Patents Assigned to U.S. Dept. of Health and Human Services, National Institutes of Health
  • AAV4 vector and uses thereof
    Patent number: 8507267
    Abstract: The present invention provides an adeno-associated virus 4 (AAV4) virus and vectors and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid to a cell using the AAV4 vectors and particles.
    Type: Grant
    Filed: March 8, 2010
    Date of Patent: August 13, 2013
    Assignee: U.S. Dept. of Health and Human Services, National Institutes of Health
    Inventors: John A. Chiorini, Robert M. Kotin, Nancy Safer
  • Mammalian sweet taste receptors
    Publication number: 20050260599
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
    Type: Application
    Filed: August 20, 2003
    Publication date: November 24, 2005
    Applicants: The Regents of the University of California, The Govt. of the U.S.A., Dept. of Health and Human Services National Institutes of Health-OTT
    Inventors: Nicholas Ryba, Mark Hoon, Charles Zuker, Gregory Nelson, Jayaram Chandrashekar, Yifeng Zhang