Abstract: A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of joint pain. The composition includes pro-inflammatory low molecular weight microbial fermented sodium hyaluronate fragments having a molecular weight of 0.5 to 300 kilodaltons (kDa) in an oral dosage form.
Type:
Grant
Filed:
May 3, 2018
Date of Patent:
April 21, 2020
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of hot flashes in a female subject, such as experiencing symptoms of perimenopause. The composition includes a phytoestrogen and lycopene in an oral dosage form. The phytoestrogen may include a plant lignan including at least one of Matairesinol, 7-hydroxymatairesinol, Secoisolariciresinol, Lariciresinol and Pinoresinol. The lycopene may include a lycopene complex having at least one of phytoene, phytofluene, beta-carotene, tocopherols and phytosterols.
Type:
Grant
Filed:
May 1, 2017
Date of Patent:
January 8, 2019
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, Jessica Engle
Abstract: A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of joint pain. The composition includes pro-inflammatory low molecular weight microbial fermented sodium hyaluronate fragments having a molecular weight of 0.5 to 300 kilodaltons (kDa) in an oral dosage form.
Type:
Grant
Filed:
June 28, 2016
Date of Patent:
June 19, 2018
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A dietary supplement composition and associated method of use has the composition formulated in a therapeutic amount to treat and alleviate symptoms of joint pain in a person having joint pain. The composition includes astaxanthin and microbial fermented, low molecular weight hyaluronic acid or sodium hyaluronate (hyaluronan). The composition also includes at least one of a phospholipid, glycolipid, and sphingolipid. It is formulated into an oral dosage form and the astaxanthin is 0.1 to 15 percent by weight of the at least one phospholipid, glycolipid, and sphingolipid.
Type:
Grant
Filed:
September 21, 2016
Date of Patent:
May 22, 2018
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A dietary supplement composition and associated method of use has the composition formulated in a therapeutic amount to treat and alleviate symptoms of joint pain in a person having joint pain. The composition includes astaxanthin and microbial fermented, low molecular weight hyaluronic acid or sodium hyaluronate (hyaluronan). The composition also includes at least one of a phospholipid, glycolipid, and sphingolipid. It is formulated into an oral dosage form and the astaxanthin is 0.1 to 15 percent by weight of the at least one phospholipid, glycolipid, and sphingolipid.
Type:
Grant
Filed:
March 12, 2015
Date of Patent:
March 13, 2018
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of joint pain. The composition includes pro-inflammatory low molecular weight microbial fermented sodium hyaluronate fragments having a molecular weight of 0.5 to 300 kilodaltons (kDa) and astaxanthin in an oral dosage form. The astaxanthin may be derived from a natural or synthetic ester or synthetic diol. The composition may include a mixture of cartilage and salt and boron.
Type:
Grant
Filed:
June 27, 2016
Date of Patent:
October 24, 2017
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A composition of matter comprises a shelf stable, partially defatted supercritical CO2 fluid solvent extracted whole grain flour derived from a cracked biomass of perilla frutescens, the flour comprising minerals and 2 to 8 percent of native seed oil, 35 to 45 percent protein, and 35 to 45 percent fiber.
Type:
Grant
Filed:
June 5, 2013
Date of Patent:
September 26, 2017
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, Uy Nguyen
Abstract: A dietary supplement includes comprising a therapeutic amount of astaxanthin derived from a synthetic or natural ester or diol, and at least one of a phospholipid, glycolipid, and sphingolipid, and formulated into an oral dosage form, wherein the astaxanthin is 0.1 to 15 percent by weight of the at least one phospholipid, glycolipid, and sphingolipid. The composition includes 0.5 to 12 mg of astaxanthin and may be used to treat low density lipoprotein (LDL) oxidation in humans and other diseases, disorders and impairments.
Type:
Grant
Filed:
March 16, 2015
Date of Patent:
September 19, 2017
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of joint pain. The composition includes pro-inflammatory low molecular weight microbial fermented sodium hyaluronate fragments and glucosamine in an oral dosage form.
Type:
Grant
Filed:
June 10, 2015
Date of Patent:
June 13, 2017
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of hot flashes in a female subject, such as experiencing symptoms of perimenopause. The composition includes a phytoestrogen and lycopene in an oral dosage form. The phytoestrogen may include a plant lignan including at least one of Matairesinol, 7-hydroxymatairesinol, Secoisolariciresinol, Lariciresinol and Pinoresinol. The lycopene may include a lycopene complex having at least one of phytoene, phytofluene, beta-carotene, tocopherols and phytosterols.
