Abstract: A unit verification method to be performed on a unit under test (UUT) comprises connecting a verification device to the UUT. The verification device applies a set of challenge signals to the UUT and then measures the responses of the UUT to the challenge signals. The responses of the UUT are based on the challenge signals and the physical properties of the UUT. A registration key is generated based on the measured responses and is stored. The registration key is unique to the UUT.

Abstract: There is provided a sample ejection system for ejecting a sample from a flow of fluid, the system comprises: a fluid flow channel for receiving, in use, the flow of fluid; a fluid inlet channel connected to the flow channel and arranged to receive, in use, pressurised fluid; a fluid outlet channel connected to the flow channel at a location downstream in the flow direction of the flow of fluid and comprises an outlet. The system is arranged such that, in use, pressurised fluid is applied to the fluid flow channel via the fluid inlet channel to drive fluid from the region of the fluid flow channel between the fluid inlet and outlet channels through the fluid outlet channel and out of the outlet.

Abstract: A droplet dispenser comprises a chamber (3) with a fluid inlet valve (2) and a fluid outlet valve (4). The chamber (3) is arranged such that the volume of the chamber may be varied in use to cause fluid to be alternately drawn in to the chamber (3) through the inlet valve (2) then subsequently expelled from the chamber through the outlet valve (4) to dispense a droplet. The droplet dispenser is capable of dispensing from an open reservoir and one may change the dispensed drop volume simply and easily. The droplet dispenser can also handle liquids which are normally seen as difficult to dispense, such as cyanoacrylate adhesives.

Abstract: A single junction sorter for a microfluidic particle sorter, the single-junction sorter comprising: an input channel, configured to receive a fluid containing particles; an output sort channel and an output waste channel, each connected to the input channel for receiving the fluid therefrom; a bubble generator, operable to selectively displace the fluid around a particle to be sorted and thereby to create a transient flow of the fluid in the input channel; and a vortex element, configured to cause a vortex in the transient flow in order to direct the particle to be sorted into the output sort channel.

Abstract: A counting mechanism (100) for a dispenser comprising: a first and a second housing part (110, 120) that are rotatable relative to each other; and a counting ring (130) disposed between the housing parts. The first housing part has a protrusion (111) which abuts the counting ring, holding a portion of the counting ring in contact with the second housing part. The relative rotation of the housing parts causes the protrusion to slide against the surface of the counting ring to drive a rolling movement of the counting ring around the circumference of the second housing part, such that a predefined rotation of the housing parts produces an incremental rotational displacement between the counting ring and second housing part to record a count. The counting mechanism provides a large gear reduction ratio in a compact form which is straightforward to manufacture and provides an accurate and reliable record of counts.

Abstract: A cap and seal system for a liquid medicament container. The system comprises a cap formed from a substantially rigid material, and has a retention component integrally formed therewith. A seal is formed from a material which is less hard than the cap and positioned within the cap such that, when the retaining component retains the cap on a container in use the seal is positioned such that it forms a fluid tight seal between the cap and the container. A recess is formed in the seal through which a liquid outlet channel can pass in use to access the contents of the container via the cap and the seal.

Abstract: A physically unclonable function (PUF) device comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least a portion of each of the conductors, and circuitry applies an electrical challenge signal to at least one of the conductors and for receiving an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.

Abstract: A medicament delivery device for dispensing discrete doses of medicament comprises: first and second medicament carriers each comprising said doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer; first and second opening mechanisms each arranged to handle a respective one of the first and second medicament carriers and to open each compartment of the respective medicament carrier by separating the sealing layer from the carrier strip as the medicament carrier is advanced through the device; a take-up spool arranged to wind the separated sealing layers thereon such as to maintain the separated sealing layers in tension, each separated sealing layer having a path of travel between a respective one of the first and second opening mechanisms and the take-up spool; and a tension control element in contact with each of the separated sealing layers, wherein at least a part of the tension control element is arranged to be movable by a biasi

Abstract: A consumable container for filling with a fluid in a bioprocessing process. The container comprises one or more sealable, removable portions, such that one or more samples of the fluid may be taken by sealing and removing one or more of said portions.

Abstract: A manifold for a medicament delivery device configured to deliver discrete doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer to form a medicament carrier, the manifold comprising: at least one opening mechanism comprising a release member arranged to engage between the carrier strip and the sealing layer of a medicament carrier so as to separate the sealing layer from the carrier strip and thereby open a compartment of the medicament carrier as it is advanced into an entrainment position; wherein the release member includes a surface configured to cover the opened compartment when in the entrainment position so as substantially to contain the medicament dose of said opened compartment.

