Abstract: In an arrangement for producing a directional and cooled gas jet in an ion source with a gas inlet or a UV/fluorescence detection cell including a gas inlet, wherein a capillary extends with one end into the interior of the ion source which is evacuated, the one end is provided with a nozzle for discharging a gas sample into the ion source while being subjected to adiabatic cooling and the width of the nozzle opening is at most 40% of the inner diameter of the capillary and the capillary is heatable for preventing condensation of gas sample components in the nozzle.

Abstract: In a process for influencing the properties of incineration residues from an incineration plant, in particular a waste incineration plant, the incineration is controlled sot that a sintering and/or fusing of the slag takes place as earl as in the incineration bed of the main incineration zone, and as yet unsintered or unfused incineration residues are separated off at the end of the incineration operation and fed back to the incineration operation.

Abstract: The present invention provides a method of determining hybridization on a microarry, preferably a DNA-chip.

Abstract: The present invention relates to new DNA sequences, a method for producing new plants which contain a new DNA sequence, the coding sequence thereof being expressed after ozone induction. The invention also relates to said new plants and the use of DNA sequences to produce ozone-responsive gene expression in plants and plant cells. Moreover, it relates to a new promoter, the specificity thereof being increased by removal of the ozone response capacity thereof.

Abstract: The invention refers to a novel recombinant vectors useful for gene therapy of viral infections and of diseases associated with B and T cells. The present invention relates, furthermore, to novel usages of the two products of the open reading frame of mouse mammary tumour virus.

Abstract: In a method and apparatus for detecting compounds in a gas stream, the gas stream with the compounds to be detected is conducted into an ionization chamber of a mass spectrometer where the gas stream is subjected in the ion chamber in a pulsed manner alternately to UV laser pulses and to vacuum ultraviolet VUV laser pulses and the ions generated thereby are directed into the mass spectrometer for detection therein to determine the compounds in the gas stream.

Abstract: The present invention describes monoclonal antibodies which are useful for the specific detection and therapy of diffuse gastric carcinoma. Further embodiments describe therapeutic and diagnostic means for the detection and for the therapy of diffuse gastric carcinomas as well as methods for the detection and therapy of diffuse gastric carcinomas.

Abstract: According to the invention, there is provided a vector for the expression of immunoglobulin-cytokin fusion proteins in malignant B cells at least containing operably linked to each other

Abstract: A device for flow rate limitation at low differential pressures, particularly for limiting the volumetric inhalation flow during inhalation of therapeutic aerosols, consists of a housing 11 including an aspiration orifice 14, an inhalation orifice 15 and a flow passage 23 disposed therebetween. The flow passage has a flat elongate cross-section with flexible large-area walls 18, 20 having a cross-sectional area adapted to be reduced, as a function of the differential pressure prevailing between the inhalation orifice and the aspiration orifice, as well as of the flexibility of the material of the walls, to a size appropriate for a predetermined volumetric maximum inhalation flow.

Abstract: According to the invention, there is provided a vector for the expression of immunoglobulin-cytokine fusion proteins in malignant B cells at least containing operably linked to each other (a) a region of at least 1.5 kb which is homologous to a region of the &mgr; intron or the &kgr; intron and which lacks a functional C&mgr; or C&kgr; enhancer or contains a non-functional C82 or C&kgr; enhancer; (b) at least one DNA sequence encoding a domain of an immunoglobulin or a part thereof; (c) a DNA sequence encoding a cytokine; and (d) a marker gene selectable in eukaryotic B cells and lacking a functional enhancer region wherein the expression of said marker following integration is controlled by the cellular C&mgr; or C&kgr; enhancer.

Abstract: Transcription factor responsive elements, target genes, and co-factors of a transcription factor, either individually or in combination, are identified by integrating into the genome of a eukaryotic cell a gene trap vector that includes a reporter gene, a polyadenylation site, and a selectable marker gene, selecting the cells in which the gene trap vector is successfully integrated and contacting those cells with the transcription factor, then identifying and cultivating those cells having a gene into which the gene trap vector has been integrated and in which the reporter gene activity has been altered by interaction between the transcription factor and a transcription factor responsive element of that gene, and identifying the transcription factor responsive element, target gene, or cofactor that interacts with the transcription factor.

