Patents Assigned to TYRX, Inc.
  • LINEAR POLYESTERAMIDES FROM AMINOPHENOLIC ESTERS
    Publication number: 20130157930
    Abstract: The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.
    Type: Application
    Filed: February 13, 2013
    Publication date: June 20, 2013
    Applicant: TYRX, INC.
    Inventor: TYRX, INC.
  • Linear polyesteramides from aminophenolic esters
    Patent number: 8445603
    Abstract: The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: May 21, 2013
    Assignee: TYRX, Inc.
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula, Archana Rajaram, Arikha Moses
  • Preventing biofilm formation on implantable medical devices
    Patent number: 8315700
    Abstract: Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device and preventing or retarding the formation of a biofilm.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: November 20, 2012
    Assignee: TYRX, Inc.
    Inventors: Mark Citron, William McJames
  • ANCHORAGE DEVICES COMPRISING AN ACTIVE PHARMACEUTICAL INGREDIENT
    Publication number: 20120185004
    Abstract: An anchorage device comprising a mesh substrate coupled to an implantable medical device is disclosed, where the mesh substrate has a coating comprising a polymer, and the mesh further comprises at least one active pharmaceutical ingredient. The active pharmaceutical agent is designed to elute from the mesh over time. The mesh substrate can be configured to reduce the mass of the anchorage device such that tissue in-growth and/or scar tissue formation at the treatment site is reduced. In some embodiments, the mesh substrate can be formed with a mesh having a low areal density. In some embodiments, the mesh substrate can include one or more apertures or pores to reduce the mass of the substrate.
    Type: Application
    Filed: November 10, 2011
    Publication date: July 19, 2012
    Applicant: TYRX, Inc.
    Inventors: William McJames, Frank Do, Satish Pulapura, Qing Ge
  • RESORBABLE PHENOLIC POLYMERS
    Publication number: 20120165495
    Abstract: The invention provides biocompatible resorbable polymers, comprising monomer units having formula (I), formula (II), formula (III) or formula (IV). The polymers degrade over time when implanted in the body, and are useful as components of implantable medical devices.
    Type: Application
    Filed: March 7, 2012
    Publication date: June 28, 2012
    Applicant: TYRX, Inc.
    Inventors: Arikha Moses, Satish Pulapura, Arthur Schwartz, Qing Ge, Irene Shatova
  • Resorbable phenolic polymers
    Patent number: 8153837
    Abstract: The invention provides biocompatible resorbable polymers, comprising monomer units having formula (I), formula (II), formula (III) or formula (IV). The polymers degrade over time when implanted in the body, and are useful as components of implantable medical devices.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: April 10, 2012
    Assignee: TYRX, Inc.
    Inventors: Arikha Moses, Satish Pulapura, Arthur Schwartz, Qing Ge, Irene Shatova