Patents Assigned to Transonic Systems, Inc.
  • Publication number: 20080033314
    Abstract: A method for determining cardiac output in conjunction with flow through an extracorporeal circuit, wherein flow through an arterial line of the extracorporeal circuit is temporarily reversed and an indicator is passed through the cardiopulmonary circuit. A dilution curve is measured in the arterial line of the extracorporeal circuit during the reversed flow, and cardiac output is determined corresponding to the measured dilution curve.
    Type: Application
    Filed: July 23, 2007
    Publication date: February 7, 2008
    Applicant: Transonic Systems, Inc.
    Inventor: Nikolai Krivitski
  • Patent number: 7297280
    Abstract: The measurement of blood flow in a dialysis shunt is obtained by injection of an indicator material into a venous line leading from dialysis equipment to the shunt. The blood flow in an arterial line leading from the shunt at a location downstream of the venous line to the dialysis equipment is monitored by an arterial line sensor for the presence of the indicator material. A detector connected to the sensor provides a dilution curve in response to the presence of the indicator material and the blood flow in the shunt is calculated from the area under the dilution curve. The locations of the arterial and venous lines in the shunt can be reversed to obtain a measurement of blood recirculation from the venous line into the arterial line.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: November 20, 2007
    Assignee: Transonic Systems, Inc.
    Inventors: Nikolai M. Krivitski, David R. MacGibbon
  • Patent number: 7275447
    Abstract: A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: October 2, 2007
    Assignee: Transonic Systems, Inc.
    Inventors: Nikolai M. Krivitski, Cornelis J. Drost
  • Patent number: 7261696
    Abstract: A method and apparatus for determining cardiac output in conjunction with flow through an extracorporeal circuit, wherein flow through an arterial line of the extracorporeal circuit is temporarily reversed and an indicator is passed through the cardiopulmonary circuit. A dilution curve is measured in the arterial line of the extracorporeal circuit during the reversed flow, and cardiac output is determined corresponding to the measured dilution curve.
    Type: Grant
    Filed: September 9, 2004
    Date of Patent: August 28, 2007
    Assignee: Transonic Systems, Inc.
    Inventor: Nikolai M. Krivitski
  • Publication number: 20070137296
    Abstract: A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.
    Type: Application
    Filed: February 13, 2007
    Publication date: June 21, 2007
    Applicant: Transonic Systems, Inc.
    Inventors: Nikolai Krivitski, Cornelis Drost
  • Patent number: 7210359
    Abstract: A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: May 1, 2007
    Assignee: Transonic Systems, Inc.
    Inventors: Nikolai M. Krivitski, Cornelis J. Drost
  • Patent number: 7194919
    Abstract: A transit time ultrasound sensor is employed for the measurement of liquid flow in a conduit, the sensor having an acoustic path formed of materials matched in ultrasound properties to the flow under test, and designed to conform to the shape of the conduit. The sensor can be configured as a clamp on device, wherein the conduit walls are constructed from such an ultrasonically-matched material. Alternately, in a perivascular configuration, the ultrasonically-matched material is operably intermediate the blood vessel and the sensor.
    Type: Grant
    Filed: May 29, 2003
    Date of Patent: March 27, 2007
    Assignee: Transonic Systems, Inc.
    Inventors: Yuri Shkarlet, Cornelis J. Drost
  • Publication number: 20060243061
    Abstract: A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.
    Type: Application
    Filed: July 11, 2006
    Publication date: November 2, 2006
    Applicant: Transonic Systems, Inc.
    Inventors: Nikolai Krivitski, Cornelis Drost
  • Patent number: 7121150
    Abstract: A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: October 17, 2006
    Assignee: Transonic Systems, Inc.
    Inventors: Nikolai M. Krivitski, Cornelis J. Drost
  • Patent number: 7112176
    Abstract: A catheter for retrograde orientation in a blood flow is used to determine the blood flow rate by thermodilution measurements. The determination of the blood flow rate accommodates injectate induced thermal influences on a dilution thermal sensor, wherein the thermal influences can occur prior to introduction of the injectate into the blood flow.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: September 26, 2006
    Assignee: Transonic Systems, Inc.
    Inventors: Nikolai M. Krivitski, Victor V. Kislukhin
  • Publication number: 20060129053
    Abstract: A catheter for retrograde orientation in a blood flow is used to determine the blood flow rate by thermodilution measurements. The determination of the blood flow rate accommodates injectate induced thermal influences on a dilution thermal sensor, wherein the thermal influences can occur prior to introduction of the injectate into the blood flow.
    Type: Application
    Filed: January 9, 2006
    Publication date: June 15, 2006
    Applicant: Transonic Systems, Inc.
