number: 20100292950
    Abstract: With proposed radiation thermometry and radiation thermometry system (10), a thin-film (2) is disposed on a substrate to make a thin-film substrate, and measurement is conducted for polarized radiance components emitted from the thin-film (2) in a direction which is within an angle range ? eic, from a planar normal line of the thin-film (2), where radiance components remain invariable. A temperature of the thin-film (2) is determined on the basis of the measured results of the polarized radiance components. The polarized radiance components are measured using a radiometer (4) by measuring p-wave polarized radiance components which are parallel to an emitting surface including a direction where the polarized radiance components are measured. A pseudo-blackbody (5) is disposed in a mirror symmetrical state to the radiometer (4), and absorbs and negates background radiations to the radiometer (4).
    Type: Application
    Filed: December 11, 2008
    Publication date: November 18, 2010
    Applicant: TOYO UNIVERSITY
    Inventors: Tohru Iuchi, Kensuke Hiraka
  • Patent number: 7807025
    Abstract: A method for realizing carbon dioxide reduction, which is a task to be urgently accomplished from the viewpoint of global environmental problems, is provided. The method includes the steps of irradiating carbon dioxide in a supercritical or subcritical state (i.e., near the critical point) with a UV-wavelength laser beam to decompose carbon dioxide and form a carbon-particle structure.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: October 5, 2010
    Assignee: Toyo University Educational Foundation
    Inventors: Toru Maekawa, Yoshikazu Yoshida, Takahiro Fukuda
  • Publication number: 20100243426
    Abstract: There is provided a method for decomposing a carbon-containing compound including: changing the condition of the carbon-containing compound into a subcritical fluid, a critical fluid or a supercritical fluid state; irradiating the carbon-containing compound with light to decompose, wherein the carbon-containing compound is an organic compound. According to an aspect of the present invention, a carbon nano/microstructure such as a nano/microparticle is obtained at a temperature lower than those used conventionally.
    Type: Application
    Filed: August 25, 2008
    Publication date: September 30, 2010
    Applicant: TOYO UNIVERSITY
    Inventors: Toru Maekawa, Takahiro Fukuda, Nami Fukuda, Takashi Hasumura, Koji Ishii, Nyrki Rantonen, Yoshikata Nakajima, Tatsuro Hanajiri
  • Publication number: 20090223807
    Abstract: A process for producing a carbon-particle structure, including the step of irradiating opaque carbon dioxide at and/or near its critical point, as light is scattered, with a UV-wavelength laser beam to produce a carbon-particle structure.
    Type: Application
    Filed: May 12, 2009
    Publication date: September 10, 2009
    Applicant: Toyo University Educational Foundation
    Inventors: Toru MAEKAWA, Yoshikazu Yoshida, Takahiro Fukuda
  • Publication number: 20080210542
    Abstract: A novel technical method, which can realize carbon dioxide reduction, which is a task to be urgently accomplished from the viewpoint of global environmental problems, can realize carbon dioxide decomposition for the carbon dioxide reduction, and can realize the utilization of carbon resources obtained from the carbon dioxide with a higher added value, is provided by irradiating carbon dioxide in a supercritical or subcritical state with a UV-wavelength laser beam to decompose carbon dioxide and form a carbon-particle structure.
    Type: Application
    Filed: May 25, 2005
    Publication date: September 4, 2008
    Applicant: TOYO UNIVERSITY EDUCATIONAL FOUNDATION
    Inventors: Toru Maekawa, Yoshikazu Yoshida, Takahiro Fukuda