Abstract: Injectable compositions for treating affected tissues are prepared by formulating sodium hydrogen sulfite with all other components except tannic acid to yield a first mixture and adding tannic acid to the first mixture, or, by formulating a water-soluble aluminum compound and a chelating agent to yield a first formulation, formulating tannic acid and sodium hydrogen sulfite to yield a second formulation and admixing the first formulation with the second formulation to yield a second mixture and, as needed, adding a polyvalent alcohol and/or a saccharide to the first and/or second formulations or to the first or second mixture, thereby formulating the injectable composition having a pH range of from pH 1.0 to pH 3.5. This preparation can prevent the oxidation of tannic acid and the direct reaction with aluminum ions derived from sodium hydrogen sulfite, whereby the composition can provide a stable formulation as well as ensure effectiveness as an injectable preparation in a solution form.
Type:
Grant
Filed:
May 28, 1996
Date of Patent:
May 12, 1998
Assignee:
Traditional Chinese Medicine Research Laboratory, Inc.
Abstract: The hardening agent contains a composition comprised of tannic acid and potassium aluminium sulfate in a ratio of tannic acid to potassium aluminium sulfate ranging from 10 to 1 to 1 to 50 and a stabilizing agent extracted from crude drugs of plants containing a phenol, flavon, flavonoid, catechin or a polycarboxylic acid.
Type:
Grant
Filed:
July 7, 1993
Date of Patent:
November 28, 1995
Assignee:
Traditional Chinese Medicine Research Laboratory, Inc.
Abstract: The hardening agent contains a composition comprised of tannic acid and potassium aluminum sulfate in a ratio of tannic acid to potassium aluminum sulfate ranging from 10 to 1 to 1 to 50 and a stabilizing agent extracted from crude drugs of plants containing a phenol, flavon, flavonoid, catechin or a polycarboxylic acid.
Type:
Grant
Filed:
April 24, 1991
Date of Patent:
October 12, 1993
Assignee:
Traditional Chinese Medicine Research Laboratory, Inc.