Abstract: The process for minimizing the concentration of toxic organic compounds in the fly dusts of incineration plants comprises, when special combustion conditions are detected which lead to the formation of organic pollutants, in particular dioxins/furans and/or precursor compounds of dioxins/furans, recirculating the fly dusts produced in the incineration plant to the combustion process for destruction of these compounds.

Abstract: To improve slag quality, on a fired grate, at the end of the main combustion process, where burnable fractions are still present in addition to slag components which are already forming, the burnup rate or burnup intensity is changed by varying the primary air rate in sequential time sections, the time sections preferably being in a ratio of 1:1 and the reduced primary air rate being 50 to 70% of the standard primary air rate.

Abstract: In a gas inlet structure for an ion source, including a capillary for the admission of a sample gas, which capillary is disposed in a guide tube for discharging a sample gas into the guide tube, the guide tube has an open end disposed in the ion source. The guide tube includes a valve for the pulsed admission of a carrier gas to the guide tube. The guide tube, the valve and the capillary are supported in a sealed support housing from which the guide tube with the capillary disposed therein projects into the ion source for supplying thereto the sample gas in a pulsed manner.

Abstract: In the process for treating incineration residues, the incineration is controlled in such a way that a sintering and/or fusing of the slag takes place as early as in the incineration bed of the main incineration zone. The incineration residues produced are quenched in a wet slag remover and conveyed out of the latter. The wet incineration residues which come out of the wet slag remover are firstly divided into two fractions by means of a screening operation, after which the main fraction is washed with water taken from the wet slag remover, and in the process adhering fine pieces are separated off. The washed pieces of the incineration residues are fed for reuse. The washing water together with the ultra fine pieces which have been taken up during the washing operation pass into the wet slag remover. The fine fraction produced during the mechanical separation operation is fed back to the incineration operation.

Abstract: In the process for treating incineration residues from waste incineration plants, the incineration material is incinerated on a furnace grate. The incineration residues produced are quenched in a wet slag remover and conveyed out of the latter. The wet incineration residues which come out of the wet slag remover are firstly divided into two fractions by means of a screening operation, after which the main fraction is washed with water taken from the wet slag remover, and in the process adhering fine pieces are separated off. The washed pieces of the incineration residues are fed for reuse. The washing water together with the ultra fine pieces which have been taken up during the washing operation pass into the wet slag remover. The fine fraction produced during the mechanical separation operation is fed back to the incineration operation.

Abstract: The process for influencing the properties of incineration residues from an incineration plant, in particular a waste incineration plant, essentially consists in controlling the incineration in such a way that a sintering and/or fusing of the slag takes place as early as in the incineration bed of the main incineration zone, and that as yet unsintered or unfused incineration residues are separated off at the end of the incineration operation and fed back to the incineration operation.

Abstract: A device for administration of a medicated aerosol via the lungs consists of an inhalation mouthpiece 11, with an associated adjustable vaporizer 12, and of a compressed-air control valve 14 through which a pre-settable (13) volumetric flow of compressed air can be discharged to the vaporizer 12 containing the liquid medicament throughout a settable period of time. For operation of the device an electronic controller is provided on which the vaporizing period of the vaporizer and a pause interval can be set, with provisions being made for triggering the beginning of the vaporizing operation by means of a pressure sensor responsive to a suction pressure in the mouthpiece.

Abstract: The present invention describes a means for the treatment of multiple myeloma. Deletion mutants of the gp130 protein of the IL-3 receptor are presented which inhibit the binding of Hck tyrosine kinase and the growth of tumor cells, particularly of myeloma cells.

Abstract: Multiple myeloma is treated by deletion mutants of the gp130 protein of the IL-3 receptor. These mutants inhibit the binding of Hck tyrosine kinase and the growth of tumor cells, particularly myeloma cells.