Patents Assigned to TransAlgae (Israel) Ltd.
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Patent number: 11939576Abstract: The present invention provides non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.Type: GrantFiled: August 26, 2020Date of Patent: March 26, 2024Assignee: TRANSALGAE ISRAEL LTD.Inventor: Ofra Chen
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Patent number: 11344590Abstract: Transgenic microalgae expressing at least one exogenous biologically active protein. The protein-expressing microalgae are used for the oral delivery of the biologically active protein to the target organism in its intact and functional form. The exogenous protein, expressed in algae, is characterized by being biologically active, exerting at least one specific activity having a beneficial effect on the subject consuming the algae. The transgenic microalgae are used as animal food for aquatic or land animals welfare or as food supplement for human healthcare.Type: GrantFiled: October 24, 2017Date of Patent: May 31, 2022Assignee: TRANSALGAE ISRAEL LTD.Inventors: Shiri Moshitzky, Doron Eisenstadt, Guy Levi, Ofra Chen
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Publication number: 20210032625Abstract: The present invention provides non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.Type: ApplicationFiled: August 26, 2020Publication date: February 4, 2021Applicant: TRANSALGAE ISRAEL LTD.Inventor: Ofra CHEN
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Patent number: 10781447Abstract: Provided are non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.Type: GrantFiled: July 14, 2016Date of Patent: September 22, 2020Assignee: TRANSALGAE ISRAEL LTD.Inventor: Ofra Chen
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Publication number: 20200063152Abstract: The present invention provides edible vaccines comprising transgenic microalgae expressing at least one exogenous antigen or an intervening organism comprising the transgenic microalgae. The antigen expressing microalgae are used for oral delivery of the antigen to a target organism in its intact and functional form. The exogenous antigen, expressed in the microalgae, is characterized by exerting at least one immunogenic response in the subject consuming the vaccine.Type: ApplicationFiled: October 11, 2019Publication date: February 27, 2020Applicant: TRANSALGAE ISRAEL LTD.Inventor: Ofra CHEN
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Patent number: 10480002Abstract: Provided are edible vaccines including transgenic microalgae expressing at least one exogenous antigen or an intervening organism including the transgenic microalgae. The antigen expressing microalgae are used for oral delivery of the antigen to a target organism in its intact and functional form. The exogenous antigen, expressed in the microalgae, is characterized by exerting at least one immunogenic response in the subject consuming the vaccine.Type: GrantFiled: February 12, 2015Date of Patent: November 19, 2019Assignee: TRANSALGAE ISRAEL LTD.Inventor: Ofra Chen
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Publication number: 20180195065Abstract: Provided are non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.Type: ApplicationFiled: July 14, 2016Publication date: July 12, 2018Applicant: TRANSALGAE ISRAEL LTD.Inventor: Ofra CHEN
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Publication number: 20180036357Abstract: Transgenic microalgae expressing at least one exogenous biologically active protein. The protein-expressing microalgae are used for the oral delivery of the biologically active protein to the target organism in its intact and functional form. The exogenous protein, expressed in algae, is characterized by being biologically active, exerting at least one specific activity having a beneficial effect on the subject consuming the algae. The transgenic microalgae are used as animal food for aquatic or land animals welfare or as food supplement for human healthcare.Type: ApplicationFiled: October 24, 2017Publication date: February 8, 2018Applicant: TRANSALGAE ISRAEL LTD.Inventors: Shiri MOSHITZKY, Doron EISENSTADT, Guy LEVI, Ofra CHEN
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Patent number: 9827280Abstract: Transgenic microalgae expressing at least one exogenous biologically active protein. The protein-expressing microalgae are used for the oral delivery of the biologically active protein to the target organism in its intact and functional form. The exogenous protein, expressed in algae, is characterized by being biologically active, exerting at least one specific activity having a beneficial effect on the subject consuming the algae. The transgenic microalgae are used as animal food for aquatic or land animals welfare or as food supplement for human healthcare.Type: GrantFiled: February 23, 2015Date of Patent: November 28, 2017Assignee: TRANSALGAE ISRAEL LTD.Inventors: Shiri Moshitzky, Doron Eisenstadt, Guy Levi, Ofra Chen
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Publication number: 20160346373Abstract: Provided are edible vaccines including transgenic microalgae expressing at least one exogenous antigen or an intervening organism including the transgenic microalgae. The antigen expressing microalgae are used for oral delivery of the antigen to a target organism in its intact and functional form. The exogenous antigen, expressed in the microalgae, is characterized by exerting at least one immunogenic response in the subject consuming the vaccine.Type: ApplicationFiled: February 12, 2015Publication date: December 1, 2016Applicant: TRANSALGAE ISRAEL LTD.Inventor: Ofra CHEN
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Publication number: 20110045593Abstract: Genetic mechanisms for mitigating the effects of introgression of a genetically engineered genetic trait of cultivated algae or cyanobacteria to its wild type or to an undesirable, interbreeding related species, as well as preventing the establishment of the transgenic algae or cyanobacteria in natural ecosystems by suppressing the activity of the carbon concentrating mechanism.Type: ApplicationFiled: August 17, 2010Publication date: February 24, 2011Applicant: TransAlgae (Israel) Ltd.Inventors: Ofra Chen, Shai Ufaz, Doron Eisenstadt, Daniella Schatz, Jonathan Gressel, Shai Einbinder