Patents Assigned to TWi Biotechnology, Inc.
  • Methods and pharmaceutical compositions for preventing or treating immunoinflammatory dermal disorders
    Patent number: 10675260
    Abstract: A method for preventing or treating immunoinflammatory dermal disorders is provided. Also provided is a pharmaceutical composition for preventing or treating immunoinflammatory dermal disorders.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: June 9, 2020
    Assignee: TWi Biotechnology, Inc.
    Inventors: Po-Yuan Tseng, Wei-Shu Lu, Carl Oscar Brown, III, I-Yin Lin, III, Chen-En Tsai, Chih-Kuang Chen
  • Therapeutic uses of berberine formulations
    Patent number: 10213418
    Abstract: Uses of pharmaceutical compositions comprising berberine for treatment of dermatologic toxicities and other skin disorders.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: February 26, 2019
    Assignee: TWi Biotechnology, Inc.
    Inventors: Po-Yuan Tseng, Carol Oscar Brown, III, I-Yin Lin, Chen-En Tsai, Chih-Kuang Chen
  • Methods for inhibiting expression of ASC, expression of NLRP3, and/or formation of NLRP3 inflammasome complex using diacerein or its analogs
    Patent number: 10195170
    Abstract: Methods and compositions for inhibiting expression of ASC, expression of NLRP3, and/or formation of NLRP3 inflammasome complex by using diacerein or its analogs are provided. Also provided are methods and compositions for the treatment and/or prevention of a disorder mediated by ASC and/or NLRP3, and/or by formation of NLRP3 inflammasome complex by using diacerein or its analogs.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: February 5, 2019
    Assignee: TWI Biotechnology, Inc.
    Inventors: Chih-Kuang Chen, Jing-Yi Lee, Wei-Shu Lu, Carl Oscar Brown, III
  • Diacerein or Rhein topical formulations and uses thereof
    Patent number: 10154984
    Abstract: A topical pharmaceutical composition containing diacerein and/or its analogs is provided. Also provided is a method for treating various diseases using this topical pharmaceutical composition.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: December 18, 2018
    Assignee: TWi Biotechnology, Inc.
    Inventors: Chih-Kuang Chen, Jing-Yi Lee, Wei-Shu Lu, Carl Oscar Brown, III
  • Diacerein or rhein topical formulations and uses thereof
    Patent number: 9744131
    Abstract: A topical pharmaceutical composition containing diacerein and/or its analogs is provided. Also provided is a method for treating various diseases using this topical pharmaceutical composition.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: August 29, 2017
    Assignee: TWi Biotechnology, Inc.
    Inventors: Chih-Kuang Chen, Jing-Yi Lee, Wei-Shu Lu, Carl Oscar Brown, III
  • Berberine formulations and uses thereof
    Patent number: 9427432
    Abstract: Pharmaceutical compositions comprising berberine for treatment of skin disorders and methods of use thereof.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: August 30, 2016
    Assignee: TWi Biotechnology, Inc.
    Inventors: Pao-Li Wang, Way-Yu Lin, Chen-Mao Lin, Po-Yuan Tseng
  • Methods and compositions for treating hyperuricemia and metabolic disorders associated with hyperuricemia
    Patent number: 8865689
    Abstract: Methods and compositions for treating and/or preventing hyperuricemia or metabolic disorders associated with hyperuricemia comprising administering to a patient in need a therapeutically effective amount of diacerein, rhein, or a pharmaceutically acceptable salt, an analog, a prodrug, or an active metabolite thereof.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: October 21, 2014
    Assignee: TWi Biotechnology, Inc.
    Inventors: Mannching Sherry Ku, Chih-Kuang Chen, Wei-Shu Lu, I-Yin Lin
  • Methods of decreasing glycosylated hemoglobin in patients with dyslipidemia
    Patent number: 8846758
    Abstract: Methods for treating abnormal glycosylated hemoglobin (HbA1c) levels in a patient in need thereof, wherein the provided methods comprise administering to a patient in need a therapeutically effective amount of an Interleukin-1? modulator. Also, the invention provides compositions comprising at least one lipid modifying agent and an IL-1? modulator.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: September 30, 2014
    Assignee: TWi Biotechnology, Inc.
    Inventors: Mannching Sherry Ku, Chih-Kuang Chen, Wei-Shu Lu, Chih-Ming Chen, I-Yin Lin
  • Methods of using diacerein as an adjunctive therapy for diabetes
    Patent number: 8536152
    Abstract: The present invention provides methods of treating type II diabetes using combinations of diacerein or its derivatives with other antidiabetic agents. The methods may also allow improving glycemic control of type II diabetes patients and/or reducing side effects and/or cardiovascular risks of antidiabetic agents.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: September 17, 2013
    Assignee: TWi Biotechnology, Inc.
    Inventors: Mannching Sherry Ku, Danchen Gao, Wei-Shu Lu, Chih-Ming Chen, I-Yin Lin
  • METHODS AND COMPOSITIONS FOR TREATING HYPERURICEMIA AND METABOLIC DISORDERS ASSOCIATED WITH HYPERURICEMIA
    Publication number: 20120232044
    Abstract: Methods and compositions for treating and/or preventing hyperuricemia or metabolic disorders associated with hyperuricemia comprising administering to a patient in need a therapeutically effective amount of diacerein, rhein, or a pharmaceutically acceptable salt, an analog, a prodrug, or an active metabolite thereof.
    Type: Application
    Filed: March 7, 2012
    Publication date: September 13, 2012
    Applicant: TWi Biotechnology, Inc.
    Inventors: Mannching Sherry Ku, Chih-Kuang Chen, Wei-Shu Lu, I-Yin Lin