Patents Assigned to Tuskegee University
  • Publication number: 20200144524
    Abstract: A photovoltaic cell includes a substrate layer, an anode layer on the substrate layer, an active layer on the anode layer, and a cathode layer on the active layer, wherein the active layer comprises a plurality of disparately sized n-type and p-type nano-particles of different semiconductor materials randomly distributed in a conductive polymer blend. The n-type nano-particles can include either ZnO or In2O3 nano-particles, and the p-type nano-particles can include either NiO or La2O3 nano-particles. The conductive polymer blend can include P3HT. The bandgaps of the nano-particles have corresponding energies ranging from the near ultraviolet to the far infrared.
    Type: Application
    Filed: December 5, 2019
    Publication date: May 7, 2020
    Applicant: Tuskegee University
    Inventors: Naga Korivi, Kalyan Das
  • Patent number: 10583417
    Abstract: A water filtration system is provided that comprises a combination of two components: silver nanoparticles immobilized on a porous carbon solid matrix and calcium carbonate silver nanoparticles. The silver nanoparticles immobilized on the porous carbon solid matrix are prepared in a one-step wet ball milling process that does not use an environmentally hazardous reducing agent or an organic stabilizer. The calcium carbonate in the calcium carbonate silver nanoparticles is preferably isolated from egg shells. The two filter components can be present in any ratio but an approximate 50:50 ratio is preferred. Also provided is an in situ method of preparing silver nanoparticles on active charcoal. Powdered activated charcoal and silver nitrate are mixed together in a mixture of ethanol and water to form a charcoal-silver nitrate solution which is then subjected to ball milling in the presence of polypropylene glycol to produce silver nanoparticles on active charcoal.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: March 10, 2020
    Assignee: TUSKEGEE UNIVERSITY
    Inventors: Vijaya Rangari, Boniface Tiimob, Vitus Apalangya, Shaik Jeelani, Temesgen Samuel
  • Publication number: 20200022721
    Abstract: A handle system includes a body extending between a first end and a second end. The handle system also includes a slot extending, at least partially, in the body, the slot forming a cavity. The handle system further includes a carrier arranged, at least partially, within the slot, the carrier further comprising a friction locker and at least one arm coupled to the friction locker, the at least one arm being rotatable about the friction locker. The handle system also includes a cap arranged on at least one of the first end or the second end. The handle system further includes a blade coupled to the at least one arm, the blade being rotatable about the axis between a retracted position where the blade is positioned within the slot and an extended position where the blade extends outwardly from the body.
    Type: Application
    Filed: July 18, 2019
    Publication date: January 23, 2020
    Applicant: TUSKEGEE UNIVERSITY
    Inventors: Deidre Quinn-Gorham, Sharanabasaweshwara Asundi, Jimesh Bhagatji
  • Publication number: 20200017904
    Abstract: Disclosed are novel genetic arrays for use in the molecular detection of multiple Salmonella serovars, common food-borne and water-borne pathogens. The arrays may be used to simultaneously detect multiple food safety Salmonella serovars. The multiplex-detection methods have improved sensitivity and specificity for the detection of multiple high-impact food-borne pathogens simultaneously. Real-time PCR assaying techniques using such serovars include microarrays.
    Type: Application
    Filed: June 4, 2019
    Publication date: January 16, 2020
    Applicant: Tuskegee University
    Inventors: Woubit ABDELA, Khaled ALDHAMI, Sayma AFROJ, Temesgen SAMUEL, Gopal REDDY
  • Publication number: 20190310223
    Abstract: A general methodology for the development of sensitive and selective sensors that can achieve a low cost detection of glucose without using enzymes is disclosed. The method uses carbon nanofiber (CNF) array electrodes for the electrochemical detection of glucose. CNFs grown by plasma enhanced chemical vapor deposition (PECVD) with diameters ranging from 13-160 nm and a height of approximately one micrometer are preferred. The CNFs have a sensitivity of 2.7 ?A/mM cm2 and detection limit of 2 mM. Also provided are methods of preparing the CNF sensors and kit components. Methods of using such CNF sensors for detecting target agents, particularly glucose, are also provided.
