Abstract: The present invention relates to methods for predicting T cell epitopes. In particular, the present invention relates to methods for predicting whether modifications in peptides or polypeptides such as tumor-associated neoantigens are immunogenic or not. The methods of the invention are useful, in particular, for the provision of vaccines which are specific for a patient's tumor and, thus, in the context of personalized cancer vaccines.
Type:
Application
Filed:
May 7, 2014
Publication date:
May 5, 2016
Applicants:
BioNTech AG, TROM
Inventors:
Ugur Sahin, Arbel David Tadmor, John Christopher Castle, Sebastian Boegel, Martin Löwer
Abstract: The MONOS vertical memory cell of the present invention allow miniaturization of the memory cell area. The two embodiments of split gate and single gate provide for efficient program and erase modes as well as preventing read disturb in the read mode.
Abstract: The MONOS vertical memory cell of the present invention allow miniaturization of the memory cell area. The two embodiments of split gate and single gate provide for efficient program and erase modes as well as preventing read disturb in the read mode.
Abstract: A method and device for reducing noise and vibrations in a suction pipe (1) in a reaction-type hydropower turbine. The suction pipe (1) comprises one or more nozzles (2) for injection of a working medium through the nozzles (2) into the suction pipe (1). Each nozzle is arranged at an angle ? relative to a horizontal plane perpendicular to the longitudinal axis (4) of an inlet (3) of the suction pipe (1) and at an angle ? relative to a horizontally defined tangent (6) at the point of intersection between each nozzle (2) and the suction pipe (1).
Abstract: A method and device for reducing noise and vibrations in a suction pipe (1) in a reaction-type hydropower turbine. The suction pipe (1) comprises one or more nozzles (2) for injection of a working medium through the nozzles (2) into the suction pipe (1). Each nozzle is arranged at an angle ? relative to a horizontal plane perpendicular to the longitudinal axis (4) of an inlet (3) of the suction pipe (1) and at an angle ? relative to a horizontally defined tangent (6) at the point of intersection between each nozzle (2) and the suction pipe (1).