Abstract: A composition for evaluating a biological condition is disclosed. The composition has (a) a sample composition comprising at least one of: i.) a bodily specimen comprising a target moiety; ii.) a positive control moiety; and iii.) a negative control moiety; (b) an antibody composition comprising at least one of: i.) at least one target antibody; ii.) at least one positive control identifying antibody; and iii.) at least one negative control identifying antibody; and (c) at least one reference composition comprising at least one of: i.) a target signal reference composition; and ii.) a reference identifier composition.
Type:
Application
Filed:
January 8, 2013
Publication date:
September 5, 2013
Applicant:
Trillium Diagnostics, LLC
Inventors:
Bruce H. Davis, Charles Bruce Bagwell, Benjamin Hunsberger
Abstract: The invention relates a method of quantifying CD64 and CD163 expression in leukocytes and, specifically to a kit for use with a flow cytometer including a suspension of quantitative fluorescent microbead standards, fluorescent labeled antibodies directed to CD64 and CD163, and analytical software. The software is used to take information on the microbead suspension and fluorescent labeled antibodies from a flow cytometer and analyse data, smooth curves, calculate new parameters, provide quality control measures and notify of expiration of the assay system.
Type:
Grant
Filed:
November 16, 2011
Date of Patent:
January 29, 2013
Assignee:
Trillium Diagnostics, LLC
Inventors:
Bruce H. Davis, Charles Bruce Bagwell, Benjamin Hunsberger
Abstract: The invention relates a method of quantifying CD64 and CD163 expression in leukocytes and, specifically to a kit for use with a flow cytometer including a suspension of quantitative fluorescent microbead standards, fluorescent labeled antibodies directed to CD64 and CD163, and analytical software. The software is used to take information on the microbead suspension and fluorescent labeled antibodies from a flow cytometer and analyse data, smooth curves, calculate new parameters, provide quality control measures and notify of expiration of the assay system.
Type:
Application
Filed:
November 16, 2011
Publication date:
April 5, 2012
Applicant:
Trillium Diagnostics, LLC
Inventors:
Bruce H. Davis, Charles Bruce Bagwell, Benjamin Hunsberger
Abstract: The invention relates a method of quantifying CD64 and CD163 expression in leukocytes and, specifically to a kit for use with a flow cytometer including a suspension of quantitative fluorescent microbead standards, fluorescent labeled antibodies directed to CD64 and CD163, and analytical software. The software is used to take information on the microbead suspension and fluorescent labeled antibodies from a flow cytometer and analyse data, smooth curves, calculate new parameters, provide quality control measures and notify of expiration of the assay system.
Type:
Grant
Filed:
November 18, 2005
Date of Patent:
February 14, 2012
Assignee:
Trillium Diagnostics, LLC
Inventors:
Bruce H. Davis, Charles Bruce Bagwell, Benjamin Hunsberger
Abstract: The invention relates a method of quantifying CD64 and CD163 expression in leukocytes and, specifically to a kit for use with a flow cytometer including a suspension of quantitative fluorescent microbead standards, fluorescent labeled antibodies directed to CD64 and CD163, and analytical software. The software is used to take information on the microbead suspension and fluorescent labeled antibodies from a flow cytometer and analyse data, smooth curves, calculate new parameters, provide quality control measures and notify of expiration of the assay system.
Type:
Application
Filed:
November 18, 2005
Publication date:
May 7, 2009
Applicant:
Trillium Diagnostics, LLC
Inventors:
Bruce H. Davis, C. B. Bagwell, Benjamin Hunsberger