Abstract: Provided herein are implantable biomedical devices and methods of administering implantable biomedical devices, making implantable biomedical devices, and using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment.
Type:
Application
Filed:
December 24, 2013
Publication date:
June 12, 2014
Applicants:
The Board of Trustees of the University of lllinois, The Trustees of the University of Pennsylvania, Trustees of Tuffs College, Northwestern University
Inventors:
John A. ROGERS, Dae-Hyeong KIM, Fiorenzo OMENETTO, David L. KAPLAN, Brian LITT, Jonathan VIVENTI, Yonggang HUANG, Jason AMSDEN
Abstract: The present invention relates to inhibitors of lipases, such as inhibitors of endothelial lipase, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. The prototype of these inhibitors has lipophilic portion and an electrophilic site.
Type:
Application
Filed:
October 28, 2011
Publication date:
April 26, 2012
Applicant:
Trustees of Tuffs College
Inventors:
William W. Bachovchin, Hung-Sen Lai, Daniel P. O'Connell