Abstract: A device for releasing discrete doses of medicament carried in a plurality of spaced-apart compartments on a medicament carrier, each compartment being arranged in a carrier strip and sealed by a sealing layer, the device comprising: a release mechanism arranged to engage between the carrier strip and the sealing layer so as to unseal at least a portion of the compartment and expose the medicament dose contained therein, wherein the release mechanism preferably covers said exposed compartment in place of the sealing layer.

Abstract: The present invention provides a device with a pressure control system and methods for controlling the application of negative pressure to an external surface of an individual for creating and/or maintaining patency of the upper airway passage. The device is configured to fit under the chin of a subject at an external location corresponding approximately with the subject's internal soft tissue associated with the neck's anterior triangle. The pressure control system contains control module elements that may include circuit board elements, digital output barometer elements, sensor elements, processing elements and memory elements to optimize device function and safety of the device through regulation of the flow rate of the air pump.

Abstract: An acoustic sensor, comprising: a side wall, closed by first and second end walls to form a substantially cylindrical cavity for containing a fluid, wherein a radius, a, of the cavity and an axial height, h, of the cavity satisfies the inequality a/h is greater than 1.

Abstract: An apparatus for inductive temperature sensing comprises a coil configuration, a target, and an impedance measurement circuit. The target has a non-zero conductivity and susceptibility and the impedance measurement circuit measures the apparent inductance of the coil configuration at a measurement frequency close to the crossover frequency to provide an indication of temperature of the target.

Abstract: A nozzle plate (201) for use in a liquid droplet production apparatus and such apparatus, the nozzle plate comprising a flexible substrate having a linear array of nozzles that extend through said plate, said nozzles being arranged in at least one line, forming thereby a nozzle-bearing region, wherein the substrate is curved so as to impart an increased longitudinal stiffness to it. The apparatus comprises a piezo actuator (202, 203), which may have slots (211) separating fingers acting on the nozzle plate (201). The nozzle plate may be separable form the actuator.

Abstract: A counting mechanism (100) for a dispenser comprising: a first and a second housing part (110, 120) that are rotatable relative to each other; and a counting ring (130) disposed between the housing parts. The first housing part has a protrusion (111) which abuts the counting ring, holding a portion of the counting ring in contact with the second housing part. The relative rotation of the housing parts causes the protrusion to slide against the surface of the counting ring to drive a rolling movement of the counting ring around the circumference of the second housing part, such that a predefined rotation of the housing parts produces an incremental rotational displacement between the counting ring and second housing part to record a count. The counting mechanism provides a large gear reduction ratio in a compact form which is straightforward to manufacture and provides an accurate and reliable record of counts.

Abstract: The present invention provides a device with a pressure control system and methods for controlling the application of negative pressure to an external surface of an individual for creating and/or maintaining patency of the upper airway passage. The device is configured to fit under the chin of a subject at an external location corresponding approximately with the subject's internal soft tissue associated with the neck's anterior triangle. The pressure control system contains control module elements that may include circuit board elements, digital output barometer elements, sensor elements, processing elements and memory elements to optimize device function and safety of the device through regulation of the flow rate of the air pump.

Abstract: A sample preparation cartridge for use with a sample preparation device, the cartridge includes a housing defining plural separate segments, at least one of said segments comprising a fixed section of a pipette component; and a moveable head comprising a pipette tip, the head being configured, in use, to be moved between a position in which the pipette tip is in sealed engagement with the fixed section of pipette component and a position in which pipette tip is positioned adjacent to another of said plural segments. With the present invention a disposable sample preparation cartridge and corresponding analytical reader can be provided in a very cost effective and simple manner whilst still ensuring high quality sample preparation for analysis.

Abstract: The present invention relates to a method for the deformation and/or fragmentation of a cell, spore or virus, the method comprising: (i) bringing a liquid sample containing the cell, spore or virus into contact with a first surface of a vibratable plate having at least one aperture, and causing the plate to vibrate; and (ii) passing the sample of the cell, spore or virus through the at least one aperture in the vibrating plate so as to cause deformation and/or fragmentation of the cell, spore or virus. It also concerns a device for carrying out the method.

Abstract: There is provided A method for producing an electrical impedance tomographic image of an acoustic field within a fluid, comprising the steps of: a) positioning a plurality of electrodes within a fluid; b) applying an electrical signal to each electrode within a first subset of electrodes, wherein the electrical signal applied to each electrode has a different carrier frequency and/or phase; c) measuring the electrical potential at each electrode within a second subset of electrodes; and d) processing the measured data to provide an acoustic map of the acoustic field at the required acoustic frequencies. There is also provided a system for producing an electrical impedance tomographic image of an acoustic field within a fluid using the method of any preceding claim, comprising a plurality of electrodes, a signal generator adapted to perform step (b), a device adapted to perform step (c), and a processor adapted to perform step (d).