Patents Assigned to UEA Enterprises Limited
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Patent number: 11958927Abstract: Described herein are methods of stereolithographically printing intraocular devices, in particular intraocular lenses, as well as stereolithographic compositions for use therein. The stereolithography composition may comprise: a photoinitiator; a monofunctional aryl acrylate monomer, wherein the acrylate group of the monofunctional aryl acrylate monomer is of the formula -0-(C?0)-CH?CH2; and a multifunctional methacrylate or acrylate cross-linker, wherein the monofunctional aryl acrylate monomer is present in the composition in a greater amount than the multifunctional methacrylate or acrylate cross-linker.Type: GrantFiled: September 5, 2019Date of Patent: April 16, 2024Assignee: UEA Enterprises, LimitedInventors: Aram Saeed, Michael Wormstone
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Patent number: 11946037Abstract: Provided are methods, compositions and kits for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host.Type: GrantFiled: November 24, 2020Date of Patent: April 2, 2024Assignee: UEA Enterprises LimitedInventors: Justin Joseph O'Grady, Gemma Louise Kay, Themoula Charalampous, Alp Aydin, Riccardo Scotti
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Patent number: 11505793Abstract: Provided is a method for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host, said method comprising the steps of (a) adding a cytolysin, or an active variant thereof, to said sample; and (b) carrying-out a process to physically deplete nucleic acid released from host cells within said sample or otherwise render such nucleic acid unidentifiable.Type: GrantFiled: December 12, 2017Date of Patent: November 22, 2022Assignee: UEA ENTERPRISES LIMITEDInventors: Justin Joseph O'Grady, John Richard Wain, Solomon Mwaigwisya, Gemma Louise Kay
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Publication number: 20210268094Abstract: This invention relates to the delivery of heterologous peptides or proteins such as therapeutic peptides, therapeutic proteins or antigens to mucosal sites using vesicles derived from the outer membrane of commensal bacteria, recombinant bacteria capable of producing such vesicles, and methods for the production of such vesicles. The invention further relates to an inducible expression system for use in recombinant bacteria.Type: ApplicationFiled: May 10, 2021Publication date: September 2, 2021Applicants: QUADRAM INSTITUTE BIOSCIENCE, UEA ENTERPRISES LIMITEDInventors: REGIS GABRIEL STENTZ, SIMON RICHARD CARDING
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Publication number: 20210254135Abstract: The present invention provides a method for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host and having been subjected to treatment to lyse host cells present in the sample, and having been subjected to a treatment to deplete nucleic acid released from host cells within said sample or otherwise to render such nucleic acid unidentifiable, the method comprising: (a) depleting host mitochondria or host mitochondrial DNA (mtDNA) present in the treated sample; and (b) extracting and/or analysing remaining nucleic acid from the treated sample. Also provided is a related kit comprising reagents for performing the method. Further claimed is a method for isolating mitochondrial DNA after host cells have been lysed and host cell nucleic acids have been removed from the sample.Type: ApplicationFiled: June 20, 2019Publication date: August 19, 2021Applicants: PROGENIKA BIOPHARMA, S.A., UEA ENTERPRISES LIMITEDInventors: Lourdes Palacios, Nerea Bartolome, Antonio Martinez, Justin Joseph O'Grady, Gemma Louise Kay
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Patent number: 11000581Abstract: This invention relates to the delivery of heterologous peptides or proteins such as therapeutic peptides, therapeutic proteins or antigens to mucosal sites using vesicles derived from the outer membrane of commensal bacteria, recombinant bacteria capable of producing such vesicles, and methods for the production of such vesicles. The invention further relates to an inducible expression system for use in recombinant bacteria.Type: GrantFiled: April 28, 2017Date of Patent: May 11, 2021Assignees: QUADRAM INSTITUTE BIOSCIENCE, UEA ENTERPRISES LIMITEDInventors: Regis Gabriel Stentz, Simon Richard Carding
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Patent number: 10700295Abstract: The present invention provides complexes of the formula (L)M(X), in which M is a metal atom selected from copper, silver and gold; L is a carbene ligand; and X is a monoanionic ligand. The complexes are useful as light emitters in the emissive zone of light-emitting devices such as OLEDs. The present invention also provides organometallic complexes which exhibit RASI photoemission, and the use of the same in light-emitting devices such as OLEDs.Type: GrantFiled: September 9, 2016Date of Patent: June 30, 2020Assignees: UEA ENTERPRISES LIMITED, CAMBRIDGE ENTERPRISE LIMITEDInventors: Manfred Bochmann, Alexander Sergeyevich Romanov, Daniel John Nicholas Credgington, Dawei Di, Le Yang
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Publication number: 20200121807Abstract: Provided is a pharmaceutical composition comprising a taxane and a sphingosine kinase 1 (SK1) inhibitor, a kit comprising a first pharmaceutical composition comprising a taxane and a second pharmaceutical composition comprising an SK1 inhibitor, and a taxane for use in a method of treating cancer, wherein the taxane is administered simultaneously, separately or sequentially with an SK1 inhibitor.Type: ApplicationFiled: December 19, 2017Publication date: April 23, 2020Applicant: UEA Enterprises LimitedInventors: Heba ALSHAKER, Qi WANG, Shyam Srivats RASIPUR, Dmitry PSHEZHETSKIY
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Patent number: 10283781Abstract: The present invention relates to the use of an electrocatalytic frustrated Lewis pair system in either an energy generation device such as a fuel cell or an energy storage device such as a battery or capacitor.Type: GrantFiled: February 2, 2015Date of Patent: May 7, 2019Assignee: UEA Enterprises LimitedInventors: Andrew Edward Ashley, Gregory Wildgoose, Elliot Lawrence
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Publication number: 20190131549Abstract: The present invention provides complexes of the formula (L)M(X), in which M is a metal atom selected from copper, silver and gold; L is a carbene ligand; and X is a monoanionic ligand. The complexes are useful as light emitters in the emissive zone of light-emitting devices such as OLEDs. The present invention also provides organometallic complexes which exhibit RASI photoemission, and the use of the same in light-emitting devices such as OLEDs.Type: ApplicationFiled: September 9, 2016Publication date: May 2, 2019Applicants: UEA ENTERPRISES LIMITED, CAMBRIDGE ENTERPRISE LIMITEDInventors: Manfred BOCHMANN, Alexander Sergeyevich ROMANOV, Daniel John Nicholas CREDGINGTON, Dawei DI, Le YANG
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Publication number: 20170179499Abstract: The present invention relates to the use of an electrocatalytic frustrated Lewis pair system in either an energy generation device such as a fuel cell or an energy storage device such as a battery or capacitor.Type: ApplicationFiled: February 2, 2015Publication date: June 22, 2017Applicant: UEA Enterprises LimitedInventors: Andrew Edward Ashley, Gregory Wildgoose, Elliot Lawrence
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Patent number: 7480419Abstract: An image signal is processed by deriving measurements representing the luminance of a signal; calculating values relating to the local mean, the local standard deviation, the local maximum and/or the local minimum; and computing therefrom local standard coordinates such as z-scores which are independent of brightness and contrast.Type: GrantFiled: December 1, 2003Date of Patent: January 20, 2009Assignee: UEA Enterprises LimitedInventor: Graham Finlayson