Abstract: The present disclosure relates to systems and methods for pulse parameter modulation. The systems may perform the methods to obtain information related to a treatment plan; determine a backward window based on the information related to the treatment plan, within which one or more radiation pulses have been transmitted; determine backward information associated with the backward window based on the information related to the treatment plan and the backward window; determine a forward window based on the information related to the treatment plan, within which one or more radiation pulses are to be transmitted; determine forward information associated with the forward window based on the information related to the treatment plan, the backward information, and the forward window; and determine one or more pulse parameters of the forward window based on the forward information.

Abstract: The present disclosure provides a system and method for dose measurement in radiation therapy. The method may include obtaining a beam model and a detector model related to a radiation device, and a reference image and a treatment plan related to the subject, and determining a synthetic image based on the beam model, the detector model, and the reference image. The method may also include obtaining a treatment image by performing at least a portion of the treatment plan including delivering at least a radiation beam toward the subject using the radiation device, and determining one or more scaling factors. The method may further include determining a synthetic estimate of the treatment image based on the synthetic image and the one or more scaling factors. The method may further include estimating radiation dose deposition based on the treatment image and the synthetic estimate of the treatment image.

Abstract: The present disclosure provides a system and method for dose measurement in radiation therapy. The method may include obtaining a beam model and a detector model related to a radiation device, and a reference image and a treatment plan related to the subject, and determining a synthetic image based on the beam model, the detector model, and the reference image. The method may also include obtaining a treatment image by performing at least a portion of the treatment plan including delivering at least a radiation beam toward the subject using the radiation device, and determining one or more scaling factors. The method may further include determining a synthetic estimate of the treatment image based on the synthetic image and the one or more scaling factors. The method may further include estimating radiation dose deposition based on the treatment image and the synthetic estimate of the treatment image.

Abstract: A system and method for generating augmented segmented image set obtain are provided. The method may include: obtaining a first image including a first anatomical structure of a first object; determining first feature data of the first anatomical structure; determining one or more first transformations related to the first anatomical structure, wherein a first transformation includes a transformation type and one or more transformation parameters related to the transformation type; applying the one or more first transformations to the first feature data of the first anatomical structure to generate second feature data of the first anatomical structure; and generating a second image based on the second feature data of the first anatomical structure.

Abstract: The present disclosure relates to systems and methods for pulse parameter modulation. The systems may perform the methods to obtain information related to a treatment plan; determine a backward window based on the information related to the treatment plan, within which one or more radiation pulses have been transmitted; determine backward information associated with the backward window based on the information related to the treatment plan and the backward window; determine a forward window based on the information related to the treatment plan, within which one or more radiation pulses are to be transmitted; determine forward information associated with the forward window based on the information related to the treatment plan, the backward information, and the forward window; and determine one or more pulse parameters of the forward window based on the forward information.

Abstract: A target assembly for generating radiation may comprise a target, a substrate and a window. The target may be capable of generating first radiation when impinged by a beam. The window may be at least partially permeable to the beam. The window and the substrate may form at least part of a hermetically sealed chamber and the target may be positioned in the chamber. The chamber may be filled with air having a normal or reduced content of oxygen.

Abstract: A system and method for generating augmented segmented image set obtain are provided. The method may include: obtaining a first image including a first anatomical structure of a first object; determining first feature data of the first anatomical structure; determining one or more first transformations related to the first anatomical structure, wherein a first transformation includes a transformation type and one or more transformation parameters related to the transformation type; applying the one or more first transformations to the first feature data of the first anatomical structure to generate second feature data of the first anatomical structure; and generating a second image based on the second feature data of the first anatomical structure.

Abstract: A multi-leaf collimator is provided. The multi-leaf collimator may include a plurality of leaves configured to shield radiation beams. At least two leaves of the plurality of leaves may be movable in a direction parallel to each another. Each leaf of at least some of the plurality of leaves may be configured to be movable between at least two positions. At least one of the at least two positions may be adjustable.

Abstract: The present disclosure relates to systems and methods for pulse parameter modulation. The systems may perform the methods to obtain information related to a treatment plan; determine a backward window based on the information related to the treatment plan, within which one or more radiation pulses have been transmitted; determine backward information associated with the backward window based on the information related to the treatment plan and the backward window; determine a forward window based on the information related to the treatment plan, within which one or more radiation pulses are to be transmitted; determine forward information associated with the forward window based on the information related to the treatment plan, the backward information, and the forward window; and determine one or more pulse parameters of the forward window based on the forward information.

Abstract: A system and method for generating augmented segmented image set obtain are provided. The method may include: obtaining a first image including a first anatomical structure of a first object; determining first feature data of the first anatomical structure; determining one or more first transformations related to the first anatomical structure, wherein a first transformation includes a transformation type and one or more transformation parameters related to the transformation type; applying the one or more first transformations to the first feature data of the first anatomical structure to generate second feature data of the first anatomical structure; and generating a second image based on the second feature data of the first anatomical structure.

Abstract: A radiation treatment device may include a first dosimeter and a second dosimeter. Quantum efficiency of the first dosimeter may be lower than quantum efficiency of the second dosimeter. A method for monitoring beam energy may include receiving a first signal generated by a first dosimeter, receiving a second signal generated by a second dosimeter, receiving a third signal generated by the first dosimeter and receiving a fourth signal generated by the second dosimeter. The first signal and the second signal may be associated with a first radiation beam. The second signal and the fourth signal may be associated with a second radiation beam. The method may also include determining whether there is a difference between the beam energy of the first radiation beam and the second radiation beam based on at least one of the first signal, the second signal, the third signal or the fourth signal.

Abstract: A target assembly for generating radiation may comprise a target, a substrate and a window. The target may be capable of generating first radiation when impinged by a beam. The window may be at least partially permeable to the beam. The window and the substrate may form at least part of a hermetically sealed chamber and the target may be positioned in the chamber. The chamber may be filled with air having a normal or reduced content of oxygen.

Abstract: A system and method for adapting treatment plan are provided. The method may include: obtaining a planning image of a region of interest relating to a first treatment fraction of a first treatment plan; obtaining a first image of the region of interest relating to a first scan of the region of interest with a first dose level; comparing the planning image with the first image to generate a first comparison result; determining whether the first comparison result satisfies a first replanning condition; causing, in response to a determination that the first comparison result satisfies the first replanning condition, one or more scanners to perform a second scan with a second dose level to provide a second image; and generating a second treatment plan according to the second image, wherein the second dose level is higher than the first dose level.

Abstract: The present disclosure relates to systems and methods for pulse parameter modulation. The systems may perform the methods to obtain information related to a treatment plan; determine a backward window based on the information related to the treatment plan, within which one or more radiation pulses have been transmitted; determine backward information associated with the backward window based on the information related to the treatment plan and the backward window; determine a forward window based on the information related to the treatment plan, within which one or more radiation pulses are to be transmitted; determine forward information associated with the forward window based on the information related to the treatment plan, the backward information, and the forward window; and determine one or more pulse parameters of the forward window based on the forward information.