Patents Assigned to Travera, Inc.
  • Assessing immune system function and status
    Patent number: 12754123
    Abstract: The invention provides methods for assessing immune system function and status based on cellular analysis. Methods of the present invention involve obtaining mass properties of immune cells collected in a tissue or body fluid sample from a subject. Such mass properties may include the mass of one or more immune cells and/or changes in mass of such immune cells over a period of time. Such data is then used for determining a status of the subject's immune response, and subsequent diagnosis and treatment of an infection or immunological disease or dysfunction.
    Type: Grant
    Filed: October 31, 2022
    Date of Patent: October 6, 2026
    Assignee: Travera, Inc.
    Inventors: Robert Kimmerling, Selim Olcum, Mark Stevens, Anthony Minnah, Madeleine Vacha
  • Identifying cancer therapies
    Patent number: 12362038
    Abstract: In silico tools are used to determine possibly effective therapies for treating a patient's cancer based on patient, drug, and cancer information. Functional assays can be performed on living cancer cells from the patient to evaluate the possibly effective therapies along with subsequent genomic or other more destructive assays to provide additional information from a single sample. Drug, patient, cancer, and outcome information can be recorded and updated iteratively and analyzed using machine learning to identify correlations between various patient, cancer, and drug characteristics and expected outcomes and drug efficacies.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: July 15, 2025
    Assignee: Travera, Inc.
    Inventors: Rob Kimmerling, Selim Olcum, Clifford Reid, Mark Stevens
  • Cellular measurement, calibration, and classification
    Patent number: 12345622
    Abstract: The invention provides devices and methods for linked multimodal measurements of individual particles using a mass sensor and an additional sensor.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: July 1, 2025
    Assignee: Travera, Inc.
    Inventors: Robert Kimmerling, Selim Olcum, Mark Stevens
  • Treatment response assessment using normalized single cell measurements
    Patent number: 12105081
    Abstract: The present invention includes methods and systems for assessing a cellular response to a treatment modality, such as potential drug candidate, by comparing normalized single-cell measurements of cellular properties without the need of a calibration step.
    Type: Grant
    Filed: April 26, 2022
    Date of Patent: October 1, 2024
    Assignee: Travera, Inc.
    Inventors: Robert Kimmerling, Selim Olcum, Mark Stevens
  • Cellular measurement, calibration, and classification
    Patent number: 11530974
    Abstract: The invention provides devices and methods for linked multimodal measurements of individual particles using a mass sensor and an additional sensor.
    Type: Grant
    Filed: April 26, 2022
    Date of Patent: December 20, 2022
    Assignee: Travera, Inc.
    Inventors: Robert Kimmerling, Selim Olcum, Mark Stevens
  • Calibration of a functional biomarker instrument
    Patent number: 11346755
    Abstract: Methods of calibration are provided. A method comprises introducing a material with cell-like properties and a known mass into a sensor on a measurement instrument to generate a calibration reading and adjusting an output module of the measurement instrument until the measurement instrument calibrates to the known mass for the material.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: May 31, 2022
    Assignee: Travera, Inc.
    Inventors: Rob Kimmerling, Anthony Minnah, Selim Olcum, Mark Stevens, Madeleine Vacha