Abstract: Analytical chemical reagents termed non-signal imidazoles and a method for their use that provide a host of advantages for analysis of phosphomonoesters are described. The method and compounds of the invention provide a host of advantages for the analysis of phosphomonoester-containing compounds, namely characteristic, multi-analyte detection with high sensitivity and specificity of known and unknown phosphomonoester-compounds simultaneously.
Type:
Grant
Filed:
June 21, 2006
Date of Patent:
August 23, 2011
Assignee:
Trace Bio Analytics, LLC
Inventors:
Poguang Wang, Guodong Li, Roger W. Giese