Abstract: The present invention provides a system and single or multi-functional element device that can be inserted and temporarily placed or implanted into a structure having a lumen or hollow space, such as a subject's abdominal cavity to provide therewith access to the site of interest in connection with minimally invasive surgical procedures. The insertable device may be configured such that the functional elements have various degrees of freedom of movement with respect to orienting the functional elements or elements to provide access to the site from multiple and different orientations/perspectives as the procedure dictates, e.g., to provide multiple selectable views of the site, and may provide a stereoscopic view of the site of interest.

Abstract: Systems and methods for suspended polymer photonic crystal (SPPC) cavities and waveguides are disclosed. In one aspect, photonic crystal cavities are provided. An exemplary photonic crystal cavity can include a substrate having a trench. A polymer film can be suspended above the trench thereby forming a gap between the polymer film and the substrate. The polymer film can include a plurality of holes to thereby form at least one optical cavity. The plurality of holes can have a lattice spacing, and each hole can have a radius. The radius and lattice spacing of the plurality of holes can be adapted to increase a gap-midgap ratio. In another aspect, photonic waveguides are provided. In another, methods for fabricating an SPPC are provided. In another, methods for sensing using a polymer photonic crystal ladder cavity are disclosed. In another, methods for optical filtering using an SPPC waveguide-coupled cavity drop filter are disclosed.

Abstract: The present disclosure provides biocompatible scaffold that promotes M1 or M2 macrophage phenotypes so as to increase vascularization or healing. Also provided are methods of treating a subject in need with the scaffolds described here.

Abstract: Methods and systems for capturing carbon dioxide from dilute sources are disclosed. In some embodiments, the methods include the following: (a) directing a first substantially gaseous stream including a first amount of carbon dioxide to a primary scrubber; (b) in the primary scrubber, removing a portion of the first amount of carbon dioxide thereby forming a second substantially gaseous stream including a second amount of carbon dioxide; (c) directing the second substantially gaseous stream to a secondary scrubber; (d) in the secondary scrubber, removing a portion of the second amount of carbon dioxide thereby forming a third substantially gaseous stream; (e) mixing substantially all of the portion of the second amount of carbon dioxide removed in step (d) with the first substantially gaseous stream before it enters the primary scrubber; and (f) repeating steps (a) thru (e).

Abstract: A method is provided for increasing trafficking of endothelial progenitor cells to an ischemic myocardium in a subject's heart comprising administering to the subject's heart an amount of Stromal-Derived Factor-1 (SDF-1).

Abstract: Described is a transgenic mouse with two transgenes, each of which transgene comprises a DNA sequence encoding a dominant negative form of RbAp48 protein, wherein the expression of the dominant negative form of RbAp48 is spatially restricted to the forebrain by a CaM Kinase IIa promoter and wherein the expression of the dominant negative form of RbAp48 is controlled by tetracycline-controlled transcriptional activation. Also provided are methods for evaluating in the transgenic mouse the potential therapeutic effect of an agent for slowing, inhibiting or preventing age-related memory decline in a mammalian subject.

Abstract: Methods to treat certain types of cancer with cyclophilin inhibitors.

Abstract: Methods, systems, and media for inhibiting attacks on embedded devices are provided, in some embodiments, a system for inhibiting on embedded devices is provided, the system comprises a processor that is configured to: identify an embedded device that is configured to provide one or more services to one or more digital processing devices within a communications network; receive a first firmware associated with the embedded device; generate a second firmware that is functionally equivalent to the first firmware by: determining unused code within the first firmware; removing the unused code within the second firmware; and restructuring remaining code portions of the first firmware into memory positions within the second firmware; and inject the second firmware into the embedded device.

Abstract: An interferometer module for quantum processing is described including a substrate having two or more input ports and two or more output ports; multiple photonic pathways embedded in the substrate for conveying photons from the two or more input ports and the two or more output ports; and one or more partial beam splitters embedded in the substrate in a photonic pathway for generating spatial and polarization entanglement.

Abstract: Techniques for obtaining a frequency standard using the crystal field splitting frequency of nitrogen vacancy center in diamond are disclosed. In certain exemplary embodiments, a microwave field is applied to the diamond and optically exciting the diamond under green light. The photoluminescent response of the diamond is measured by a photodetector. The intensity of the photoluminescent response can be used to determine the phase shift between the microwave and the crystal field splitting frequency. The microwave field frequency can be adjusted until the phase shift is below a predetermined threshold, and the microwave frequency can then be output for use as a standard.

