Abstract: Disclosed are peptides having activity against receptor CXCR3 are disclosed that exhibit activity in preventing the formation of new vessels and activity in mediating the dissociation of newly-formed vessels and resolving of wounds in the later stages of wound healing. Preferred peptides are derived from the ?-helix portion IP-10 (CXCL10) or from IP-9 (CXCL11), are nontoxic, and smaller than naturally occurring peptides, making them useful in therapies against diseases or disease states marked by unwanted angiogenesis, including tumorogenic diseases such as cancers, and in healing of chronic wounds.

Abstract: Lytic peptides, including fusion peptides of lytic peptides conjugated with luteinizing hormone-releasing hormone or modified versions thereof to target luteinizing hormone-releasing hormone receptors, are disclosed. The lytic peptides show anti-proliferative activity against human prostate cancer cell lines, but are nontoxic to normal primary human prostate epithelial cells or to bone marrow stromal cells in co-culture. The lytic peptides have specificity for and anti-proliferative activity against prostate cancer tumor cells, and low toxicity for normal prostate cells, making the peptides useful in therapies for prostate cancer.

Abstract: Lytic peptides, including fusion peptides of lytic peptides conjugated with luteinizing hormone-releasing hormone or modified versions thereof to target luteinizing hormone-releasing hormone receptors, are disclosed. The lytic peptides show anti-proliferative activity against human prostate cancer cell lines, but are nontoxic to normal primary human prostate epithelial cells or to bone marrow stromal cells in co-culture. The lytic peptides have specificity for and anti-proliferative activity against prostate cancer tumor cells, and low toxicity for normal prostate cells, making the peptides useful in therapies for prostate cancer.

Abstract: A hydroponic system for growing sweet potatoes and other root and tuber crops includes a growing channel incorporating a movable root contact/pressure plate assembly. The assembly consists of a flat, rigid PVC plate in which holes for inserting plants are drilled and a flexible vinyl film which is secured along the length of each side edge of the plate, by means of pressure fit connectors. The assembly is secured to the top edges of a growing channel, again by pressure fit connectors. The flexible film suspends the plate near and parallel to the bottom of the growing channel, with the flexibility of the film allowing upward movement of the plate within the channel as the plant roots grow. The assembly provides contact and pressure to the plant roots inside the growing channel thereby promoting enlargement of the roots. This enlargement causes the assembly to move upwardly, thereby maintaining the desired pressure conditions during growth. A suitable nutrient solution is supplied in the growing channel.

Abstract: A hydroponic system for growing sweet potatoes and other root and tuber crops includes a growing channel incorporating a movable root contact/pressure plate assembly. The assembly consists of a flat, rigid PVC plate in which holes for inserting plants are drilled and a flexible vinyl film which is secured along the length of each side edge of the plate, by means of pressure fit connectors. The assembly is secured to the top edges of a growing channel, again by pressure fit connectors. The flexible film suspends the plate near and parallel to the bottom of the growing channel, with the flexibility of the film allowing upward movement of the plate within the channel as the plant roots grow. The assembly provides contact and pressure to the plant roots inside the growing channel thereby promoting enlargement of the roots. This enlargement causes the assembly to move upwardly, thereby maintaining the desired pressure conditions during growth. A suitable nutrient solution is suppplied in the growing channel.