Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
Type:
Grant
Filed:
January 4, 2005
Date of Patent:
May 15, 2007
Assignee:
UCB Farchim S.A.
Inventors:
John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
Abstract: The present invention concerns a tablet comprising two distinct segments. More particularly the invention relates to combinations of two pharmaceutical substances and methods of treatment of allergic disorders.
Type:
Application
Filed:
November 12, 2003
Publication date:
June 8, 2006
Applicant:
UCB Farchim S.A.
Inventors:
Monique Berwaer, Anthony Guichaux, Serge Cuypers, Michel Deleers, Domenico Fanara
Abstract: In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment aid/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula Y-J-EAn? (I), wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).
Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
Type:
Grant
Filed:
July 1, 2003
Date of Patent:
February 22, 2005
Assignee:
UCB Farchim S.A.
Inventors:
John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing &agr;-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-&agr;-ethyl-2-oxo-1-pyrrolidine acetamide.
Type:
Grant
Filed:
August 20, 2002
Date of Patent:
March 30, 2004
Assignee:
UCB Farchim S.A.
Inventors:
John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann