Abstract: Provided is an organic-inorganic hybrid composite of a polymerized cyclic nitroxide radical compound and inorganic nanoparticles. Such a composite is capable, for example, of maintaining a stable nanoparticle shape in gastric fluid, and can be used by itself or as a carrier for delivery of another drug to the intestines.

Abstract: Cymbopogon schoenanthus is used in folk medicine in North-African for the treatment of rheumatism and to diminish fever. However, whether it possesses anti-stress properties had not previously been established in vivo. Disclosed herein are data demonstrating the effectiveness of C. schoenanthus ethanol extracts on stressors in vitro (heat shock and oxidative stress) and on stressors in vivo (forced swimming test and tail suspension test). Moreover, disclosed are statistically significant anti-stress effects in vivo which occur in a dose-dependent manner. Additionally, the effects of C. schoenanthus ethanol extract exposure is shown to be comparable to a commercially-available antidepressant drug. Accordingly, C. schoenanthus ethanol extracts are useful in new compositions and methods for treating or ameliorating emotional-psychological stress.