Abstract: A contact lens system includes a shared antenna electrode, an accommodation actuator to provide variable optical power, and a controller coupled to the accommodation actuator and the shared antenna electrode. The controller including logic for arbitrating access to the shared antenna electrode between an impedance sensor and a communication circuit; selectively establishing an oscillator with the impedance sensor and the shared antenna electrode; correlating an oscillation condition of the oscillator to an accommodation setting; and adjusting the variable optical power of the accommodation actuator based upon the accommodation setting. An impedance across the shared antenna electrode varies based upon an amount an eyelid overlaps the contact lens system when the contact lens system is worn on an eye.

Abstract: An eye-mountable device is provided that includes a plurality of rigid polymer layers separated by liquid crystal layers. Certain eye-mountable devices includes a first rigid polymer layer, a second rigid polymer layer, and a liquid crystal layer between the first and second rigid polymer layers. The liquid crystal layer has a refractive index that is electrically controllable between an ordinary refractive index and an extraordinary refractive index, and the first rigid polymer layer and second rigid polymer layer include materials having a refractive index similar to the ordinary refractive index of the liquid crystal layer. The first rigid polymer layer and second rigid polymer layer may also include a combination of monomer-derived units that provide cast-moldable materials with high oxygen permeability. Methods for fabricating the eye-mountable device and for changing the focal length of the eye-mountable device are also provided.

Abstract: Disclosed is a headset for monitoring periocular humidity, the headset including a housing configured to be positioned on a user's face and defining a periocular air space. The headset includes a humidity sensor configured to measure a humidity of air within the periocular air space, and an ophthalmic testing unit configured to measure a physiological parameter of an eye of the user. The headset further includes a processor coupled to the humidity sensor and the ophthalmic testing unit. The processor is configured to receive the measured humidity and the measured physiological parameter, and determine an ophthalmic condition based on the measured humidity and the measured physiological parameter.

Abstract: An intraocular micro-display (IOMD) system includes an auxiliary head unit. The auxiliary head unit includes a frame for mounting to a head of a user, a scene camera module mounted in or on the frame in a forward-facing orientation, a gaze tracking module disposed in or on the frame and configured to monitor an eye of the user, and an auxiliary controller. The auxiliary controller includes for: acquiring a scene image with the scene camera module, determining a gazing direction of the eye based upon gaze direction data from the gaze tracking module, identifying a sub-portion of the scene image based upon the gazing direction, and wirelessly relaying the sub-portion of the scene image to an IOMD implant within the eye for displaying to a retina of the eye.

Abstract: Systems, devices and methods that facilitate safe heating of eyelids to treat dry eye are disclosed. According to one embodiment, an apparatus for optical heating of an eyelid of a patient includes: a housing configured to be grasped by a human hand; at least one light emitter coupled to the housing and configured to emit beams of infrared light; a waveguide component coupled to the at least one light emitter and configured to direct the beams of light toward the eyelid; and a scleral cover configured to couple to the housing, the scleral cover comprising: a curved protective portion configured to reflect infrared light emanating from the at least one light emitter.

Abstract: A device is presented herein that is configured to be located underneath an eyelid and worn by a user for treating dry eye. The device includes a first surface configured to face a portion of a sclera of the eye, and a second surface configured to face an eyelid and to be completely covered by the eyelid. In some embodiments, the device further includes a plurality of stimulation electrodes proximal to the first surface, wherein the plurality of stimulation electrodes is configured to stimulate the sclera. The device further includes an energy storage element coupled to the plurality of stimulation electrodes. The energy storage element is configured to supply power to the plurality of stimulation electrodes. The device further includes a processor configured to control a supply of energy from the energy storage element to the plurality of stimulation electrodes to stimulate the sclera.

Abstract: An ophthalmic device includes a housing configured to hold an injectant chamber configured to store an injectant, a plunger disposed within the injectant chamber, and a stopper coupled to a distal portion of the plunger. The device also includes a hypodermic needle disposed at a distal end of the housing, and a sample chamber located within the housing adjacent to the distal end. The housing, hypodermic needle, and sample chamber are arranged such that when the stopper is moved to a first depth within the housing, the sample chamber is configured to receive material via the hypodermic needle. The housing, hypodermic needle, and sample chamber are also arranged such that when the stopper is moved to a second depth within the housing exceeding the first depth, the injectant chamber is configured to dispense the injectant through the hypodermic needle.

