Abstract: The present invention is directed to hemi phorboxazole A: and its stereoisomers, as well as derivatives of hemi phorboxazole A of formula I: wherein ring A is aryl or a 5- or 6-membered heteroaryl optionally substituted with one or more of halogen, —OH, or —C1-6alkyl; and R is —CN, a 5- or 6-membered heteroaryl, or halogen; and the pharmaceutically acceptable salt forms thereof, in addition to methods of using these compounds.
Type:
Application
Filed:
July 23, 2010
Publication date:
January 31, 2013
Applicants:
The Regents of the University of California, The Trustes of The University of Pennsylvania
Inventors:
Amos B. Smith, III, Zhuqing Liu, Anne-Marie L. Hogan, Doralyn S. Dalisay, Tadeusz F. Molinski
Abstract: Novel poly(B-alkenyl-borazines), such as poly(B-vinyl borazine), are useful as precursors to BN ceramics. The poly alkenylborazines, which may advantageously be soluble and easily processed, are prepared by heat treatment of corresponding B-alkenylborazines, which are themselves novel compounds.
Type:
Grant
Filed:
January 21, 1992
Date of Patent:
April 13, 1993
Assignee:
Truste of the University of Pennsylvania