Type:
Grant
Filed:
July 28, 2015
Date of Patent:
June 6, 2017
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, Jessica Engle
Abstract: A dietary supplement composition is formulated in a therapeutically effective amount to treat the eye of an individual. The composition includes a perilla seed oil extract, astaxanthin, and at least one carotenoid selected from the group consisting of lutein, trans-zeaxanthin and meso-zeaxanthin.
Type:
Grant
Filed:
May 13, 2014
Date of Patent:
April 4, 2017
Assignee:
U.S. NUTRACEUTICALS
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, Uy Nguyen
Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA either alone or in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.
Type:
Grant
Filed:
April 30, 2015
Date of Patent:
March 21, 2017
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA either alone or in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.
Type:
Grant
Filed:
July 8, 2015
Date of Patent:
March 21, 2017
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A medicine delivery system delivers medicine such as a dietary supplement to improve prostate health and includes an outer capsule containing a saw palmetto extract and an inner capsule within the outer capsule and containing a carotenoid. The outer capsule is formed to dissolve in the stomach when ingested to release the saw palmetto extract into the stomach and the inner capsule is formed to pass into the duodenum to dissolve and release the carotenoid into the duodenum.
Type:
Grant
Filed:
March 27, 2014
Date of Patent:
March 14, 2017
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A Salvia hispanica L. derived seed oil extract composition of matter containing from 60-88% PUFAs in a ratio of from 3.1:1-3.3:1 of ALA to LA, 4-10% of C-18 mono-unsaturated fatty acid, 1-5% of C-18 saturated fatty acid and 4-8% of C-16 saturated fatty acid in a mixed triglyceride form stable at room temperature of 12-24 months containing a mixture of selected antioxidants.
Type:
Grant
Filed:
September 27, 2013
Date of Patent:
January 3, 2017
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, Uy Nguyen
Abstract: A composition of matter comprises a shelf stable, super critical, CO2 fluid extracted seed oil derived from a cracked biomass of perilla frutescens, the seed oil comprising from about 60 to about 95 percent w/w of PUFAs in a ratio of from about 4:1 to about 6:1 alpha-linolenic acid (ALA) to linoleic acid (LA) and a mixture of selected antioxidants.
Type:
Grant
Filed:
June 11, 2014
Date of Patent:
December 6, 2016
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, Uy Nguyen
Abstract: A composition of matter comprises a shelf stable, partially defatted supercritical CO2 fluid solvent extracted whole grain flour derived from a cracked biomass of perilla frutescens, the flour comprising minerals and 2 to 8 percent of native seed oil, 35 to 45 percent protein, and 35 to 45 percent fiber.
Type:
Grant
Filed:
February 6, 2014
Date of Patent:
August 16, 2016
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, Uy Nguyen
Abstract: A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of joint pain. The composition includes pro-inflammatory low molecular weight microbial fermented sodium hyaluronate fragments having a molecular weight of 0.5 to 300 kilodaltons (kDa) and astaxanthin in an oral dosage form. The astaxanthin may be derived from a natural or synthetic ester or synthetic diol. The composition may include a mixture of cartilage and salt and boron.
Type:
Grant
Filed:
March 12, 2015
Date of Patent:
August 2, 2016
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A dietary supplement composition and associated method has its composition formulated in a therapeutic amount to treat and alleviate symptoms of joint pain in a person having joint pain. The composition includes astaxanthin, low molecular weight hyaluronic acid or sodium hyaluronate (hyaluronan) having a molecular weight of 0.5 to 300 kilodaltons (kDa), and a phospholipid rich egg roe extract having phospholipid bound EPA and DHA admixed with seed and/or fish oil having an ALA to LA ratio of 1:1 to 6:1 and in an oral dosage form.
Type:
Grant
Filed:
March 12, 2015
Date of Patent:
July 26, 2016
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
Abstract: A method of enhancing cardiovascular health includes administering a therapeutic amount of a composition comprising krill oil reacted with astaxanthin. A medicine delivery system for the method and composition includes an inner capsule containing carotenoids and an outer capsule in which the inner capsule is contained within the outer capsule and the outer capsule containing a therapeutically effective amount of krill oil. In one example, the carotenoids comprise at least S,S?-astaxanthin derived from Haematococcus pluvialis.
Type:
Grant
Filed:
June 17, 2014
Date of Patent:
May 31, 2016
Assignee:
U.S. NUTRACEUTICALS, LLC
Inventors:
John A. Minatelli, W. Stephen Hill, Rudi E. Moerck