Abstract: The present invention relates to a method for the production of a stable biodegradable, high water absorbable ?-polyglutamic acid (?-PGA) hydrogel by directly cross-linking (A) a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof; and/or (B) a microbial culture broth containing a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof, with a cross-linker comprising a compound having three or more functional groups or a mixture of a compound having three or more functional groups and a compound having two functional groups, wherein each of the functional groups can react with a carboxylic group (—COOH), carboxylate group (—COO?), aldehyde group (—CHO), hydroxyl (—OH), carbonyl group (—CO), sulfone group (—SO2), amino group (—NH2) or nitro gro
Type:
Grant
Filed:
March 13, 2008
Date of Patent:
September 7, 2010
Assignee:
Tung Hai Biotechnology Corporation
Inventors:
Guan-Heui Ho, Tou-Hsiung Yang, Kung-Hsiang Yang
Abstract: The present invention relates to a method for the production of a stable biodegradable, high water absorbable ?-polyglutamic acid (?-PGA) hydrogel by directly cross-linking (A) a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof; and/or (B) a microbial culture broth containing a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof, with a cross-linker comprising a compound having three or more functional groups or a mixture of a compound having three or more functional groups and a compound having two functional groups, wherein each of the functional groups can react with a carboxylic group (—COOH), carboxylate group (—COO?), aldehyde group (—CHO), hydroxyl (—OH), carbonyl group (—CO), sulfone group (—SO2), amino group (—NH2) or nitro gro
Type:
Grant
Filed:
March 13, 2008
Date of Patent:
July 20, 2010
Assignee:
Tung Hai Biotechnology Corporation
Inventors:
Guan-Heui Ho, Tou-Hsiung Yang, Kung-Hsiang Yang
Abstract: The present invention relates to a dietary product comprising ?-polyglutamic acid (?-PGA, H form), and/or one or more of its salts (i.e., ?-polyglutamate in Na+ form, ?-polyglutamate in K+ form, ?-polyglutamate in NH4+ form, ?-polyglutamate in Mg++ form, and ?-polyglutamate in Ca++ form) for use as a nutrition supplement.
Type:
Grant
Filed:
September 12, 2005
Date of Patent:
December 15, 2009
Assignee:
Tung Hai Biotechnology Corporation
Inventors:
Guan-Huei Ho, Tou-Hsiung Yang, Jeng Yang
Abstract: The present invention relates to a method for removing a heavy metal from and/or dissolving calcium and/or magnesium scales in water or an aqueous system comprising using ?-polyglutamic acid (?-PGA, H form), and/or one or more of its salts (i.e., ?-polyglutamate in Na+ form, ?-polyglutamate in K+ form, and ?-polyglutamate in NH4+ form) and/or ?-polyglutamate hydrogel as chelating agents for removing heavy metals and/or dissolving agents for removing calcium and/or magnesium scales from water or the aqueous system.
Type:
Grant
Filed:
May 16, 2006
Date of Patent:
January 20, 2009
Assignee:
Tung Hai Biotechnology Corporation
Inventors:
Guan-Huei Ho, Jeng Yang, Tou-Hsiung Yang
Abstract: The present invention relates to a method for the production of a stable biodegradable, high water absorbable ?-polyglutamic acid (?-PGA) hydrogel by directly cross-linking (A) a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof; and/or (B) a microbial culture broth containing a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof, with a cross-linker comprising a compound having three or more functional groups or a mixture of a compound having three or more functional groups and a compound having two functional groups, wherein each of the functional groups can react with a carboxylic group (—COOH), carboxylate group (—COO?), aldehyde group (—CHO), hydroxyl (—OH), carbonyl group (—CO), sulfone group (—SO2), amino group (—NH2) or nitro gro
Type:
Application
Filed:
March 13, 2008
Publication date:
July 3, 2008
Applicant:
TUNG HAI BIOTECHNOLOGY CORPORATION
Inventors:
Guan-Heui Ho, Tou-Hsiung Yang, Kung-Hsiang Yang
Abstract: The present invention relates to a method for the production of a stable biodegradable, high water absorbable ?-polyglutamic acid (?-PGA) hydrogel by directly cross-linking (A) a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof; and/or (B) a microbial culture broth containing a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof, with a cross-linker comprising a compound having three or more functional groups or a mixture of a compound having three or more functional groups and a compound having two functional groups, wherein each of the functional groups can react with a carboxylic group (—COOH), carboxylate group (—COO?), aldehyde group (—CHO), hydroxyl (—OH), carbonyl group (—CO), sulfone group (—SO2), amino group (—NH2) or nitro gro
Type:
Application
Filed:
March 13, 2008
Publication date:
July 3, 2008
Applicant:
TUNG HAI BIOTECHNOLOGY CORPORATION
Inventors:
Guan-Huei Ho, Tou-Hsiung Yang, Kung-Hsiang Yang
Abstract: The present invention relates to a method for the production of a stable biodegradable, high water absorbable ?-polyglutamic acid (?-PGA) hydrogel by directly cross-linking (A) a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof; and/or (B) a microbial culture broth containing a ?-polyglutamic acid (?-PGA), a ?-polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof, with a cross-linker comprising a compound having three or more functional groups or a mixture of a compound having three or more functional groups and a compound having two functional groups, wherein each of the functional groups can react with a carboxylic group (—COOH), carboxylate group (—COO?), aldehyde group (—CHO), hydroxyl (—OH), carbonyl group (—CO), sulfone group (—SO2), amino group (—NH2) or nitro gr
Type:
Grant
Filed:
December 19, 2003
Date of Patent:
April 29, 2008
Assignee:
Tung Hai Biotechnology Corporation
Inventors:
Guan-Huei Ho, Tou-Hsiung Yang, Kung-Hsiang Yang
Abstract: The present invention relates to a method for removing a heavy metal from and/or dissolving calcium and/or magnesium scales in water or an aqueous system comprising using ?-polyglutamic acid (?-PGA, H form), and/or one or more of its salts (i.e., ?-polyglutamate in Na+ form, ?-polyglutamate in K+ form, and ?-polyglutamate in NH4+ form) and/or ?-polyglutamate hydrogel as chelating agents for removing heavy metals and/or dissolving agents for removing calcium and/or magnesium scales from water or the aqueous system.
Type:
Application
Filed:
May 16, 2006
Publication date:
June 7, 2007
Applicant:
Tung Hai Biotechnology Corporation
Inventors:
Guan-Huei Ho, Jeng Yang, Tou-Hsiung Yang