    Type: Application
    Filed: March 26, 2019
    Publication date: October 10, 2019
    Applicant: Tuskegee University
    Inventors: Tamara Floyd SMITH, Julaunica TIGNER, Jessica KOEHNE
  • Publication number: 20190298802
    Abstract: Interferon-?-inducible protein 10 (IP-10) peptides, IP-10 peptide variants and in silico designed C—X—C chemokine receptor 3 (CXCR3) peptide agonists are described. The small peptides can be used for inhibiting pathological tissue remodeling and treating fibrosis in a subject, such as a subject with fibrosis of the heart, lung, liver, kidney or skin. The peptide agonists can also be used to treat cardiovascular disease, including myocardial infarction and ischemia-reperfusion injury. Also described are in silico designed peptide antagonists that bind CXCR3 or ligands of CXCR3. These antagonist peptides block CXCR3 signaling by disrupting interaction of CXCR3 with its ligand. Antagonist peptides can be used, for example, to treat myocarditis and atherosclerosis. In additional embodiments agonists and antagonists of CXCR4 are disclosed.
    Type: Application
    Filed: March 29, 2019
    Publication date: October 3, 2019
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, Tuskegee University, The University of North Carolina at Chapel Hill, The United States of America as represented by the Department of Veterans Affairs
    Inventors: Cecelia C. Yates-Binder, Jesse Jaynes, Monte S. Willis, Richard J. Bodnar, Zariel I. Johnson
  • Publication number: 20190211777
    Abstract: Embodiments of the present disclosure include an injection system. The injection system includes a Resonance Enhanced Microjet (REM) nozzle. The REM nozzles includes a REM nozzle block, the REM nozzle block having an inlet formed in a top and an outlet formed in a bottom, the inlet and outlet being fluid coupled together. The REM nozzle also includes one or more micronozzles positioned about the outlet, the one or more micronozzles having an outlet and being positioned at an angle relative to the bottom. Additionally, the REM nozzle includes an inlet conduit coupled to the REM nozzle block, the inlet conduit being fluidly coupled to the one or more micronozzles. The injection system also includes a source arranged proximate the top, the source directing a source jet of fluid into the inlet. The injection system includes a fuel supply fluidly coupled to the inlet conduit. Such a system can inject a fuel entrained in an oxidizer pulsing at very high-frequency.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 11, 2019
    Applicant: TUSKEGEE UNIVERSITY
    Inventor: John SOLOMON
  • Publication number: 20190203001
    Abstract: A biopolymer film is provided that comprises a combination of: crystalline nano cellulose (CNC)/esterified crystalline nano cellulose (ECNC) reinforced with chitosan. The two polymer components can be present in any ratio but an approximate CNC to ECNC 70:30 ratio is preferred. The chitosan component is derived from exoskeletons of crustaceans. Also provided are methods of preparing biopolymer film and preparing food packaging components from said biopolymer film. The CNC/ECNC mixture is dissolved in an ethanol solution and the chitin is dissolved in acetic acid and mixed together to form a polymer blend.
    Type: Application
    Filed: January 3, 2019
    Publication date: July 4, 2019
    Applicant: TUSKEGEE UNIVERSITY
    Inventors: Vijaya K. RANGARI, Samia ISLAM, Woubit ABDELA
  • Patent number: 10295021
    Abstract: A case-emphasized propulsion method improves vehicle fuel efficiency. The ratio of the most-used speed to the most-desired speed of an IC engine is employed to control the engine to always run at its optimal working state with an efficient single-stage gear transmission. The propulsion method used with different brands of IC engines demonstrates a reduction in fuel consumption between 5 and 39%. An n-ratio automatic single-stage gear transmission implements the propulsion method. The transmission design executes the proposed propulsion method as well a continuous transmission, but it can also increase the propulsion efficiency about 8 to 18% when applied to replace traditional automatic transmissions or continuously variable transmissions in vehicle drivetrains.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: May 21, 2019
    Assignee: Tuskegee University
    Inventor: ShaoWei Gong
  • Publication number: 20190048147
    Abstract: The invention relates to a method of manufacturing a nanocellulosic composition comprising cellulose nanoparticles and/or nanoparticles. The nanocellulosic compositions are useful in the manufacturing of biodegradable plastics. The invention also includes a method of manufacturing biodegradable plastics using such nanocellulosic compositions.