    Inventors: Nikolai Krivitski, Victor Kislukhin
  • Publication number: 20060052963
    Abstract: A sensor probe provides a pair of unique signal paths through a test material, wherein one configuration of the probe provides identical external portions of the signal paths such that a selected parameter of a measuring signal passing along at least two of the unique signal paths is measured. From these measurements, a method is provided for calculating at least one parameter of the test material, wherein the parameter can include an intrinsic parameter as well as a condition of state.
    Type: Application
    Filed: September 7, 2004
    Publication date: March 9, 2006
    Applicant: Transonic Systems, Inc.
    Inventor: Yuri Shkarlet
  • Publication number: 20060052715
    Abstract: A method and apparatus for determining cardiac output in conjunction with flow through an extracorporeal circuit, wherein flow through an arterial line of the extracorporeal circuit is temporarily reversed and an indicator is passed through the cardiopulmonary circuit. A dilution curve is measured in the arterial line of the extracorporeal circuit during the reversed flow, and cardiac output is determined corresponding to the measured dilution curve.
    Type: Application
    Filed: September 9, 2004
    Publication date: March 9, 2006
    Applicant: Transonic Systems, Inc.
    Inventor: Nikolai Krivitski
  • Patent number: 6986744
    Abstract: A method and apparatus for determining an angioplasty induced blood flow changes, wherein the apparatus includes the catheter having a port for introducing a blood property change in a downstream sensor. The downstream sensor and the catheter are configured to space the sensor from an adjacent vessel wall so as to minimize effects of the vessel wall during sensing of the blood property change.
    Type: Grant
    Filed: February 2, 1999
    Date of Patent: January 17, 2006
    Assignee: Transonic Systems, Inc.
    Inventor: Nikolai M. Krivitski
  • Publication number: 20050178732
    Abstract: The measurement of blood flow in a dialysis shunt is obtained by injection of an indicator material into a venous line leading from dialysis equipment to the shunt. The blood flow in an arterial line leading from the shunt at a location downstream of the venous line to the dialysis equipment is monitored by an arterial line sensor for the presence of the indicator material. A detector connected to the sensor provides a dilution curve in response to the presence of the indicator material and the blood flow in the shunt is calculated from the area under the dilution curve. The locations of the arterial and venous lines in the shunt can be reversed to obtain a measurement of blood recirculation from the venous line into the arterial line.
    Type: Application
    Filed: April 13, 2005
    Publication date: August 18, 2005
    Applicant: Transonic Systems, Inc.
    Inventors: Nikolai Krivitski, David MacGibbon
  • Patent number: 6926838
    Abstract: The measurement of blood flow in a dialysis shunt is obtained by injection of an indicator material into a venous line leading from dialysis equipment to the shunt. The blood flow in an arterial line leading from the shunt at a location downstream of the venous line to the dialysis equipment is monitored by an arterial line sensor for the presence of the indicator material. A detector connected to the sensor provides a dilution curve in response to the presence of the indicator material and the blood flow in the shunt is calculated from the area under the dilution curve. The locations of the arterial and venous lines in the shunt can be reversed to obtain a measurement of blood recirculation from the venous line into the arterial line.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: August 9, 2005
    Assignee: Transonic Systems, Inc.
    Inventors: Nikolai M. Krivitski, David R. MacGibbon
  • Publication number: 20050166683
    Abstract: A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.
    Type: Application
    Filed: March 18, 2005
    Publication date: August 4, 2005
    Applicant: Transonic Systems, Inc.
    Inventors: Nikolai Krivitski, Cornelis Drost
  • Publication number: 20050171446
    Abstract: A method and apparatus for determining an angioplasty induced blood flow changes, wherein the apparatus includes the catheter having a port for introducing a blood property change in a downstream sensor. The downstream sensor and the catheter are configured to space the sensor from an adjacent vessel wall so as to minimize effects of the vessel wall during sensing of the blood property change.
    Type: Application
    Filed: March 25, 2005
    Publication date: August 4, 2005
    Applicant: Transonic Systems, Inc
    Inventor: Nikolai Krivitski
  • Patent number: 6868739
    Abstract: A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: March 22, 2005
    Assignee: Transonic Systems, Inc.
    Inventors: Nikolai M. Krivitski, Cornelis J. Drost
  • Publication number: 20050051496
    Abstract: The measurement of blood flow in a dialysis shunt is obtained by injection of an indicator material into a venous line leading from dialysis equipment to the shunt. The blood flow in an arterial line leading from the shunt at a location downstream of the venous line to the dialysis equipment is monitored by an arterial line sensor for the presence of the indicator material. A detector connected to the sensor provides a dilution curve in response to the presence of the indicator material and the blood flow in the shunt is calculated from the area under the dilution curve. The locations of the arterial and venous lines in the shunt can be reversed to obtain a measurement of blood recirculation from the venous line into the arterial line.
    Type: Application
    Filed: June 18, 2004
    Publication date: March 10, 2005
    Applicant: Transonic Systems, Inc.
    Inventors: Nikolai Krivitski, David MacGibbon