Patents Assigned to True North Therapeutics, Inc.
  • Anti-complement C1s antibodies and methods of inhibiting complement C1s activity
    Patent number: 9562106
    Abstract: The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. In some embodiments, such anti-complement C1s antibodies inhibit proteolytic activity of C1s. The present disclosure also provides compositions comprising such antibodies, and methods to produce and use such antibodies, nucleic acid molecules, and compositions.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: February 7, 2017
    Assignee: True North Therapeutics, Inc.
    Inventors: Peter Van Vlasselaer, Graham Parry, Nancy E. Stagliano, Sandip Panicker
  • Methods of inhibiting complement C4 activation with anti-complement C1s antibodies
    Patent number: 9562092
    Abstract: The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. The present disclosure also provides compositions comprising such antibodies, and methods to produce and use such antibodies, nucleic acid molecules, and compositions.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: February 7, 2017
    Assignee: True North Therapeutics, Inc.
    Inventors: Peter Van Vlasselaer, Graham Parry, Nancy E. Stagliano, Sandip Panicker
  • Anti-complement C1s antibodies and methods of inhibiting complement C1s activity
    Patent number: 9512233
    Abstract: The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. In some embodiments, such anti-complement C1s antibodies inhibit proteolytic activity of C1s. The present disclosure also provides compositions comprising such antibodies, and methods to produce and use such antibodies, nucleic acid molecules, and compositions.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: December 6, 2016
    Assignee: True North Therapeutics, Inc.
    Inventors: Peter Van Vlasselaer, Graham Parry, Nancy E. Stagliano, Sandip Panicker
  • Methods of inhibiting complement C4 activation with anti-complement C1S antibodies
    Patent number: 9206259
    Abstract: The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. The present disclosure also provides compositions comprising such antibodies, and methods to produce and use such antibodies, nucleic acid molecules, and compositions.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: December 8, 2015
    Assignee: TRUE NORTH THERAPEUTICS, INC.
    Inventors: Peter Van Vlasselaer, Graham Parry, Nancy E. Stagliano, Sandip Panicker
  • Methods of inhibiting activation of complement component C4 with anti-C1s antibodies
    Patent number: 9074004
    Abstract: The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. The present disclosure also provides compositions comprising such antibodies, and methods to produce and use such antibodies, nucleic acid molecules, and compositions.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: July 7, 2015
    Assignee: TRUE NORTH THERAPEUTICS, INC.
    Inventors: Peter Van Vlasselaer, Graham Parry, Nancy E. Stagliano, Sandip Panicker
  • Methods of inhibiting activation of complement component C4 with anti-C1s antibodies
    Patent number: 9074003
    Abstract: The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. The present disclosure also provides compositions comprising such antibodies, and methods to produce and use such antibodies, nucleic acid molecules, and compositions.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: July 7, 2015
    Assignee: TRUE NORTH THERAPEUTICS, INC.
    Inventors: Peter Van Vlasselaer, Graham Parry, Nancy E. Stagliano, Sandip Panicker
  • Anti-complement C1s antibodies
    Patent number: 8945562
    Abstract: The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. The present disclosure also provides compositions comprising such antibodies, and methods to produce and use such antibodies, nucleic acid molecules, and compositions.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: February 3, 2015
    Assignee: True North Therapeutics, Inc.
    Inventors: Peter Van Vlasselaer, Graham Parry, Nancy E. Stagliano, Sandip Panicker
  • Anti-complement C1s
    Patent number: 8877197
    Abstract: The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. The present disclosure also provides compositions comprising such antibodies, and methods to produce and use such antibodies, nucleic acid molecules, and compositions.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: November 4, 2014
    Assignee: True North Therapeutics, Inc.
    Inventors: Peter Van Vlasselaer, Graham Parry, Nancy E. Stagliano, Sandip Panicker