Abstract: Methods, systems, and media for identifying similar songs using jumpcodes are provided. In some embodiments, methods for a cover song from a query song are provided, the methods comprising: identifying a query song jumpcode for the query song, wherein the query song jumpcode is indicative of changes in prominent pitch over a portion of the query song; identifying a plurality of reference song jumpcodes for a reference song, wherein each of the reference song jumpcodes is indicative of changes in prominent pitch over a portion of the reference song; determining if the query song jumpcode matches any of the plurality of reference song jumpcodes; and upon determining that the query song jumpcode matches at least one of the plurality of reference song jumpcodes, generating an indication that the reference song is a cover song of the query song.

Abstract: Systems and methods for panoramic imaging are disclosed herein. An exemplary system of the disclosed subject matter for panoramic imaging includes a fisheye lens, a mirror optically coupled to the fisheye lens, and a detector for capturing light incident on the fisheye lens and reflected from the mirror. In some embodiments, the mirror is a spherical mirror.

Abstract: A method for unsupervised anomaly detection, which are algorithms that are designed to process unlabeled data. Data elements are mapped to a feature space which is typically a vector space d. Anomalies are detected by determining which points lies in sparse regions of the feature space. Two feature maps are used for mapping data elements to a feature apace. A first map is a data-dependent normalization feature map which we apply to network connections. A second feature map is a spectrum kernel which we apply to system call traces.

Abstract: The invention is directed to methods and metric suitable for use in determining the solubility, expression and usability of a polypeptide encoded by a nucleic acid sequence. In certain aspects, the invention also relates to methods for introducing modifications in a polypeptide, for example through substitution of one or more codons in the nucleic acid sequence encoding the polypeptide, to increase or decrease the solubility, expression or usability of the polypeptide.

Abstract: The present invention relates to compositions, including membrane permeable complexes, comprising a Caspase 2 activation inhibitory peptide having the amino acid sequence AFDAFC as well as methods of using the same for the treatment of neurodegenerative conditions associated with apoptosis in the central nervous system, such as Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, amyotrophic lateral sclerosis, Huntington's chorea, and Creutzfeld-Jacob disease.

Abstract: Provided are mutant cocaine esterase polypeptides and PEGylated formulations thereof.

Abstract: Systems and methods are presented for content extraction from markup language text. The content extraction process may parse markup language text into a hierarchical data model and then apply one or more filters. Output filters may be used to make the process more versatile. The operation of the content extraction process and the one or more filters may be controlled by one or more settings set by a user, or automatically by a classifier. The classifier may automatically enter settings by classifying markup language text and entering settings based on this classification. Automatic classification may be performed by clustering unclassified markup language texts with previously classified markup language texts.

Abstract: The present invention is based, at least in part, on the discovery of biomarkers identified herein which are associated with cutaneous T-cell lymphoma (CTCL). Accordingly, the present invention provides methods for diagnosing CTCL, e.g., early stage CTCL, including mycosis fungoides (MF) and Sézary syndrome (SS), and to distinguish CTCL from other skin disorders.

Abstract: Apparatus and methods can include an optical waveguide coupled to a photonic crystal comprising a dielectric material, the photonic crystal located on an exterior surface of the optical waveguide and comprising a first surface including a first array of periodic features on or within the dielectric material, the array extending in at least two dimensions and including an effective dielectric permittivity different from the surrounding dielectric material. In an example, the periodic features include a specified lattice constant, the periodic features configured to extract a portion of propagating optical energy from the waveguide through the photonic crystal, the portion determined at least in part by the specified lattice constant.

Abstract: The invention is directed to a isolated a Piscine reovirus associated with HSMI in teleosts, and isolated nucleic acids sequences and peptides thereof. The invention also relates to diagnostic antibodies against antigens derived from Piscine reoviruses. In another aspect, the invention relates to iRNAs which target nucleic acid sequences of Piscine reoviruses. In another aspect, the invention is related to methods for detecting the presence or absence of Piscine reoviruses in an animal.