Abstract: The present disclosure relates to a method for preparing a filler composition for molding. The method for preparing a filler composition for molding includes the operations of: a) providing PLGA microparticles consisting of poly (lactic-co-glycolic acid) (PLGA), a biodegradable polymer; b) providing PDO microparticles consisting of polydioxanone (PDO); c) preparing a mixture by mixing the PLGA microparticles and the PDO microparticles; d) injecting plasma into the mixture to perform a plasma surface treatment on the PLGA microparticles and the PDO microparticles; e) dispersing the plasma-treated mixture into a solution containing a dispersant composition to prepare a dispersant solution; and f) freeze-drying the dispersant solution to form the composite containing the PLGA microparticles and the PDO microparticles.
Type:
Application
Filed:
February 5, 2024
Publication date:
August 8, 2024
Applicant:
ULTRA V CO., LTD.
Inventors:
Han Jin KWON, Jung Ryul HAM, Won Ku LEE, Yeon Ju GU
Abstract: Disclosed herein are a biodegradable polymer microparticle for a filler, a freeze-dried body including the same, a manufacturing method thereof, and filler injection including the freeze-dried body. The freeze-dried body includes hydrophilic surface-treated biodegradable polymer microparticle and a biocompatible carrier, wherein the hydrophilic surface-treated biodegradable polymer microparticle has an average particle diameter (D50) of 20 to 50 ?m and is polydioxanone which has a carboxyl group on the surface thereof. The hydrophilic surface-treated biodegradable polymer microparticle is a plasma surface-treated product or a base surface-treated product using discharge of the biodegradable polymer microparticle. The content of the biocompatible carrier is 1 to 5 parts by weight based on 100 parts by weight of the freeze-dried body.
Type:
Application
Filed:
January 16, 2024
Publication date:
May 16, 2024
Applicant:
ULTRA V CO., LTD.
Inventors:
Cheong Cheon LEE, Lia PRISCILLA, Min Seok KWAK, Jung Woo HAN, Jung Ryul HAM, Han Jin KWON
Abstract: Disclosed herein are a biodegradable polymer microparticle for a filler comprising a core and a shell, wherein the core contains secondary particles including aggregates of a plurality of primary particles, the shell has a raspberry shaped structure, an average particle diameter (D50) of the biodegradable polymer microparticle ranges from 20 to 200 ?m, a manufacturing method thereof, a freeze-dried body including the same, and filler injection including the same.
Type:
Grant
Filed:
January 21, 2022
Date of Patent:
March 7, 2023
Assignee:
ULTRA V CO., LTD.
Inventors:
Cheong Cheon Lee, Lia Priscilla, Min Seok Kwak, Jung Woo Han, Jung Ryul Ham, Han Jin Kwon
Abstract: Disclosed herein are a biodegradable polymer microparticle for a filler comprising a core and a shell, wherein the core contains secondary particles including aggregates of a plurality of primary particles, the shell has a raspberry shaped structure, an average particle diameter (D50) of the biodegradable polymer microparticle ranges from 20 to 200 ?m, a manufacturing method thereof, a freeze-dried body including the same, and filler injection including the same.
Type:
Application
Filed:
January 21, 2022
Publication date:
July 28, 2022
Applicant:
ULTRA V CO., LTD.
Inventors:
Cheong Cheon LEE, Lia PRISCILLA, Min Seok KWAK, Jung Woo HAN, Jung Ryul HAM, Han Jin KWON
Abstract: Disclosed herein are a biodegradable polymer microparticle for a filler, a freeze-dried body including the same, a manufacturing method thereof, and filler injection including the freeze-dried body. The freeze-dried body includes hydrophilic surface-treated biodegradable polymer microparticle and a biocompatible carrier, wherein the hydrophilic surface-treated biodegradable polymer microparticle has an average particle diameter (D50) of 20 to 50 ?m and is polydioxanone which has a carboxyl group on the surface thereof. The hydrophilic surface-treated biodegradable polymer microparticle is a plasma surface-treated product or a base surface-treated product using discharge of the biodegradable polymer microparticle. The content of the biocompatible carrier is 1 to 5 parts by weight based on 100 parts by weight of the freeze-dried body.
Type:
Application
Filed:
January 24, 2022
Publication date:
July 28, 2022
Applicant:
ULTRA V CO., LTD.
Inventors:
Cheong Cheon LEE, Lia PRISCILLA, Min Seok KWAK, Jung Woo HAN, Jung Ryul HAM, Han Jin KWON
Abstract: The present invention relates to a method for manufacturing polydioxanone particles (PDO) for a filler, more particularly to a method for manufacturing polydioxanone particles, which includes a step of mixing a solution of polydioxanone dissolved in a perfluoroalcohol with a polymer emulsion containing a polyethylene oxide-polypropylene oxide-polyethylene oxide terpolymer at a predetermined ratio to generate polydioxanone particles and then recovering the polydioxanone particles through aging and washing. The polydioxanone particles manufactured by the manufacturing method of the present invention can be favorably used as an injection for regenerating skin tissues.
Type:
Grant
Filed:
July 16, 2015
Date of Patent:
May 29, 2018
Assignee:
ULTRA V CO., LTD.
Inventors:
Myung Choi, Sang Jin Kim, Byeung Mo Chang, Michael Gilbert Douglas, Han Jin Kwon
Abstract: The present invention relates to a method for manufacturing polydioxanone particles (PDO) for a filler, more particularly to a method for manufacturing polydioxanone particles, which includes a step of mixing a solution of polydioxanone dissolved in a perfluoroalcohol with a polymer emulsion containing a polyethylene oxide-polypropylene oxide-polyethylene oxide terpolymer at a predetermined ratio to generate polydioxanone particles and then recovering the polydioxanone particles through aging and washing. The polydioxanone particles manufactured by the manufacturing method of the present invention can be favorably used as an injection for regenerating skin tissues.
Type:
Application
Filed:
July 16, 2015
Publication date:
May 11, 2017
Applicant:
ULTRA V CO., LTD.
Inventors:
Myung CHOI, Sang Jin KIM, Byeung Mo CHANG, Michael Gilbert DOUGLAS, Han Jin KWON