Abstract: The invention provides methods for attaching drugs, dyes or radiolabels to bis-MTX. This method can be used to prepare bis-MTX analogs that can be used to deliver agents, such as nanoparticles, drugs, dyes or radiolabels, to cells.
Type:
Grant
Filed:
January 18, 2013
Date of Patent:
November 8, 2016
Assignee:
TYCHON BIOSCIENCE, LLC
Inventors:
Carston R. Wagner, Jae Chul Lee, Sidath C. Kumarapperuma