Patents Assigned to Tremeau Pharmaceuticals, Inc.
  • Purified forms of rofecoxib, methods of manufacture and use
    Patent number: 11872206
    Abstract: The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
    Type: Grant
    Filed: July 1, 2022
    Date of Patent: January 16, 2024
    Assignee: Tremeau Pharmaceuticals, Inc.
    Inventors: Raymond D. Skwierczynski, Bradford C. Sippy, Jean-Marie Schneider, Simon H. Drouin, Charles Guerin
  • Deuterated etoricoxib, methods of manufacture, and use thereof
    Patent number: 11858909
    Abstract: Disclosed herein are compounds, such as compounds of Formulae (I), (II), and (III), and d3-etoricoxib, and pharmaceutically acceptable salts, hydrates, solvates, polymorphs, co-crystals, metabolites, and prodrugs thereof, and compositions, methods, uses, and kits thereof. The compounds disclosed herein are COX inhibitors and are therefore useful for the treatment and/or prevention of various conditions (e.g., inflammation, pain, or fever).
    Type: Grant
    Filed: August 27, 2021
    Date of Patent: January 2, 2024
    Assignee: Tremeau Pharmaceuticals, Inc.
    Inventor: Bradford C. Sippy
  • Purified forms of rofecoxib, methods of manufacture and use
    Patent number: 11617735
    Abstract: The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
    Type: Grant
    Filed: June 28, 2022
    Date of Patent: April 4, 2023
    Assignee: Tremeau Pharmaceuticals, Inc.
    Inventors: Raymond D. Skwierczynski, Bradford C. Sippy, Jean-Marie Schneider, Simon H. Drouin, Charles Guerin
  • Purified forms of rofecoxib, methods of manufacture and use
    Patent number: 11576890
    Abstract: The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: February 14, 2023
    Assignee: Tremeau Pharmaceuticals, Inc.
    Inventors: Raymond D. Skwierczynski, Bradford C. Sippy, Jean-Marie Schneider, Simon H. Drouin, Charles Guerin
  • Purified forms of rofecoxib, methods of manufacture and use
    Patent number: 11559509
    Abstract: The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
    Type: Grant
    Filed: June 28, 2022
    Date of Patent: January 24, 2023
    Assignee: Tremeau Pharmaceuticals, Inc.
    Inventors: Raymond D. Skwierczynski, Bradford C. Sippy, Jean-Marie Schneider, Simon H. Drouin, Charles Guerin
  • PURIFIED FORMS OF ROFECOXIB, METHODS OF MANUFACTURE AND USE
    Publication number: 20220409568
    Abstract: The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
    Type: Application
    Filed: June 28, 2022
    Publication date: December 29, 2022
    Applicant: Tremeau Pharmaceuticals, Inc.
    Inventors: Raymond D. Skwierczynski, Bradford C. Sippy, Jean-Marie Schneider, Simon H. Drouin, Charles Guerin
  • DOSAGE FORMS OF ROFECOXIB AND RELATED METHODS
    Publication number: 20220409575
    Abstract: The subject matter disclosed herein relates to novel doses and dosage forms of rofecoxib having a therapeutic benefit.
    Type: Application
    Filed: June 30, 2022
    Publication date: December 29, 2022
    Applicant: Tremeau Pharmaceuticals, Inc.
    Inventors: Bradford C. Sippy, Raymond D. Skwierczynski, Travis E. Helm
  • PURIFIED FORMS OF ROFECOXIB, METHODS OF MANUFACTURE AND USE
    Publication number: 20220378736
    Abstract: The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
    Type: Application
    Filed: July 1, 2022
    Publication date: December 1, 2022
    Applicant: Tremeau Pharmaceuticals, Inc.
    Inventors: Raymond D. Skwierczynski, Bradford C. Sippy, Jean-Marie Schneider, Simon H. Drouin, Charles Guerin
  • PURIFIED FORMS OF ROFECOXIB, METHODS OF MANUFACTURE AND USE
    Publication number: 20220362206
    Abstract: The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
    Type: Application
    Filed: June 28, 2022
    Publication date: November 17, 2022
    Applicant: Tremeau Pharmaceuticals, Inc.