    Type: Application
    Filed: July 5, 2018
    Publication date: February 14, 2019
    Applicant: TUSKEGEE UNIVERSITY
    Inventors: Michael L. CURRY, Donald WHITE
  • Publication number: 20190023896
    Abstract: A biopolymer blend is provided that comprises a combination of three components: poly (butylene adipate-co-terephthalate) (PBAT); agriculture sourced polylactic acid (PLA); and engineered proteinaceous eggshell nanoparticles. The two polymer components can be present in any ratio but an approximate 70:30 ratio is preferred. The engineered proteinaceous eggshell nanoparticles are preferably about 10-25 nanometers. Also provided are methods of preparing biopolymer film and packaging components. Pelleted poly (butylene adipate-co-terephthalate) and agriculture sourced polylactic acid (PLA) are dissolved in chloroform and mixed together to form a polymer blend, and engineered proteinaceous eggshell nanoparticles are incorporated into the polymer blend, which is then extruded to create a biopolymer film or component.
    Type: Application
    Filed: July 19, 2018
    Publication date: January 24, 2019
    Applicant: TUSKEGEE UNIVERSITY
    Inventors: Vijaya RANGARI, Boniface TIIMOB
  • Publication number: 20180339914
    Abstract: This invention relates to cost-effective methods for synthesizing metallic nanoparticles in high yield using non-dendrimeric branched polymeric templates, such as branched polyethyleneimine. This invention also provides a high-throughput apparatus for synthesizing metallic nanoparticles under conditions that produce less waste than conventional nanoparticle synthesis methods. Also provided are metallic nanoparticles and multi-metallic nanoparticle compositions made by methods and high-throughput apparatus of the invention.
    Type: Application
    Filed: May 23, 2018
    Publication date: November 29, 2018
    Applicant: TUSKEGEE UNIVERSITY
    Inventors: Michael L. CURRY, Aiesha L. ETHRIDGE, Demetrius FINLEY
  • Publication number: 20180305228
    Abstract: A water filtration system is provided that comprises a combination of two components: silver nanoparticles immobilized on a porous carbon solid matrix and calcium carbonate silver nanoparticles. The silver nanoparticles immobilized on the porous carbon solid matrix are prepared in a one-step wet ball milling process that does not use an environmentally hazardous reducing agent or an organic stabilizer. The calcium carbonate in the calcium carbonate silver nanoparticles is preferably isolated from egg shells. The two filter components can be present in any ratio but an approximate 50:50 ratio is preferred. Also provided is an in situ method of preparing silver nanoparticles on active charcoal. Powdered activated charcoal and silver nitrate are mixed together in a mixture of ethanol and water to form a charcoal-silver nitrate solution which is then subjected to ball milling in the presence of polypropylene to produce silver nanoparticles on active charcoal.