Abstract: An ophthalmic device comprises an ultrasonic transducer, an accommodation actuator, and a controller. When the ophthalmic device is mounted in or on an eye of a user, the ultrasonic transducer is positioned to direct ultrasonic signals towards ciliary processes in the eye and the accommodation actuator is positioned to focus light entering the eye. The controller is coupled to the ultrasonic transducer and the accommodation actuator. The controller includes logic that when executed by the controller causes the ophthalmic device to perform operations including emitting the ultrasonic signals from the ultrasonic transducer towards the ciliary processes, receiving reflected ultrasonic signals from the ciliary processes with the ultrasonic transducer, calculating a time of flight between emitting the ultrasonic signals and receiving the reflected ultrasonic signals, and adjusting an optical power of the accommodation actuator based on the time of flight.

Abstract: A fluid dispensing device includes a cartridge comprising a housing and a head coupled to the housing. The housing forms a first chamber configured to accommodate a fluid; and the head includes a nozzle; and an elastomeric wall that is spaced from the nozzle to form a holding chamber. The holding chamber is in fluid communication with the first chamber and configured to accommodate a portion of the fluid; and the nozzle forms one or more openings to eject the portion of the fluid from the holding chamber. The one or more openings form an oblong shape such that a length of the oblong shape is greater than a width of the oblong shape. The one or more openings can include two parallel slots that together form the oblong shape.

Abstract: A fluid dispensing device includes a light source, and a nozzle spaced from the light source. The device also includes a membrane positioned within a beam path of the light source, where the membrane is configured to allow a portion of light from the light source through to the nozzle. The device also includes a fluid chamber positioned between the membrane and the nozzle, where the nozzle is configured to allow a beam of the portion of light to pass through along the beam path, and where the nozzle is further configured to form a stream of fluid expelled from the fluid chamber along the beam path.

Abstract: Systems, eye-mountable devices, and methods that facilitate chronotherapeutic treatment of primary open-angle glaucoma are provided which enable therapeutic products to be delivered to the eye in a controlled manner only when desired. According to one embodiment, an eye-mountable device comprises a substrate having an eye-mounting surface for positioning on an eye of a patient, a sensor that obtains a plurality of measurements representative of a condition of the eye of the patient over a period of time, a therapeutic agent delivery assembly coupled, and a processor for executing a temporal model of a therapeutic agent delivery in communication with the sensor and the therapeutic agent delivery assembly. The processor receives the plurality of measurements and activates the therapeutic agent delivery assembly to administer a first amount of a drug to the eye of the patient based on the temporal model associated with the plurality of measurements.

Abstract: Pumps for noncontact tonometry are provided. In one embodiment, a pump for noncontact tonometry includes a compression pump, a compression chamber, a first pressure sensor in communication with the compression chamber, a surge chamber, and a valve separating the compression chamber and surge chamber. The compression pump compresses a first volume of gas into the compression chamber. When the first pressure sensor detects a threshold pressure in the compression chamber, the valve opens and releases the gas into a surge chamber, where it combines with a gas residing in the surge chamber to form a puff of gas that escapes from the surge chamber through a flow-limiting nozzle. The components of the pump, which relies on passive rather than active components to create the controlled puff, can be assembled to have a profile that is portable and fit for home use.

Abstract: An intraocular pressure (IOP) measurement system. An optical pressure sensor is implantable in the cornea of an eye, wherein the sensor has a sealed cavity that changes shape as a function of IOP of the eye. An optical transmitter that is outside of the eye emits an incident optical beam. A receiver that is also outside of the eye produces an output signal in response to receiving reflections of the incident beam from the sensor. A processor is configured to estimate the IOP of the eye based on processing the output signal of the receiver. Other aspects are also described and claimed.

Abstract: A fluid dispensing device includes a cartridge comprising a housing and a head coupled to the housing. The housing forms a first chamber configured to accommodate a fluid; and the head includes a nozzle; and an elastomeric wall that is spaced from the nozzle to form a holding chamber. The holding chamber is in fluid communication with the first chamber and configured to accommodate a portion of the fluid; and the nozzle forms one or more openings to eject the portion of the fluid from the holding chamber. The one or more openings form an oblong shape such that a length of the oblong shape is greater than a width of the oblong shape. The one or more openings can include two parallel slots that together form the oblong shape.

