Patents Assigned to Tvardi Therapeutics, Inc.
  • Therapeutic compounds, formulations, and uses thereof
    Patent number: 11547683
    Abstract: Provided herein are compositions, formulations, and (e.g., oral) dosage forms comprising a compound of Formula (I). In specific instances, such compositions comprise an emulsifier, a solubilizer, a polyethylene glycol, a surfactant, and an antioxidant. In some instances, such compositions are useful for the treatment of fibrosis, cancer, and/or chronic inflammation.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: January 10, 2023
    Assignee: Tvardi Therapeutics, Inc.
    Inventors: Imran Alibhai, Sofia De Achaval, Beverly C. Langevin, Tian Zhou
  • Therapeutic compounds, formulations, and uses thereof
    Patent number: 11077077
    Abstract: Provided herein are compositions, formulations, and (e.g., oral) dosage forms comprising a compound of Formula (I). In specific instances, such compositions comprise an emulsifier, a solubilizer, a polyethylene glycol, a surfactant, and an antioxidant. In some instances, such compositions are useful for the treatment of fibrosis, cancer, and/or chronic inflammation.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: August 3, 2021
    Assignee: Tvardi Therapeutics, Inc.
    Inventors: Imran Alibhai, Sofia De Achaval, Beverly C. Langevin, Tian Zhou
  • STAT3 inhibitors
    Patent number: 11026905
    Abstract: Compounds as STAT3 inhibitors are described. A pharmaceutical composition comprising the same, methods of making the same, and a method for treating or preventing conditions such as cancer, chronic inflammation, and fibrosis using the same, are described.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: June 8, 2021
    Assignees: Tvardi Therapeutics, Inc., Baylor College of Medicine
    Inventors: Sofia De Achaval, David John Tweardy