Abstract: The present invention provides an apparatus and method for creating hemostasis at a subcutaneous vascular puncture. The method and apparatus is intended, but not limited to, vascular punctures following trans-radial arterial procedures, e.g. catheterization and percutaneous coronary intervention.

Abstract: The present invention relates a closure device implant for sealing an opening formed through biological tissue including a plug, a rigid wire including a plastically deformable portion configurable between an unrestrained position and a restrained position relative to the plug, wherein a distal end of the wire is substantially spherically shaped, and a footplate attached to the wire, wherein the footplate comprises an elongated plate portion including a wire channel. The present invention also relates to a closure device deployment device including an elongated housing, a sheath assembly connected to the housing, and at least two sliding members slidably connected to the housing.

Abstract: The present invention relates generally to specially designed magnesium-aluminum (“Mg—Al”) alloys and medical uses thereof in a hemodynamic environment, and, more particularly to devices for sealing an opening formed through biological tissue (such as blood vessels) made from such specially designed magnesium-aluminum alloys.

Abstract: The present invention relates generally to medical devices and methods for sealing and closing passages formed through tissue. More specifically, the present invention relates to devices for sealing or closing an opening formed through biological tissue comprising a distal or outside margin or surface, and a proximal or inside margin or surface (i.e., a wall thickness), and to apparatuses and methods for delivering such devices, to control (or prevent or stop) bleeding (or the flow of other biological fluid or tissue). The openings comprise percutaneously formed punctures, incisions, or other openings formed through biological tissue, such as in blood vessels, organs, and the like.