    Inventors: Raymond D. Skwierczynski, Bradford C. Sippy, Jean-Marie Schneider, Simon H. Drouin, Charles Guerin
  • DEUTERATED ETORICOXIB, METHODS OF MANUFACTURE, AND USE THEREOF
    Publication number: 20220332696
    Abstract: Disclosed herein are compounds, such as compounds of Formulae (I), (II), and (III), and d3-etoricoxib, and pharmaceutically acceptable salts, hydrates, solvates, polymorphs, co-crystals, metabolites, and prodrugs thereof, and compositions, methods, uses, and kits thereof. The compounds disclosed herein are COX inhibitors and are therefore useful for the treatment and/or prevention of various conditions (e.g., inflammation, pain, or fever).
    Type: Application
    Filed: August 27, 2021
    Publication date: October 20, 2022
    Applicant: Tremeau Pharmaceuticals, Inc.
    Inventor: Bradford C. Sippy
  • NOVEL DOSAGE FORMS OF ROFECOXIB AND RELATED METHODS
    Publication number: 20220047542
    Abstract: The subject matter disclosed herein relates to novel doses and dosage forms of rofecoxib having a therapeutic benefit.
    Type: Application
    Filed: October 28, 2021
    Publication date: February 17, 2022
    Applicant: Tremeau Pharmaceuticals, Inc.
    Inventors: Bradford C. Sippy, Raymond D. Skwierczynski, Travis E. Helm
  • Deuterated etoricoxib, methods of manufacture, and use thereof
    Patent number: 11161833
    Abstract: Disclosed herein are compounds, such as compounds of Formulae (I), (II), and (III), and d3-etoricoxib, and pharmaceutically acceptable salts, hydrates, solvates, polymorphs, co-crystals, metabolites, and prodrugs thereof, and compositions, methods, uses, and kits thereof. The compounds disclosed herein are COX inhibitors and are therefore useful for the treatment and/or prevention of various conditions (e.g., inflammation, pain, or fever).
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: November 2, 2021
    Assignee: Tremeau Pharmaceuticals, Inc.
    Inventor: Bradford C. Sippy
  • PURIFIED FORMS OF ROFECOXIB, METHODS OF MANUFACTURE AND USE
    Publication number: 20210236455
    Abstract: The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
    Type: Application
    Filed: February 26, 2021
    Publication date: August 5, 2021
    Applicant: Tremeau Pharmaceuticals, Inc.
    Inventors: Raymond D. Skwierczynski, Bradford C. Sippy, Jean-Marie Schneider, Simon H. Drouin, Charles Guerin
  • NOVEL DOSAGE FORMS OF ROFECOXIB AND RELATED METHODS
    Publication number: 20210169845
    Abstract: The subject matter disclosed herein relates to novel doses and dosage forms of rofecoxib having a therapeutic benefit.
    Type: Application
    Filed: February 23, 2021
    Publication date: June 10, 2021
    Applicant: Tremeau Pharmaceuticals, Inc.
    Inventors: Bradford C. Sippy, Raymond D. Skwierczynski, Travis E. Helm
  • NOVEL DOSAGE FORMS OF ROFECOXIB AND RELATED METHODS
    Publication number: 20210137878
    Abstract: The subject matter disclosed herein relates to novel doses and dosage forms of rofecoxib having a therapeutic benefit.
    Type: Application
    Filed: December 18, 2020
    Publication date: May 13, 2021
    Applicant: Tremeau Pharmaceuticals, Inc.
    Inventors: Bradford C. Sippy, Raymond D. Skwierczynski, Travis E. Helm
  • Purified forms of rofecoxib, methods of manufacture and use
    Patent number: 10987337
    Abstract: The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: April 27, 2021
    Assignee: Tremeau Pharmaceuticals, Inc.
    Inventors: Raymond D. Skwierczynski, Bradford C. Sippy, Jean-Marie Schneider, Simon H. Drouin, Charles Guerin
  • Dosage forms of rofecoxib and related methods
    Patent number: 10945992
    Abstract: The subject matter disclosed herein relates to novel doses and dosage forms of rofecoxib having a therapeutic benefit.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: March 16, 2021
    Assignee: Tremeau Pharmaceuticals, Inc.
    Inventors: Bradford C. Sippy, Raymond D. Skwierczynski, Travis E. Helm