Abstract: The present invention provides methods for inducing and expanding anti-tumor immunity leading to enhanced clinical and immunotherapeutic responses. The invention also provides novel compositions and methods for the treatment of cancer.
Abstract: The invention relates to compositions and methods for treating a host infected with a pathogen. The composition comprising a population of polyclonal bispecific binding molecules that can target and eliminate a host cell infected with the pathogen. Methods for activating and arming cytotoxic immune cells with the composition for use in treating a patient infected with a pathogen are also provided.
Type:
Grant
Filed:
March 3, 2015
Date of Patent:
November 22, 2016
Assignees:
TRANSTARGET, INC., WAYNE STATE UNIVERSITY
Abstract: The present invention provides compositions and methods for targeting an extracellular matrix derived (EMD) peptide predominantly to an injured tissue, as opposed to an uninjured tissue in vivo. The targeted EMD peptide facilitates the repair and/or regeneration of the injured tissue by providing a surface for cells to attach and grow, thereby facilitating the repair and/or regeneration of the injured tissue.
Type:
Grant
Filed:
May 30, 2008
Date of Patent:
November 18, 2014
Assignees:
TransTarget, Inc., The Regents of the University of California
Inventors:
Randall J. Lee, Shirley Mihardja, Manley Huang, James W. Larrick
Abstract: This invention provides compositions of matter, articles of manufacture and methods for delivering and/or affixing a stem cell to a target tissue. This invention also provides related nucleic acids, vectors, cell, methods of production, and kits.
Type:
Grant
Filed:
April 23, 2003
Date of Patent:
August 18, 2009
Assignees:
Roger Williams Hospital, TransTarget, Inc.
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