Patents Assigned to Tutogen Medical GmbH
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Publication number: 20240115621Abstract: The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes.Type: ApplicationFiled: December 20, 2023Publication date: April 11, 2024Applicant: Tutogen Medical GmbHInventors: Arnd Wilhelmi, Silke Schreiner, Jake Michaelson, Steven Moore, Jennifer Faleris, Anne Reinlein
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Patent number: 11883437Abstract: The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes.Type: GrantFiled: June 10, 2022Date of Patent: January 30, 2024Assignee: Tutogen Medical GmbHInventors: Arnd Wilhelmi, Silke Schreiner, Jake Michaelson, Steven Moore, Jennifer Faleris, Anne Reinlein
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Patent number: 11382933Abstract: The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes.Type: GrantFiled: September 4, 2020Date of Patent: July 12, 2022Assignee: Tutogen Medical GmbHInventors: Arnd Wilhelmi, Silke Schreiner, Jake Michaelson, Steven Moore, Jennifer Faleris, Anne Reinlein
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Patent number: 10765703Abstract: The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes.Type: GrantFiled: August 27, 2018Date of Patent: September 8, 2020Assignee: TUTOGEN MEDICAL GMBHInventors: Arnd Wilhelmi, Silke Schreiner, Jake Michaelson, Steven Moore, Jennifer Faleris, Anne Reinlein
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Publication number: 20190111087Abstract: The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes.Type: ApplicationFiled: August 27, 2018Publication date: April 18, 2019Applicant: TUTOGEN MEDICAL GMBHInventors: Arnd Wilhelmi, Silke Schreiner, Jake Michaelson, Steven Moore, Jennifer Faleris, Anne Reinlein
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Patent number: 10076543Abstract: The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes.Type: GrantFiled: March 15, 2013Date of Patent: September 18, 2018Assignee: TUTOGEN MEDICAL GMBHInventors: Arnd Wilhelmi, Silke Schreiner, Jake Michaelson, Steven Moore, Jennifer Faleris, Anne Reinlein
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Patent number: 9814745Abstract: The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes.Type: GrantFiled: March 14, 2013Date of Patent: November 14, 2017Assignee: TUTOGEN MEDICAL GMBHInventors: Arnd Wilhelmi, Silke Schreiner, Jake Michaelson, Steven Moore, Jennifer Faleris
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Patent number: 8585760Abstract: The invention relates to a vertebral column implant for intercorporal fusion to the vertebral column. Said implant consists of a body produced from preserved bone material, whose size is adapted to the vertebral interstice between adjacent vertebrae that is formed once the vertebral interbody has been removed. The vertebral column implant exhibits an improved distribution of forces.Type: GrantFiled: April 2, 2003Date of Patent: November 19, 2013Assignee: Tutogen Medical GmbHInventors: Jürgen Henninger, Klaus Landis
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Publication number: 20130209572Abstract: The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes.Type: ApplicationFiled: March 15, 2013Publication date: August 15, 2013Applicant: Tutogen Medical GmbHInventor: Tutogen Medical GmbH
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Publication number: 20120167239Abstract: This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to a novel ecdysone receptor/invertebrate retinoid X receptor-based inducible gene expression system and methods of modulating gene expression in a host cell for applications such as gene therapy, large-scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.Type: ApplicationFiled: February 20, 2002Publication date: June 28, 2012Applicant: TUTOGEN MEDICAL GMBHInventors: Subba Reddy Palli, Marianna Z. Kapitskaya
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Publication number: 20110177591Abstract: A process and a device for preparing a dermis implant of a predefinable thickness provides for a section of skin (30) to be laid on a plate (20). Subcutaneous material is removed with a milling cutter (40) until the skin is of the desired thickness.Type: ApplicationFiled: May 21, 2008Publication date: July 21, 2011Applicant: TUTOGEN MEDICAL GMBHInventors: Peter Iwatschenko, Hans Gärtner, Arnd Wilhelmi
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Patent number: 7655615Abstract: The aim of the invention is to produce a bone material which is enriched with bone growth factors and whose bone growth factors are released in a delayed manner after surgically applied in the body. To this end, the invention provides a method according to which the bone material is loaded with a bone growth factor or with a mixture of bone growth factors and is then coated with a reabsorbable substance.Type: GrantFiled: December 5, 2000Date of Patent: February 2, 2010Assignee: Tutogen Medical GmbHInventor: Ludwig Baumgartner
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Patent number: 7060096Abstract: The invention relates to a vertebral column implant for intercorporal fusion on the vertebral column, consisting of a body which consists of bone material and which is curved in the direction in which it extends longitudinally. The size of the implant is adapted to the intermediate vertebral space available between adjacent vertebrae after the intermediate vertebral body has been removed.Type: GrantFiled: October 30, 2000Date of Patent: June 13, 2006Assignee: Tutogen Medical GmbHInventors: Christoph Schopf, Karl Koschatzky, Rolf-Dieter Kalas, Matthias Lowel
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Patent number: 7018413Abstract: The invention relates to a spinal implant consisting of a bone material body which is embodied in a curved manner in its longitudinal direction and is provided with coupling means.Type: GrantFiled: August 28, 2002Date of Patent: March 28, 2006Assignee: Tutogen Medical GmbHInventor: Manfred Krüger
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Patent number: 6988015Abstract: The inventive bone implant for replacing defective joint sockets comprises a base body (10) consisting of preserved natural spongiosa with an approximately hemispherical cavity (12).Type: GrantFiled: October 30, 2000Date of Patent: January 17, 2006Assignee: Tutogen Medical GmbHInventors: Christoph Schöpf, Karl Koschatzky, Rolf-Dieter Kalas, Matthias Löwel
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Patent number: 6942961Abstract: The invention relates to a two-step method for dehydrating biological tissues for producing preserved transplants. In a first step, the tissue is partially dehydrated with an organic, water-miscible solvent. In a second step, the tissue is dehydrated further by freeze drying.Type: GrantFiled: July 24, 2000Date of Patent: September 13, 2005Assignee: Tutogen Medical GmbHInventor: Ludwig Baumgartner
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Publication number: 20040034374Abstract: A hernia implant consists of a collagen membrane which is gained from biological starting material and is provided with a plurality of drainage openings.Type: ApplicationFiled: April 17, 2003Publication date: February 19, 2004Applicant: Tutogen Medical GmbHInventors: Steffen Zatzsch, Christoph Schopf
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Patent number: 6379385Abstract: A spinal column implant consists of a base body of spongeous bone matter into which at least one load-carrying support element is embedded.Type: GrantFiled: January 6, 2000Date of Patent: April 30, 2002Assignee: Tutogen Medical GmbHInventors: Rolf-Dieter Kalas, Karl Koschatzky, Manfred Krüger, Christoph Schöpf