Abstract: The present disclosure relates to relates to systems and methods for on-demand delivery of a therapeutic agent from an eye mounted device. Particularly, aspects of the present invention are directed to a method of delivering a therapeutic agent, the method including receiving, at a controller of a therapeutic agent release and delivery device, a first command signal for delivery of a therapeutic agent based on a dosing time window. Upon receipt of the first command signal, the controller determines whether one or more compliance conditions are satisfied. When the one or more conditions are satisfied, the controller initiate a release and delivery protocol that commands a signal generator to generate and send a second command signal causing a capacitor or one or more circuits to deliver an actuation signal causing one or more therapeutic agent delivery mechanisms to open and release the therapeutic agent from one or more reservoirs.

Abstract: According to some aspects, a device is presented herein that is configured to be located underneath an eyelid and worn by a user for treating dry eye. The device includes a first surface configured to face a portion of a sclera of the eye, and a second surface configured to face an eyelid and to be completely covered by the eyelid. In some embodiments, the device further includes a plurality of stimulation electrodes proximal to the first surface, wherein the plurality of stimulation electrodes is configured to stimulate the sclera. The device further includes an energy storage element coupled to the plurality of stimulation electrodes. The energy storage element is configured to supply power to the plurality of stimulation electrodes. The device further includes a processor configured to control a supply of energy from the energy storage element to the plurality of stimulation electrodes to stimulate the sclera.

Abstract: The present disclosure relates to devices and systems for targeted and controlled delivery of a therapeutic agent to a treatment site of an eye. Particularly, aspects are directed to a therapeutic agent delivery device that includes a polymeric substrate having a release region, a delivery region, and a receiving region; one or more reservoirs formed within the release region; a therapeutic agent disposed within the one or more reservoirs; an active, passive, or combination thereof controlled release mechanism for release of the therapeutic agent from the one or more reservoirs into the delivery region; and a circuit formed on the polymeric substrate, the circuit having a current source, a first iontophoresis electrode located within the delivery region for transport of the therapeutic agent from the delivery region into a target tissue via electromigration, and a second iontophoresis electrode located within the receiving region for maintaining electroneutrality within the tissue.

Abstract: A periocular ring configured to be worn on an eye of a user that includes a plurality of electrodes spaced along the periocular ring; a microcontroller; and a lead assembly extending along at least a portion of the periocular ring; wherein the lead assembly extends between the microcontroller and the plurality of electrodes to operably couple the plurality of electrodes to the microcontroller; and wherein the microcontroller is configured to activate the plurality of electrodes via the lead assembly to stimulate a lacrimal gland of the user. The periocular ring has an opening that defines an innermost diameter; and wherein, when the periocular ring is worn on the eye of the user, a portion of the eye extends through the opening of the periocular ring.

Abstract: A periocular assembly that is configured to be positioned in the fornix of an eye of the user includes a ring; a plurality of electrodes spaced along the ring; a microcontroller operably coupled to the plurality of electrodes; and a sensor assembly coupled to the ring and operably coupled to the microcontroller. A method of stimulating a lacrimal gland of the user includes monitoring eye condition(s) using the sensor assembly; determining, based on the monitored eye condition(s) and using the microcontroller, if the monitored eye conditions(s) exceed a predetermined threshold; and activating, using the microcontroller and in response to the monitored eye condition(s) exceeding the predetermined threshold, the plurality of electrodes to stimulate the lacrimal gland of the user.

Abstract: Systems and methods for determining the identity of a liquid within a liquid dispenser are provided. A device includes a holder having an opening that is configured to retain the liquid dispenser. A surface of the liquid dispenser is configured to affix a label identifying a liquid within the liquid dispenser. A plurality of lenses are mounted on the holder. Each lens has a respective field of view that includes a respective portion of the surface of the liquid dispenser. In addition, the device includes a plurality of fiber bundles. Each fiber bundle includes an input that is configured to receive a respective signal from a respective one of the plurality of lenses. Further, the device includes an imaging sensor that is configured to receive the respective signals from the plurality of fiber bundles and to form a plurality of images of the surface of the liquid dispenser.