Abstract: Method for selecting mammalian cells having a genetically-desirable trait, the method comprising culturing an embryo in vitro, dividing the cells from the embryo into aliquots, subjecting the cells from at least one of the aliquots to a genetic analysis, and, based on the results of such analysis, selecting an aliquot of cells. Method for selecting mammalian cells having a genetically-desirable trait, the method comprising culturing an embryo in vitro, transferring the cultured embryo into a recipient female, collecting the embryo, dividing the cells from the embryo into aliquots, subjecting the cells from at least one of the aliquots to a genetic analysis, and, based on the results of such analysis, selecting an aliquot of cells.
Type:
Grant
Filed:
January 15, 2021
Date of Patent:
July 1, 2025
Assignee:
TRANS OVA GENETICS, L.C.
Inventors:
Poothappillai K. Kasinathan, Hong Wei, Mark F. Allan, David C. Faber
Abstract: Method for selecting mammalian cells having a genetically-desirable trait, the method comprising culturing an embryo in vitro, dividing the cells from the embryo into aliquots, subjecting the cells from at least one of the aliquots to a genetic analysis, and, based on the results of such analysis, selecting an aliquot of cells. Method for selecting mammalian cells having a genetically-desirable trait, the method comprising culturing an embryo in vitro, transferring the cultured embryo into a recipient female, collecting the embryo, dividing the cells from the embryo into aliquots, subjecting the cells from at least one of the aliquots to a genetic analysis, and, based on the results of such analysis, selecting an aliquot of cells.
Type:
Application
Filed:
January 15, 2021
Publication date:
June 24, 2021
Applicant:
TRANS OVA GENETICS, L.C.
Inventors:
Poothappillai K. Kasinathan, Hong Wei, Mark F. Allan, David C. Faber
Abstract: Genetic tests, such as whole genome analysis (WGA), have been employed to identify genetically superior embryos. The disclosed methods extend in vitro culture time of embryos while awaiting results of genetic tests being performed on a portion of the same embryos. The disclosed methods also help expand the number of cells in each embryo before implantation in the recipient.
Type:
Grant
Filed:
October 18, 2013
Date of Patent:
February 23, 2021
Assignee:
TRANS OVA GENETICS, L.C.
Inventors:
Poothappillai K. Kasinathan, Hong Wei, Mark F. Allan, David C. Faber