Patents Assigned to TransBio Ltd.
  • Fn14 Binding Proteins and Uses Thereof
    Publication number: 20150218278
    Abstract: The present disclosure provides proteins comprising antibody antigen binding domains that bind to Fn14 and uses thereof. The present disclosure also provides methods for treating wasting disorders, such as cachexia.
    Type: Application
    Filed: October 31, 2014
    Publication date: August 6, 2015
    Applicant: TransBio Ltd
    Inventors: Nicholas Johannes Hoogenraad, Amelia Jane Johnston, John Silke
  • FN14 binding proteins and uses thereof
    Patent number: 9006397
    Abstract: The present disclosure provides proteins comprising antibody antigen binding domains that bind to Fn14 and uses thereof. The present disclosure also provides methods for treating wasting disorders, such as cachexia.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: April 14, 2015
    Assignee: TransBio Ltd
    Inventors: Nicholas Johannes Hoogenraad, Amelia Jane Johnston, John Silke
  • Fn14 Binding Proteins and Uses Thereof
    Publication number: 20130273036
    Abstract: The present disclosure provides proteins comprising antibody antigen binding domains that bind to Fn14 and uses thereof. The present disclosure also provides methods for treating wasting disorders, such as cachexia.
    Type: Application
    Filed: March 27, 2013
    Publication date: October 17, 2013
    Applicant: TransBio Ltd
    Inventors: Nicholas Johannes Hoogenraad, Amelia Jane Johnston, John Silke
  • Markers of Endothelial Progenitor Cells and Uses Thereof
    Publication number: 20130224116
    Abstract: The present invention provides markers of endothelial progenitor cells (EPCs) and use of those markers and reagents that bind thereto to detect EPC cells or diagnose, prognose, treat or prevent EPC-associated conditions.
    Type: Application
    Filed: November 7, 2011
    Publication date: August 29, 2013
    Applicant: TransBio Ltd.
    Inventors: Claudine Sharon Bonder, Angel Fransciso Lopez, Gert Hoy Talbo
  • PROTEINS THAT BIND PI16 AND USES THEREOF
    Publication number: 20130171153
    Abstract: The present disclosure provides an isolated protein comprising at least one antibody variable region that is capable of binding to peptidase inhibitor 16 (PI16), wherein the protein is also capable of competitively inhibiting binding of an antibody produced by a hybridoma designated CRCBT-02-001 deposited with the ATCC under Accession Number PTA-10685 to PI16. The present invention also provides use of the protein, e.g., in diagnosis, therapy or to isolate cells, preferably Treg cells.
    Type: Application
    Filed: April 18, 2011
    Publication date: July 4, 2013
    Applicant: TransBio Ltd.
    Inventors: Simon Barry, Doreen Krumbiegel, Nicola Ga-Ling Eastaff-Leung, Ian Cameron Nicholson, Heddy Zola