Abstract: The present invention provides a fusion protein comprising (1) the extracellular domain of glycoprotein VI or a variant thereof that is functional for binding to collagen and (b) the Fc domain of the immunoglobulin or a function-conservative part thereof, characterized by a polypeptide chain having an amino acid sequence as shown in FIG. 7 and whereby the fusion protein is obtainable by a process which provides the fusion protein in the form of a specific dimer.
Type:
Grant
Filed:
December 10, 2004
Date of Patent:
May 12, 2009
Assignee:
Trigen GmbH
Inventors:
Steffen Massberg, Meinrad Gawaz, Andreas Bültmann, Götz Münch, Martin Ungerer, Mario Peluso
Abstract: The present invention provides a fusion protein comprising (a) the extracellular domain of glycoprotein VI or a variant thereof that is functional for binding to collagen and (b) the Fc domain of an immunoglobulin or a function-conservative part thereof, characterised by a polypeptide chain having an amino acid sequence as shown in FIG. 7 and whereby the fusion protein is obtainable by a process which provides the fusion protein in the form of a specific dimer.
Type:
Grant
Filed:
June 5, 2003
Date of Patent:
April 7, 2009
Assignee:
Trigen GmbH
Inventors:
Steffen Massberg, Meinrad Gawaz, Andreas Bültmann, Götz Münch, Martin Ungerer, Mario Peluso