Patents Assigned to Trineos
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Publication number: 20210137945Abstract: Provided herein is a method for the treatment and/or prophylaxis of a cancer associated with galectin-1. The method includes administering to a subject a pharmaceutical composition that mainly composed of ganoderic acid S (GAS) and ganoderic acid T (GAT). The method further includes administering to the subject another anti-cancer agent before, together with, or after the administration of the present pharmaceutical composition, so as to synergistically suppress the growth of the cancer.Type: ApplicationFiled: November 13, 2019Publication date: May 13, 2021Applicant: TRINEO BIOTECHNOLOGY CO. LTDInventors: Teng-Hai CHEN, Mon-Tarng CHEN, Chien-Yuan WANG, Cheng-Po HUANG, Su-Yu CHEN, Yi-Hsiu LIN, Ssu-Chia WANG, Chih-Yuan LIAO
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Patent number: 10357525Abstract: Disclosed herein is a novel use of a polysaccharide mixture for the treatment of hyperglycemia and/or disorders related thereto (e.g., diabetes mellitus). The polysaccharide mixture comprises about 30-50% (wt %) of ?(1?3) glucan and ?(1?6) glucan, and has a molecular weight of at least 500,000. The polysaccharide mixture may be administered to a subject suffering from hyperglycemia in a dose of about 1 to 1,000 mg/Kg to ameliorate or alleviate symptoms associated with hyperglycemia.Type: GrantFiled: May 31, 2017Date of Patent: July 23, 2019Assignee: TRINEO BIOTECHNOLOGY CO. LTDInventors: Cheng-Po Huang, Cheng-Chiu Tsao, Chao-hsuan Chang, Teng-Hai Chen, Li-Ming Huang, Chieh-Hung Lin
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Publication number: 20180344784Abstract: Disclosed herein is a novel use of a polysaccharide mixture for the treatment of hyperglycemia and/or disorders related thereto (e.g., diabetes mellitus). The polysaccharide mixture comprises about 30-50% (wt %) of ?(1?3) glucan and ?(1?6) glucan, and has a molecular weight of at least 500,000. The polysaccharide mixture may be administered to a subject suffering from hyperglycemia in a dose of about 1 to 1,000 mg/Kg to ameliorate or alleviate symptoms associated with hyperglycemia.Type: ApplicationFiled: May 31, 2017Publication date: December 6, 2018Applicant: TRINEO BIOTECHNOLOGY CO. LTDInventors: Cheng-Po HUANG, Cheng-Chiu TSAO, Chao-hsuan CHANG, Teng-Hai CHEN, Li-Ming HUANG, Chieh-Hung LIN
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Publication number: 20150353595Abstract: Disclosed herein are compositions and methods for the treatment or prophylaxis of a subject having or susceptible to a kidney disease. The method includes the step of administering to the subject a compound of formula (I) in a dose of about 1 to 10 mg/Kg to improve the glomerular filtration rate (GFR) of the subject for at least 4 folds as compared to the GFR of the subject before treatment, The method further includes the step of administering to the subject an effective amount of lucidenic acid C (LAC), lucidenic acid N (LAN), lucidenic acid E2 (LAE2), lucidenic acid A (LAA), and lucidenic acid D2 (LAD2).Type: ApplicationFiled: June 9, 2014Publication date: December 10, 2015Applicant: Trineo Biotechnology Co. LTD.Inventors: Cheng-Po Huang, Teng-Hai Chen, Kuang Dee Chen, Chun-Tao Su
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Patent number: 5215375Abstract: Gas injected into a liquid flowing through a pipeline is sheared to increase the interfacial surface area by a shearing element which consists of an elongate body which can be placed directly inside the conduit, the element having baffles transverse to its center axis, the baffles being apertured with holes less than about 0.5 cm in diameter. In preferred embodiments, the baffles define a series of zig-zag flow paths which promote turbulent flow while also urging the gas bubbles into and through the apertures. The bubbles are thus sheared and agitated at the same time.Type: GrantFiled: April 24, 1991Date of Patent: June 1, 1993Assignee: TrineosInventors: Lee C. Ditzler, Ronald Lemberger, Jerry F. Choy
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Patent number: 5114576Abstract: Biological decontamination and the avoidance of accumulation of dissolved solids are both achieved in captured and recirculated water systems by a continuously operating system involving the use of a chemical filtration unit, removal of dissolved solids as they are concentrated at the filtration unit, a disinfectant treatment, and the protection of the chemical filtration unit from degradation by the disinfectant where necessary.Type: GrantFiled: October 11, 1990Date of Patent: May 19, 1992Assignee: TriNeosInventors: Lee C. Ditzler, Ronald Lemberger, Willam K. McGrane, Jerry F. Choy
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Patent number: 5002739Abstract: An ozone generation cell operating by corona discharge in an annular passage with regions of corona discharge alternating with corona-free regions where cooling takes place is improved by the incorporation of corrugated, deformable heat transfer walls in the corona-free regions. These corrugated walls impart flexibility to the structure, and thereby relieve the strain on the structural components. This permits the heat transfer wall, which is the outer of the two cylinders defining the annular passage, to center the inner of the two cylinders inside it and thus achieve a more uniform gap width in the corona regions. This is of value since the inner cylinder is preferably made of a ceramic material and not perfectly straight. The corrugations also promote turbulent flow in both the coolant medium and the gas mixture in which the ozone is generated.Type: GrantFiled: September 11, 1990Date of Patent: March 26, 1991Assignee: TrineosInventors: Lee C. Ditzler, Jerry F. Choy, Ronald F. Lemberger
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Patent number: 4877588Abstract: Ozone is added to captured water by a method and apparatus which involves corona discharge into an oxygen-containing gas in regions in a generator which alternate with regions where the newly formed ozone is cooled. The alternating corona and cooling regions permit the ozone to form without being thermally decomposed as soon as it is formed. Also disclosed is an overall system and method of controlling the level of dissolved ozone in a body of captured water which modulates the output of an ozone generator in accordance with readings of oxidation-reduction potential in the water.Type: GrantFiled: June 17, 1988Date of Patent: October 31, 1989Assignee: TrineosInventors: Lee C. Ditzler, Ronald F. Lemberger, Cynthia L. Slezak