Patents Assigned to Trega Biosciences, Inc.
  • Use of a cytokine regulatory agent to treat rheumatoid arthritis
    Patent number: 5741774
    Abstract: The present invention relates to the use of a cytokine regulatory agent to reduce the severity of rheumatoid arthritis.
    Type: Grant
    Filed: September 27, 1996
    Date of Patent: April 21, 1998
    Assignee: Trega Biosciences, Inc.
    Inventors: Beverly E. Girten, Ronald R. Tuttle
  • Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels
    Patent number: 5726156
    Abstract: The present invention relates to novel peptides that are potent cytokine regulatory agents. In addition, the present invention relates to pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a cytokine regulatory agent. Administration of such a cytokine regulatory agent to a subject can enhance or restrain cytokine activity. Thus, the present invention provides a method of regulating cytokine activity in a subject having a condition characterized by aberrant or altered cytokine activity. The invention also provides methods of treating such conditions, including, for example, disuse deconditioning, diseases mediated by nitric oxide and cytokines, adverse drug reactions, obesity, septic shock, and adverse side effects due to cancer chemotherapy or occurring as in response to organ transplantation.
    Type: Grant
    Filed: September 12, 1995
    Date of Patent: March 10, 1998
    Assignee: Trega Biosciences, Inc.
    Inventors: Beverly E. Girten, Ali Andalibi, Amaresh Basu, Patrick Fagan, Richard A. Houghten, Costas C. Loullis, Paul Omholt, Ronald R. Tuttle, Mark J. Suto, Patricia A. Weber