Patents Assigned to Transkaryotic Therapies Inc., a Massachusetts corporation
  • Nucleic acid encoding a chimeric polypeptide
    Publication number: 20030152560
    Abstract: A therepeutic method whereby an individual suspected of having an &agr;-galactosidase A deficiency, such as Fabry disease, is treated either with (1) human cells that have been genetically modified to overexpress and secrete human &agr;-gal A, or (2) purified human &agr;-gal A obtained from cultured, genetically modified human cells.
    Type: Application
    Filed: December 12, 2002
    Publication date: August 14, 2003
    Applicant: Transkaryotic Therapies Inc., a Massachusetts corporation
    Inventors: Richard F. Selden, Marianne Borowski, Frances P. Gillispie, Carol M. Kinoshita, Douglas A. Treco, Melanie D. Williams