    Type: Application
    Filed: April 20, 2017
    Publication date: October 25, 2018
    Applicant: TUSKEGEE UNIVERSITY
    Inventors: Vijaya Rangari, Boniface Tiimob, Vitus Apalangya, Shaik Jeelani, Temesgen Samuel
  • Patent number: 9877949
    Abstract: Methods for inhibiting cancer cell proliferation and killing cancer cells are disclosed. Such methods comprise treating cancer cells with an indole compound having the structure of formula (I): wherein R is defined herein.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: January 30, 2018
    Assignee: TUSKEGEE UNIVERSITY
    Inventors: Temesgen Samuel, Teshome Yehualaeshet, Tesfaye Serbessa, Khalda Fadlalla
  • Patent number: 9434976
    Abstract: The invention relates to a method of determining whether a live microbe, such as bacteria, is present in a test sample.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: September 6, 2016
    Assignees: TUSKEGEE UNIVERSITY
    Inventors: Teshome Yehualaeshet, Temesgen Samuel, Woubit Abdela, Tsegaye Habtemariam
  • Patent number: 9358628
    Abstract: A multi-pass gas metal arc weld (“GMAW”) approach is used for in-situ repair of railhead defects. A defect is removed via machining a perpendicular slot or grove in the railhead leaving the web and base unaltered. A sufficient number of GMAW passes are used to fill the slot using a weld material suitable for the particular type of parent steel, and excess weldment can be removed. Optionally, for pearlitic steel rails post-weld heat treatment can be used to cause austenization and/or quenching of the weld. The weld heat inputs and other parameters are controlled to avoid ductile and brittle fracture related morphologies.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: June 7, 2016
    Assignee: TUSKEGEE UNIVERSITY A UNIVERSITY OF ALABAMA
    Inventor: Heshmat Aglan
  • Publication number: 20160111668
    Abstract: A photovoltaic cell includes a substrate layer, an anode layer on the substrate layer, an active layer on the anode layer, and a cathode layer on the active layer, wherein the active layer comprises a plurality of disparately sized n-type and p-type nano-particles of different semiconductor materials randomly distributed in a conductive polymer blend. The n-type nano-particles can include either ZnO or In2O3 nano-particles, and the p-type nano-particles can include either NiO or La2O3 nano-particles. The conductive polymer blend can include P3HT. The bandgaps of the nano-particles have corresponding energies ranging from the near ultraviolet to the far infrared.
    Type: Application
    Filed: September 30, 2015
    Publication date: April 21, 2016
    Applicant: Tuskegee University
    Inventors: Naga Korivi, Kalyan Das
  • Publication number: 20150232633
    Abstract: Structured films containing multi-walled carbon nanotubes (“MWCNTs”) have enhanced mechanical performance in terms of strength, fracture resistance, and creep recovery of polyimide (“PI”) films. Preferably, the loadings of MWCNTs can be in the range of 0.1 wt % to 0.5 wt %. The strength of the new PI films dried at 60° C. increased by 55% and 72% for 0.1 wt % MWCNT and 0.5 wt % MWCNT loadings, respectively, while the fracture resistance increased by 23% for the 0.1 wt % MWCNTs and then decreases at a loading of 0.5 wt % MWCNTs. The films can be advantageously be created by managing a corresponding shift in the annealing temperature at which the maximum strength occurs as the MWCNT loadings increase.
    Type: Application
    Filed: April 28, 2015
    Publication date: August 20, 2015
    Applicant: TUSKEGEE UNIVERSITY
    Inventor: Heshmat Aglan
  • Publication number: 20150164860
    Abstract: Methods for inhibiting cancer cell proliferation and killing cancer cells are disclosed. Such methods comprise treating cancer cells with an indole compound having the structure of formula (I): wherein R is defined herein.
    Type: Application
    Filed: December 12, 2014
    Publication date: June 18, 2015
    Applicant: TUSKEGEE UNIVERSITY
    Inventors: Temesgen Samuel, Teshome Yehualaeshet, Tesfaye Serbessa, Khalda Fadlalla
  • Patent number: 9034426
    Abstract: Structured films containing multi-walled carbon nanotubes (“MWCNTs”) have enhanced mechanical performance in terms of strength, fracture resistance, and creep recovery of polyimide (“PI”) films. Preferably, the loadings of MWCNTs can be in the range of 0.1 wt % to 0.5 wt %. The strength of the new PI films dried at 60° C. increased by 55% and 72% for 0.1 wt % MWCNT and 0.5 wt % MWCNT loadings, respectively, while the fracture resistance increased by 23% for the 0.1 wt % MWCNTs and then decreases at a loading of 0.5 wt % MWCNTs. The films can be advantageously be created by managing a corresponding shift in the annealing temperature at which the maximum strength occurs as the MWCNT loadings increase.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: May 19, 2015
    Assignee: Tuskegee University
    Inventor: Heshmat Aglan