Abstract: The present disclosure features useful compositions and methods to treat trinucleotide repeat expansion disorders, e.g., in a subject in need thereof. In some aspects, the compositions and methods described herein are useful in the treatment of disorders associated with OGG1 activity.
Type:
Application
Filed:
December 2, 2019
Publication date:
February 9, 2023
Applicant:
Triplet Therapeutics, Inc.
Inventors:
Nessan Anthony BERMINGHAM, Brian R. BETTENCOURT, Peter Edward BIALEK
Abstract: The present disclosure features useful compositions and methods to treat nucleotide repeat expansion disorders, e.g., in a subject in need thereof. In some aspects, the compositions and methods described herein are useful in the treatment of disorders associated with MSH3 activity.
Type:
Grant
Filed:
June 2, 2021
Date of Patent:
August 9, 2022
Assignee:
Triplet Therapeutics, Inc.
Inventors:
Nessan Anthony Bermingham, Brian R. Bettencourt, Pei Ge