Patents Assigned to TransAlgae (Israel) Ltd.
  • Patent number: 11939576
    Abstract: The present invention provides non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.
    Type: Grant
    Filed: August 26, 2020
    Date of Patent: March 26, 2024
    Assignee: TRANSALGAE ISRAEL LTD.
    Inventor: Ofra Chen
  • Patent number: 11344590
    Abstract: Transgenic microalgae expressing at least one exogenous biologically active protein. The protein-expressing microalgae are used for the oral delivery of the biologically active protein to the target organism in its intact and functional form. The exogenous protein, expressed in algae, is characterized by being biologically active, exerting at least one specific activity having a beneficial effect on the subject consuming the algae. The transgenic microalgae are used as animal food for aquatic or land animals welfare or as food supplement for human healthcare.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: May 31, 2022
    Assignee: TRANSALGAE ISRAEL LTD.
    Inventors: Shiri Moshitzky, Doron Eisenstadt, Guy Levi, Ofra Chen
  • Publication number: 20210032625
    Abstract: The present invention provides non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.
    Type: Application
    Filed: August 26, 2020
    Publication date: February 4, 2021
    Applicant: TRANSALGAE ISRAEL LTD.
    Inventor: Ofra CHEN
  • Patent number: 10781447
    Abstract: Provided are non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: September 22, 2020
    Assignee: TRANSALGAE ISRAEL LTD.
    Inventor: Ofra Chen
  • Publication number: 20200063152
    Abstract: The present invention provides edible vaccines comprising transgenic microalgae expressing at least one exogenous antigen or an intervening organism comprising the transgenic microalgae. The antigen expressing microalgae are used for oral delivery of the antigen to a target organism in its intact and functional form. The exogenous antigen, expressed in the microalgae, is characterized by exerting at least one immunogenic response in the subject consuming the vaccine.
    Type: Application
    Filed: October 11, 2019
    Publication date: February 27, 2020
    Applicant: TRANSALGAE ISRAEL LTD.
    Inventor: Ofra CHEN
  • Patent number: 10480002
    Abstract: Provided are edible vaccines including transgenic microalgae expressing at least one exogenous antigen or an intervening organism including the transgenic microalgae. The antigen expressing microalgae are used for oral delivery of the antigen to a target organism in its intact and functional form. The exogenous antigen, expressed in the microalgae, is characterized by exerting at least one immunogenic response in the subject consuming the vaccine.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: November 19, 2019
    Assignee: TRANSALGAE ISRAEL LTD.
    Inventor: Ofra Chen
  • Publication number: 20180195065
    Abstract: Provided are non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.
    Type: Application
    Filed: July 14, 2016
    Publication date: July 12, 2018
    Applicant: TRANSALGAE ISRAEL LTD.
    Inventor: Ofra CHEN
  • Publication number: 20180036357
    Abstract: Transgenic microalgae expressing at least one exogenous biologically active protein. The protein-expressing microalgae are used for the oral delivery of the biologically active protein to the target organism in its intact and functional form. The exogenous protein, expressed in algae, is characterized by being biologically active, exerting at least one specific activity having a beneficial effect on the subject consuming the algae. The transgenic microalgae are used as animal food for aquatic or land animals welfare or as food supplement for human healthcare.
    Type: Application
    Filed: October 24, 2017
    Publication date: February 8, 2018
    Applicant: TRANSALGAE ISRAEL LTD.
    Inventors: Shiri MOSHITZKY, Doron EISENSTADT, Guy LEVI, Ofra CHEN
  • Patent number: 9827280
    Abstract: Transgenic microalgae expressing at least one exogenous biologically active protein. The protein-expressing microalgae are used for the oral delivery of the biologically active protein to the target organism in its intact and functional form. The exogenous protein, expressed in algae, is characterized by being biologically active, exerting at least one specific activity having a beneficial effect on the subject consuming the algae. The transgenic microalgae are used as animal food for aquatic or land animals welfare or as food supplement for human healthcare.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: November 28, 2017
    Assignee: TRANSALGAE ISRAEL LTD.
    Inventors: Shiri Moshitzky, Doron Eisenstadt, Guy Levi, Ofra Chen
  • Publication number: 20160346373
    Abstract: Provided are edible vaccines including transgenic microalgae expressing at least one exogenous antigen or an intervening organism including the transgenic microalgae. The antigen expressing microalgae are used for oral delivery of the antigen to a target organism in its intact and functional form. The exogenous antigen, expressed in the microalgae, is characterized by exerting at least one immunogenic response in the subject consuming the vaccine.
    Type: Application
    Filed: February 12, 2015
    Publication date: December 1, 2016
    Applicant: TRANSALGAE ISRAEL LTD.
    Inventor: Ofra CHEN
  • Publication number: 20110045593
    Abstract: Genetic mechanisms for mitigating the effects of introgression of a genetically engineered genetic trait of cultivated algae or cyanobacteria to its wild type or to an undesirable, interbreeding related species, as well as preventing the establishment of the transgenic algae or cyanobacteria in natural ecosystems by suppressing the activity of the carbon concentrating mechanism.
    Type: Application
    Filed: August 17, 2010
    Publication date: February 24, 2011
    Applicant: TransAlgae (Israel) Ltd.
    Inventors: Ofra Chen, Shai Ufaz, Doron Eisenstadt, Daniella Schatz, Jonathan Gressel, Shai Einbinder